Daily functioning in glioma survivors: associations with cognitive function, psychological factors and quality of life.

Q1 Medicine CNS Oncology Pub Date : 2022-06-01 Epub Date: 2022-05-18 DOI:10.2217/cns-2022-0002
Kathleen Van Dyk, Lucy Wall, Brandon F Heimberg, Justin Choi, Catalina Raymond, Chencai Wang, Albert Lai, Timothy F Cloughesy, Benjamin M Ellingson, Phioanh Nghiemphu
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Abstract

Aim: Understanding and supporting quality of life (QoL) and daily functioning in glioma patients is a clinical imperative. In this study, we examined the relationship between cognition, psychological factors, measures of health-related QoL and functioning in glioma survivors. Materials & methods: We examined neuropsychological, self-reported cognition, mood and QoL correlates of work and non-work-related daily functioning in 23 glioma survivors, and carried out linear models of the best predictors. Results & conclusion: A total of 13/23 participants were working at the time of enrollment. The best model for worse work-related functioning (R2 = .83) included worse self-reported cognitive function, depression, loneliness and brain tumor symptoms. The best model for worse non-work-related functioning (R2 = .61) included worse self-reported cognitive functioning, anxiety, sleep disturbance and physical functioning. Neuropsychological variables were not among the most highly correlated with function. Worse cognitive, particularly self-reported and psychosocial outcomes may compromise optimal functioning in glioma survivors.

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胶质瘤幸存者的日常功能:与认知功能、心理因素和生活质量的关系。
目的:了解和支持胶质瘤患者的生活质量(QoL)和日常功能是临床的当务之急。在这项研究中,我们探讨了胶质瘤幸存者的认知、心理因素、健康相关 QoL 测量和功能之间的关系。材料与方法:我们研究了 23 名胶质瘤幸存者的神经心理学、自我报告的认知、情绪以及与工作和非工作相关的日常功能的 QoL 相关性,并对最佳预测因素进行了线性建模。结果与结论共有 13/23 名参与者在入组时有工作。与工作相关的功能变差的最佳模型(R2 = 0.83)包括自我报告的认知功能变差、抑郁、孤独和脑肿瘤症状。非工作相关功能变差的最佳模型(R2 = 0.61)包括自我报告的认知功能、焦虑、睡眠障碍和身体功能变差。神经心理学变量与功能的相关性并不高。较差的认知功能,尤其是自我报告的功能和心理社会功能可能会影响胶质瘤幸存者的最佳功能。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CNS Oncology
CNS Oncology Medicine-Neurology (clinical)
CiteScore
3.80
自引率
0.00%
发文量
12
审稿时长
13 weeks
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