Mechanisms underlying the Effects of Heat Stress on Intestinal Integrity, Inflammation, and Microbiota in Chickens.

IF 1.8 4区 农林科学 Q2 AGRICULTURE, DAIRY & ANIMAL SCIENCE Journal of Poultry Science Pub Date : 2023-01-01 DOI:10.2141/jpsa.2023021
Motoi Kikusato, Masaaki Toyomizu
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引用次数: 1

Abstract

Poultry meat and egg production benefits from a smaller carbon footprint, as well as feed and water consumption, per unit of product, than other protein sources. Therefore, maintaining a sustainable production of poultry meat is important to meet the increasing global demand for this staple. Heat stress experienced during the summer season or in tropical/subtropical areas negatively affects the productivity and health of chickens. Crucially, its impact is predicted to grow with the acceleration of global warming. Heat stress affects the physiology, metabolism, and immune response of chickens, causing electrolyte imbalance, oxidative stress, endocrine disorders, inflammation, and immunosuppression. These changes do not occur independently, pointing to a systemic mechanism. Recently, intestinal homeostasis has been identified as an important contributor to nutrient absorption and the progression of systemic inflammation. Its mechanism of action is thought to involve neuroendocrine signaling, antioxidant response, the presence of oxidants in the diet, and microbiota composition. The present review focuses on the effect of heat stress on intestinal dysfunction in chickens and the underlying causative factors. Understanding these mechanisms will direct the design of strategies to mitigate the negative effect of heat stress, while benefiting both animal health and sustainable poultry production.

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热应激对鸡肠道完整性、炎症和微生物群影响的机制。
与其他蛋白质来源相比,禽肉和禽蛋生产的好处在于碳足迹更小,单位产品的饲料和水消耗也更少。因此,保持禽肉的可持续生产对于满足全球对这种主食日益增长的需求至关重要。在夏季或热带/亚热带地区经历的热应激对鸡的生产力和健康产生负面影响。至关重要的是,预计其影响将随着全球变暖的加速而增长。热应激会影响鸡的生理、代谢和免疫反应,引起电解质失衡、氧化应激、内分泌紊乱、炎症和免疫抑制。这些变化不是独立发生的,表明存在系统性机制。最近,肠道内稳态已被确定为营养吸收和全身性炎症进展的重要贡献者。其作用机制被认为与神经内分泌信号、抗氧化反应、饮食中氧化剂的存在和微生物群组成有关。本文就热应激对鸡肠道功能障碍的影响及其相关因素进行综述。了解这些机制将指导策略的设计,以减轻热应激的负面影响,同时有利于动物健康和可持续家禽生产。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Poultry Science
Journal of Poultry Science AGRICULTURE, DAIRY & ANIMAL SCIENCE-
CiteScore
2.80
自引率
13.30%
发文量
26
审稿时长
12 months
期刊介绍: The Journal of Poultry Science will publish original reports and reviews which either make an original contribution to fundamental science or are of obvious application to the industry. Subjects which are covered include: breeding and genetics, nutrition and feeds, physiology, reproduction, immunology, behavior, environmental science, management and housing welfare, processing and products, and health in poultry. Submission of original articles to the Journal is open to all poultry researchers. The review articles are invited papers written by international outstanding researchers. Articles will be published in English, American style.
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