A diagnostic method for cardiomyopathy based on multimodal data.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2023-08-28 DOI:10.1515/bmt-2023-0099
Linshan Shen, Xuwei Zhang, Shaobin Huang, Bing Wu, Jingjie Li
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Abstract

Objectives: Currently, a multitude of machine learning techniques are available for the diagnosis of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) by utilizing electrocardiography (ECG) data. However, these methods rely on digital versions of ECG data, while in practice, numerous ECG data still exist in paper form. As a result, the accuracy of the existing machine learning diagnostic models is suboptimal in practical scenarios. In order to enhance the accuracy of machine learning models for diagnosing cardiomyopathy, we propose a multimodal machine learning model capable of diagnosing both HCM and DCM.

Methods: Our study employed an artificial neural network (ANN) for feature extraction from both the echocardiogram report form and biochemical examination data. Furthermore, a convolutional neural network (CNN) was utilized for feature extraction from the electrocardiogram (ECG). The resulting extracted features were subsequently integrated and inputted into a multilayer perceptron (MLP) for diagnostic classification.

Results: Our multimodal fusion model achieved a precision of 89.87%, recall of 91.20%, F1 score of 89.13%, and precision of 89.72%.

Conclusions: Compared to existing machine learning models, our proposed multimodal fusion model has achieved superior results in various performance metrics. We believe that our method is effective.

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基于多模态数据的心肌病诊断方法。
目的:目前,许多机器学习技术可用于利用心电图(ECG)数据诊断肥厚型心肌病(HCM)和扩张型心肌病(DCM)。然而,这些方法依赖于心电数据的数字版本,而在实践中,许多心电数据仍然以纸质形式存在。因此,现有的机器学习诊断模型在实际场景中的准确性是次优的。为了提高机器学习模型诊断心肌病的准确性,我们提出了一种能够诊断HCM和DCM的多模态机器学习模型。方法:采用人工神经网络(ANN)对超声心动图报表和生化检查数据进行特征提取。此外,利用卷积神经网络(CNN)对心电图(ECG)进行特征提取。结果提取的特征随后被整合并输入到多层感知器(MLP)中进行诊断分类。结果:多模态融合模型的准确率为89.87%,召回率为91.20%,F1评分为89.13%,准确率为89.72%。结论:与现有的机器学习模型相比,我们提出的多模态融合模型在各种性能指标上取得了更好的结果。我们相信我们的方法是有效的。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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