Successful Management of Extensively Drug Resistant Pseudomonas aeruginosa-Infectious Scleritis after Pterygium Surgery.

IF 2.6 4区 医学 Q2 OPHTHALMOLOGY Ocular Immunology and Inflammation Pub Date : 2024-09-01 Epub Date: 2023-07-11 DOI:10.1080/09273948.2023.2232037
Samruddhi Dalal, Somasheila I Murthy, Ketan Deogaokar, Joveeta Joseph, Sanhita Roy
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Abstract

Introduction and purpose: We report a case of extensively drug-resistant (XDR) Pseudomonas aeruginosa (PA) scleritis after pterygium surgery.

Methods: Case report.

Results: A 58-year-old farmer presented with a 40-day history of severe pain, swelling, and blurred vision after a pterygium excision was performed at another institute. The patient was on multiple medications with no relief. The examination showed a nasally located scleral thinning in his right eye, with ulceration and infiltrates. Microbiology revealed Pseudomonas aeruginosa, which showed intermediate sensitivity to colistin only. The patient was administered topical (0.19%) and intravenous colistin and dexamethasone. There was a rapid reduction in symptoms, and the lesions healed over the next 2 months.

Conclusions: To the best of our knowledge, this is the first case report of XDR-PA scleritis. We suggest the possibility of evolving drug resistance caused by the iatrogenic use of antibiotics during the early stages of the disease course.

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成功治疗翼状胬肉手术后的广泛耐药铜绿假单胞菌感染性巩膜炎
简介和目的:我们报告了一例翼状胬肉手术后的广泛耐药(XDR)铜绿假单胞菌(PA)巩膜炎病例:方法:病例报告:一名 58 岁的农民在另一家医院接受翼状胬肉切除术后,因剧烈疼痛、肿胀和视力模糊就诊 40 天。患者服用了多种药物,但症状没有缓解。检查显示,他的右眼鼻侧巩膜变薄,伴有溃疡和浸润。微生物学检查显示为铜绿假单胞菌,仅对可乐定呈中度敏感性。患者接受了局部(0.19%)和静脉注射可乐定和地塞米松的治疗。症状迅速减轻,皮损在随后的两个月内愈合:据我们所知,这是首例 XDR-PA 性巩膜炎病例报告。结论:据我们所知,这是首例 XDR-PA 性巩膜炎病例,我们认为可能是在病程早期阶段先天性使用抗生素导致耐药性不断发展。
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来源期刊
CiteScore
6.20
自引率
15.20%
发文量
285
审稿时长
6-12 weeks
期刊介绍: Ocular Immunology & Inflammation ranks 18 out of 59 in the Ophthalmology Category.Ocular Immunology and Inflammation is a peer-reviewed, scientific publication that welcomes the submission of original, previously unpublished manuscripts directed to ophthalmologists and vision scientists. Published bimonthly, the journal provides an international medium for basic and clinical research reports on the ocular inflammatory response and its control by the immune system. The journal publishes original research papers, case reports, reviews, letters to the editor, meeting abstracts, and invited editorials.
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