Julian Chipukuma, Brianna Lindsay, Linah K Mwango, Pawel Olowski, Caitlin Baumhart, Kalima Tembo, Adebayo A Olufunso, Christine Bwale, Priscilla Makasa, Monde Muchoka, Salina Tembo, Waitolo Mbokile, Comfort Panda, Siphiwe Malupande, Richard Lubinda, Brenda Bwembelo, Everess Fundulu, Chimpinde Munsongo, Kelvin Watala, Bupe Musonda, Omega Chituwo, Jackson Okuku, Annie Mwila, Carlos Muleya, Pragna Patel, Cassidy W Claassen
{"title":"通过赞比亚四个地区的 DREAMS 计划，促进 16-24 岁艾滋病高危少女和年轻女性获得 PrEP。","authors":"Julian Chipukuma, Brianna Lindsay, Linah K Mwango, Pawel Olowski, Caitlin Baumhart, Kalima Tembo, Adebayo A Olufunso, Christine Bwale, Priscilla Makasa, Monde Muchoka, Salina Tembo, Waitolo Mbokile, Comfort Panda, Siphiwe Malupande, Richard Lubinda, Brenda Bwembelo, Everess Fundulu, Chimpinde Munsongo, Kelvin Watala, Bupe Musonda, Omega Chituwo, Jackson Okuku, Annie Mwila, Carlos Muleya, Pragna Patel, Cassidy W Claassen","doi":"10.1521/aeap.2023.35.suppA.52","DOIUrl":null,"url":null,"abstract":"<p><p>Adolescent girls and young women (AGYW) in sub-Saharan Africa remain at high risk for HIV, yet limited data exist on implementation of HIV pre-exposure prophylaxis (PrEP) for this group. We examined PrEP uptake among AGYW using a retrospective cohort enrolled in the Determined Resilient Empowered AIDS-free Mentored Safe (DREAMS) initiative in Zambia between October 2020 and March 2022. Consent was obtained from eligible AGYW at substantial risk for HIV, and they voluntarily participated in PrEP. Multivariable logistic regression was used to examine factors associated with PrEP refills following initiation. Of 4,162 HIV-negative AGYW, 3,233 (77%) were at substantial risk and initiated on PrEP. Overall, 68% of AGYW had at least one refill, but this differed significantly by age group and district. DREAMS was successful at reaching AGYW with PrEP services. More evidence is needed to assess reasons for discontinuation and to improve persistence for those with sustained HIV risk.</p>","PeriodicalId":47801,"journal":{"name":"Aids Education and Prevention","volume":null,"pages":null},"PeriodicalIF":1.6000,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10764235/pdf/","citationCount":"0","resultStr":"{\"title\":\"Fostering Access to PrEP Among Adolescent Girls and Young Women Aged 16 to 24 Years at High Risk of HIV Through the DREAMS Initiative in Four Districts in Zambia.\",\"authors\":\"Julian Chipukuma, Brianna Lindsay, Linah K Mwango, Pawel Olowski, Caitlin Baumhart, Kalima Tembo, Adebayo A Olufunso, Christine Bwale, Priscilla Makasa, Monde Muchoka, Salina Tembo, Waitolo Mbokile, Comfort Panda, Siphiwe Malupande, Richard Lubinda, Brenda Bwembelo, Everess Fundulu, Chimpinde Munsongo, Kelvin Watala, Bupe Musonda, Omega Chituwo, Jackson Okuku, Annie Mwila, Carlos Muleya, Pragna Patel, Cassidy W Claassen\",\"doi\":\"10.1521/aeap.2023.35.suppA.52\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Adolescent girls and young women (AGYW) in sub-Saharan Africa remain at high risk for HIV, yet limited data exist on implementation of HIV pre-exposure prophylaxis (PrEP) for this group. We examined PrEP uptake among AGYW using a retrospective cohort enrolled in the Determined Resilient Empowered AIDS-free Mentored Safe (DREAMS) initiative in Zambia between October 2020 and March 2022. Consent was obtained from eligible AGYW at substantial risk for HIV, and they voluntarily participated in PrEP. Multivariable logistic regression was used to examine factors associated with PrEP refills following initiation. Of 4,162 HIV-negative AGYW, 3,233 (77%) were at substantial risk and initiated on PrEP. Overall, 68% of AGYW had at least one refill, but this differed significantly by age group and district. DREAMS was successful at reaching AGYW with PrEP services. More evidence is needed to assess reasons for discontinuation and to improve persistence for those with sustained HIV risk.</p>\",\"PeriodicalId\":47801,\"journal\":{\"name\":\"Aids Education and Prevention\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2023-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10764235/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Aids Education and Prevention\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1521/aeap.2023.35.suppA.52\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"EDUCATION & EDUCATIONAL RESEARCH\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Aids Education and Prevention","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1521/aeap.2023.35.suppA.52","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"EDUCATION & EDUCATIONAL RESEARCH","Score":null,"Total":0}
Fostering Access to PrEP Among Adolescent Girls and Young Women Aged 16 to 24 Years at High Risk of HIV Through the DREAMS Initiative in Four Districts in Zambia.
Adolescent girls and young women (AGYW) in sub-Saharan Africa remain at high risk for HIV, yet limited data exist on implementation of HIV pre-exposure prophylaxis (PrEP) for this group. We examined PrEP uptake among AGYW using a retrospective cohort enrolled in the Determined Resilient Empowered AIDS-free Mentored Safe (DREAMS) initiative in Zambia between October 2020 and March 2022. Consent was obtained from eligible AGYW at substantial risk for HIV, and they voluntarily participated in PrEP. Multivariable logistic regression was used to examine factors associated with PrEP refills following initiation. Of 4,162 HIV-negative AGYW, 3,233 (77%) were at substantial risk and initiated on PrEP. Overall, 68% of AGYW had at least one refill, but this differed significantly by age group and district. DREAMS was successful at reaching AGYW with PrEP services. More evidence is needed to assess reasons for discontinuation and to improve persistence for those with sustained HIV risk.
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Presenting state-of-the-art research and information, AIDS Education and Prevention is a vital addition to the library collections of medical schools, hospitals, and other institutions and organizations with HIV/AIDS research programs. The journal integrates public health, psychosocial, sociocultural, and public policy perspectives on issues of key concern nationally and globally.
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