Evolution of COVID-19 infection characteristics in a Lebanese cohort of inpatients during different pandemic periods.

IF 4.9 4区 医学 Q1 PARASITOLOGY Pathogens and Global Health Pub Date : 2024-03-01 Epub Date: 2023-07-23 DOI:10.1080/20477724.2023.2239492
Tony Haykal, Jonathan Mina, Mohamad Fleifel, Hani Dimassi, Janane Nasr, Ahmad Mahdi, Ranime Harb, Ghida El Hout, Elissar Franjieh, Jacques Mokhbat, Anna Farra, Mariana Helou, Rola Husni
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Abstract

This study aims to describe COVID-19 patients characteristics, laboratory and imaging results, and the different outcomes of patients admitted to the Lebanese American University Medical Center-Rizk Hospital over a period of 9 months. In this observational retrospective study, data were obtained from electronic medical records of 491 male and female patients from the ages of 17 to 97. Analysis of the patients was performed in 3 periods: August 2020 to October 20 November 202020 to January 2021 and February 2021 to April 2021 corresponding with 3 waves of newly diagnosed cases during this period. The sample showed a male predominance with an average age of 63. The average hospitalization length was 10.1 days. The majority of patients were discharged to quarantine. The distribution of hospitalized cases was significantly correlated to the monthly distribution of newly COVID-19 cases in Lebanon. There was no significant difference in patient's characteristics between the 3 periods of the study (gender, age, body mass index, smoking, and medical conditions). Clinical presentations of the patients varied between the 3 periods. Similarly, the course and outcome of infection varied. Patients received less oxygen during period 1, while more patients were cured during period 3. This study presents the first Lebanese cohort of COVID-19 patients with their medical background, clinical presentation, laboratory results, radiological findings and course of infection with its outcome. It also shows how the relations between the medical manifestation of the COVID-19 pandemic and the socio-political measures of infection control are deeply intertwined.

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不同大流行时期黎巴嫩住院病人队列中 COVID-19 感染特征的演变。
本研究旨在描述 COVID-19 患者的特征、实验室和成像结果,以及黎巴嫩美国大学医学中心-里兹克医院在 9 个月内收治的患者的不同结果。在这项观察性回顾研究中,我们从 491 名年龄在 17 岁至 97 岁之间的男女患者的电子病历中获取了数据。对患者的分析分三个阶段进行:2020 年 8 月至 2020 年 10 月 2020 年 11 月至 2021 年 1 月以及 2021 年 2 月至 2021 年 4 月,与这一时期的 3 波新诊断病例相对应。样本显示男性居多,平均年龄为 63 岁。平均住院时间为 10.1 天。大多数患者出院后都接受了隔离治疗。住院病例的分布与黎巴嫩 COVID-19 新发病例的每月分布有明显的相关性。研究的三个阶段在患者特征(性别、年龄、体重指数、吸烟和医疗条件)方面没有明显差异。三个时期的患者临床表现各不相同。同样,感染的过程和结果也各不相同。第 1 期的患者吸氧较少,而第 3 期治愈的患者较多。本研究介绍了黎巴嫩第一批 COVID-19 患者的医学背景、临床表现、实验室结果、放射学检查结果以及感染过程和结果。研究还显示了 COVID-19 大流行病的医学表现与感染控制的社会政治措施之间的关系。
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来源期刊
Pathogens and Global Health
Pathogens and Global Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-PARASITOLOGY
CiteScore
6.00
自引率
0.00%
发文量
60
审稿时长
6-12 weeks
期刊介绍: Pathogens and Global Health is a journal of infectious disease and public health that focuses on the translation of molecular, immunological, genomics and epidemiological knowledge into control measures for global health threat. The journal publishes original innovative research papers, reviews articles and interviews policy makers and opinion leaders on health subjects of international relevance. It provides a forum for scientific, ethical and political discussion of new innovative solutions for controlling and eradicating infectious diseases, with particular emphasis on those diseases affecting the poorest regions of the world.
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