TyG index as a predictor of spontaneous coronary artery dissection in young women.

IF 2.6 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Postgraduate Medicine Pub Date : 2023-09-01 Epub Date: 2023-08-01 DOI:10.1080/00325481.2023.2242760
Uğur Özkan, Muhammet Gürdoğan
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Abstract

Objective: Spontaneous coronary artery dissection (SCAD) is a rare but potentially life-threatening pathology and cases are especially seen in women under 50 years of age and with relatively fewer cardiovascular risk factors. Although risk factors facilitating the development of SCAD have been defined in the literature, modifiable risk factors remain unclear. In this study, it was aimed to investigate the relationship between the triglyceride glucose index (TyG) and the development of SCAD in the population of young women.

Methods: The results of 281 patients were analyzed and compared with each other in terms of clinical, demographic, laboratory parameters, and coronary angiography results.

Results: The mean age was 45 years and all of them were female. When the groups were compared, the TyG and inflammatory parameters were higher in the SCAD group (p < 0.001). When these two groups with low cardiovascular risk factors were compared in logistic regression analysis, high TyG was found to be an independent predictor of SCAD development in young women (p < 0.001).

Conclusion: As a result, our study shows that the development of these non-atherosclerotic conditions can be predicted by simple biochemical tests in young women with low atherosclerotic cardiovascular risk factors.

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TyG指数作为年轻女性自发性冠状动脉夹层的预测指标。
目的:自发性冠状动脉夹层(SCAD)是一种罕见但可能危及生命的病理学,尤其见于50岁以下的女性 年龄和心血管风险因素相对较少。尽管文献中已经定义了促进SCAD发展的风险因素,但可改变的风险因素仍不清楚。在本研究中,旨在调查年轻女性人群中甘油三酯-葡萄糖指数(TyG)与SCAD发展之间的关系。方法:对281例患者的临床、人口学、实验室参数和冠状动脉造影结果进行分析和比较。结果:平均年龄为45岁 她们都是女性。当比较两组时,SCAD组的TyG和炎症参数较高(p p 结论:因此,我们的研究表明,在动脉粥样硬化心血管危险因素较低的年轻女性中,通过简单的生化测试可以预测这些非动脉粥样硬化疾病的发展。
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来源期刊
Postgraduate Medicine
Postgraduate Medicine 医学-医学:内科
CiteScore
6.10
自引率
2.40%
发文量
110
审稿时长
6-12 weeks
期刊介绍: Postgraduate Medicine is a rapid peer-reviewed medical journal published for physicians. Tracing its roots back to 1916,  Postgraduate Medicine  was established by Charles Mayo, MD, as a peer-to-peer method of communicating the latest research to aid physicians when making treatment decisions, and it maintains that aim to this day. In addition to its core subscriber base, Postgraduate Medicine is distributed to hundreds of US-based physicians within internal medicine and family practice.
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