Karolis Skučas, Aušra Balčiūnaitė, Nomeda Basevičienė
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引用次数: 0
Abstract
Aim: To analyze the latest systemic and topical recurrent aphthous stomatitis (RAS) treatment methods that could help patients in their daily lives.
Material and methods: A systematic literature review was performed of randomized control trials in English identified in MEDLINE (PubMed), Cochrane Central Register of Controlled Trials (Cochrane Library), Researchgate, published between 2018 and 2023. Studies had to be performed in vivo.
Results: 34 randomized clinical trials matched all criterias and were included in systematic literature review. A wide variety of topical and systemic agents are suggested for the treatment of RAS.
Conclusion: Topical medications can promote the healing time of ulcers and relieve the pain, but most of the time can not decrease the frequency of RAS relapse. However, for continuous RAS, treatment with systemic medication should be considered.
目的:分析最新的全身和局部复发性口腔炎(RAS)治疗方法，为患者的日常生活提供帮助。材料和方法:对2018年至2023年间发表在MEDLINE (PubMed)、Cochrane Central Register of Controlled trials (Cochrane Library)、Researchgate中发现的英文随机对照试验进行系统文献综述。研究必须在体内进行。结果:34项随机临床试验符合所有标准，纳入系统文献综述。各种各样的局部和全身药物被建议用于治疗RAS。结论:局部用药可促进溃疡愈合时间，减轻疼痛，但多数情况下不能降低RAS复发频率。然而，对于持续的RAS，应考虑全身性药物治疗。
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