New bone formation accelerates during lower limb lengthening and deformity correction in children with Ollier's disease.

IF 3 2区 医学 Q1 ORTHOPEDICS Journal of Orthopaedics and Traumatology Pub Date : 2023-07-31 DOI:10.1186/s10195-023-00717-3
Chunxing Wu, Yiyong Huang, Peng Huang, Yueqiang Mo, Dahui Wang, Bo Ning
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Abstract

Background: Ollier's disease can cause severe length discrepancy of the lower extremities and deformity in children. Osteotomy and limb lengthening with external fixation can correct the limb deformity. This study evaluated (1) whether the duration of external fixation was reduced in patients with Ollier's disease, and (2) the incidence of complications such as pin tract infection, external fixation loosening, and joint stiffness.

Methods: Two groups were compared with respect to age, angular correction (AC), lengthening gap (LG), distraction index (DI), lengthening length (LL), lengthening length percentage (L%), lengthening index (LI), bone healing index (BHI), and external fixation index (EFI). Group 1 (Ollier's disease) comprised nine patients undergoing 11 lower limb lengthening procedures using external fixators; group 2 (control, normal lengthened bone) comprised 28 patients undergoing 29 lengthening procedures with external fixators.

Results: In patients with Ollier's disease, full correction of the deformity and full restoration of length were achieved in all cases. In the femur, the mean AC (15.97° vs. 6.72°) and DI (1.11 mm/day vs. 0.78 mm/day) were significantly larger, while the LI (9.71 days/cm vs. 13.49 days/cm), BHI (27.00 days/cm vs. 42.09 days/cm), and EFI (37.86 days/cm vs. 56.97 days/cm) were all significantly shorter in group 1 than in group 2 (p < 0.05). In the tibia, the mean AC and L% were larger, while the LG, LI, BHI, and EFI were all shorter in group 1 than in group 2. There was no significant difference between the two groups in the incidence of complications.

Conclusion: In children with Ollier's disease, new bone formation accelerated and the healing speed of the lengthened segments was faster throughout the whole lengthening period with external fixation, and full correction of the deformity and full restoration of length could be achieved.

Level of evidence iii:

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奥利埃病患儿在下肢延长和畸形矫正过程中,新骨形成速度加快。
背景:奥利尔病可导致儿童下肢严重长度不一致和畸形。通过外固定进行截骨和肢体延长可以矫正肢体畸形。本研究评估了(1)奥利尔病患者的外固定时间是否缩短,以及(2)针道感染、外固定松动和关节僵硬等并发症的发生率:比较两组患者的年龄、角度矫正(AC)、延长间隙(LG)、牵引指数(DI)、延长长度(LL)、延长长度百分比(L%)、延长指数(LI)、骨愈合指数(BHI)和外固定指数(EFI)。第一组(奥利埃病)包括9名使用外固定器进行11次下肢延长手术的患者;第二组(对照组,正常延长骨)包括28名使用外固定器进行29次延长手术的患者:所有奥利埃病患者的畸形都得到了完全矫正,长度也得到了完全恢复。在股骨中,第 1 组的平均 AC(15.97°对 6.72°)和 DI(1.11 毫米/天对 0.78 毫米/天)明显大于第 2 组,而 LI(9.71 天/厘米对 13.49 天/厘米)、BHI(27.00 天/厘米对 42.09 天/厘米)和 EFI(37.86 天/厘米对 56.97 天/厘米)均明显短于第 2 组(P 结论:在奥利尔病患儿中,第 1 组的平均 AC(15.97°对 6.72°)和 DI(1.11 毫米/天对 0.78 毫米/天)明显大于第 2 组:对于奥利尔病患儿,在整个外固定延长期,新骨形成加快,延长节段愈合速度加快,可实现畸形的完全矫正和长度的完全恢复:
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来源期刊
Journal of Orthopaedics and Traumatology
Journal of Orthopaedics and Traumatology Medicine-Orthopedics and Sports Medicine
CiteScore
4.30
自引率
0.00%
发文量
56
审稿时长
13 weeks
期刊介绍: The Journal of Orthopaedics and Traumatology, the official open access peer-reviewed journal of the Italian Society of Orthopaedics and Traumatology, publishes original papers reporting basic or clinical research in the field of orthopaedic and traumatologic surgery, as well as systematic reviews, brief communications, case reports and letters to the Editor. Narrative instructional reviews and commentaries to original articles may be commissioned by Editors from eminent colleagues. The Journal of Orthopaedics and Traumatology aims to be an international forum for the communication and exchange of ideas concerning the various aspects of orthopaedics and musculoskeletal trauma.
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