The effect of environmental change, planned and unplanned life events on the long-term outcome of common mental disorders.

IF 3.6 2区 医学 Q1 PSYCHIATRY Social Psychiatry and Psychiatric Epidemiology Pub Date : 2024-09-01 Epub Date: 2023-07-10 DOI:10.1007/s00127-023-02520-1
Peter Tyrer, Conor Duggan, Min Yang, Helen Tyrer
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Abstract

Purpose: To examine the nature of positive and negative environmental change on clinical outcome in 210 patients presenting with anxiety and depression and followed up over 30 years.

Methods: In addition to clinical assessments, major environmental changes, particularly after 12 and 30 years, were recorded in all patients by a combination of self-report and taped interviews. Environmental changes were separated into two major groups, positive or negative, determined by patient opinion.

Results: In all analyses positive changes were found to be associated with better outcome at 12 years with respect to accommodation (P = 0.009), relationships (P = 007), and substance misuse (P = 0.003), with fewer psychiatric admissions (P = 0.011) and fewer social work contacts at 30 years (P = 0.043). Using a consolidated outcome measure positive changes were more likely than negative ones to be associated with a good outcome at 12 and 30 years (39% v 3.6% and 30.2% v 9.1%, respectively). Those with personality disorder at baseline had fewer positive changes (P = 0.018) than others at 12 years and fewer positive occupational changes at 30 years (P = 0.041). Service use was greatly reduced in those with positive events with 50-80% more time free of all psychotropic drug treatment (P < 0.001). Instrumental positive change had greater effects than imposed changes.

Conclusions: Positive environmental change has a favourable impact on clinical outcome in common mental disorders. Although studied naturalistically in this study the findings suggest that if harnessed as a therapeutic intervention, as in nidotherapy and social prescribing, it would yield therapeutic dividends.

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环境变化、有计划和无计划的生活事件对常见精神障碍长期结果的影响。
目的:对 210 名焦虑症和抑郁症患者进行为期 30 年的随访,研究环境的积极和消极变化对临床结果的影响:除临床评估外,还通过自我报告和录音访谈记录所有患者的主要环境变化,尤其是 12 年和 30 年后的变化。根据患者的意见,将环境变化分为积极和消极两大类:在所有分析中发现,积极变化与 12 年后在住宿(P = 0.009)、人际关系(P = 007)和药物滥用(P = 0.003)方面的较好结果有关,与 30 年后较少的精神病入院(P = 0.011)和较少的社会工作接触(P = 0.043)有关。采用综合结果测量法,12 年和 30 年后,积极变化比消极变化更有可能与良好结果相关联(分别为 39% 对 3.6% 和 30.2% 对 9.1%)。基线时患有人格障碍的人在 12 年后的积极变化(P = 0.018)少于其他人,在 30 年后的积极职业变化(P = 0.041)也少于其他人。有积极事件发生的人使用服务的情况大大减少,免于所有精神药物治疗的时间增加了 50%-80%(P 结论:积极的环境变化对人格障碍患者有积极的影响:积极的环境变化对常见精神障碍的临床结果具有有利影响。尽管本研究采用的是自然研究方法,但研究结果表明,如果将其作为一种治疗干预措施加以利用,就像尼德疗法和社会处方一样,它将产生治疗红利。
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来源期刊
CiteScore
8.50
自引率
2.30%
发文量
184
审稿时长
3-6 weeks
期刊介绍: Social Psychiatry and Psychiatric Epidemiology is intended to provide a medium for the prompt publication of scientific contributions concerned with all aspects of the epidemiology of psychiatric disorders - social, biological and genetic. In addition, the journal has a particular focus on the effects of social conditions upon behaviour and the relationship between psychiatric disorders and the social environment. Contributions may be of a clinical nature provided they relate to social issues, or they may deal with specialised investigations in the fields of social psychology, sociology, anthropology, epidemiology, health service research, health economies or public mental health. We will publish papers on cross-cultural and trans-cultural themes. We do not publish case studies or small case series. While we will publish studies of reliability and validity of new instruments of interest to our readership, we will not publish articles reporting on the performance of established instruments in translation. Both original work and review articles may be submitted.
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