[Consensus on targeted drug therapy for spondyloarthritis].

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Abstract

Spondyloarthritis (SpA) is a group of chronic inflammatory conditions that predominantly involve the spine and/or peripheral joints. The clinical manifestations of SpA are diverse and disabling, with SpA adversely affecting the quality of life of patients. Many new medications that target cytokines or pathways specific for the pathogenesis of SpA have been developed and these are becoming increasingly important in the treatment of SpA. However, establishing how to identify the target patient population and standardizing the usage of these drugs are critical issues in the clinical application of these "targeted therapies".Under the leadership of National Clinical Research Center for Dermatologic and Immunologic Diseases (Peking Union Medical College Hospital), the"Consensus on targeted drug therapy for spondyloarthritis" has been developed collaborating with the Rheumatology and Immunology Physicians Committee, Chinese Medical Doctors Association, Rheumatology and Immunology Professional Committee, Chinese Association of Rehabilitation Medicine, Chinese Research Hospital Association Rheumatology and Immunology Professional Committee. This consensus was developed with evidence-based methodology and followed the international standard for consensus development.

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[脊椎关节炎靶向药物治疗的共识]。
脊椎关节炎(SpA)是一组主要累及脊柱和/或周围关节的慢性炎症。SpA的临床表现多样且致残,对患者的生活质量有不利影响。许多针对SpA发病机制的细胞因子或特异性途径的新药物已经开发出来,这些药物在SpA的治疗中变得越来越重要。然而,如何确定目标患者群体和规范这些药物的使用是这些“靶向治疗”在临床应用中的关键问题。在国家皮肤免疫疾病临床研究中心(北京协和医院)的领导下,与风湿病与免疫医师专业委员会、中国医师协会、风湿病与免疫专业委员会、中国康复医学协会、中华医学会风湿病与免疫专业委员会、中华医学会风湿病与免疫专业委员会、中华医学会风湿病与免疫专业委员会、中华医学会风湿病与免疫专业委员会、中华医学会风湿病与免疫专业委员会、中华医学会风湿病与免疫专业委员会、中国研究型医院协会风湿病与免疫学专业委员会。这一共识是以循证方法形成的,并遵循了形成共识的国际标准。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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