再生医学改善神经退行性疾病。

IF 1.4 4区 医学 Q4 CELL BIOLOGY Cell and Tissue Banking Pub Date : 2023-09-01 DOI:10.1007/s10561-022-10062-0
Seyedeh Sara Ashraf, Vahid Hosseinpour Sarmadi, Ghazaleh Larijani, Soheila Naderi Garahgheshlagh, Sara Ramezani, Soraya Moghadamifar, Seyedeh Lena Mohebi, Peiman Brouki Milan, Seyed Mohammad Amin Haramshahi, Nooshin Ahmadirad, Naser Amini
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引用次数: 3

摘要

再生医学是医学的一个分支,它改进了再生、修复或替换不健康细胞和组织以恢复正常功能的方法。细胞疗法、基因疗法、纳米药物作为治疗神经退行性疾病的选择。近年来,除再生医学外,神经退行性疾病的治疗研究主要集中在干细胞治疗和纳米药物方面。因此,通过实验模型和临床试验的数据,我们回顾了干细胞治疗、基因治疗和纳米药物对阿尔茨海默病(AD)、帕金森病(PD)和肌萎缩侧索硬化症(ALS)治疗的影响。事实上,在治疗阿尔茨海默病、帕金森氏病和肌萎缩侧索硬化症的基因治疗和纳米药物方面,知识的提高和持续研究导致了神经退行性疾病的有效和实用治疗的进步。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Regenerative medicine improve neurodegenerative diseases.

Regenerative medicine is a subdivision of medicine that improves methods to regrow, repair or replace unhealthy cells and tissues to return to normal function. Cell therapy, gene therapy, nanomedicine as choices used to cure neurodegenerative disease. Recently, studies related to the treatment of neurodegenerative disorders have been focused on stem cell therapy and Nano-drugs beyond other than regenerative medicine. Hence, by data from experimental models and clinical trials, we review the impact of stem cell therapy, gene therapy, and nanomedicine on the treatment of Alzheimer's disease (AD), Parkinson's disease (PD), and Amyotrophic lateral sclerosis (ALS). Indeed, improved knowledge and continued research on gene therapy and nanomedicine in treating Alzheimer's disease, Parkinson's disease, and Amyotrophic lateral sclerosis lead to advancements in effective and practical treatments for neurodegenerative diseases.

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来源期刊
Cell and Tissue Banking
Cell and Tissue Banking CELL BIOLOGY-ENGINEERING, BIOMEDICAL
CiteScore
3.10
自引率
13.30%
发文量
68
审稿时长
6-12 weeks
期刊介绍: Cell and Tissue Banking provides a forum for disseminating information to scientists and clinicians involved in the banking and transplantation of cells and tissues. Cell and Tissue Banking is an international, peer-reviewed journal that publishes original papers in the following areas: basic research concerning general aspects of tissue banking such as quality assurance and control of banked cells/tissues, effects of preservation and sterilisation methods on cells/tissues, biotechnology, etc.; clinical applications of banked cells/tissues; standards of practice in procurement, processing, storage and distribution of cells/tissues; ethical issues; medico-legal issues.
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