前颞叶切除对皮质形态的影响

IF 3.2 2区 心理学 Q1 BEHAVIORAL SCIENCES Cortex Pub Date : 2023-09-01 DOI:10.1016/j.cortex.2023.04.018
Karoline Leiberg , Jane de Tisi , John S. Duncan , Bethany Little , Peter N. Taylor , Sjoerd B. Vos , Gavin P. Winston , Bruno Mota , Yujiang Wang
{"title":"前颞叶切除对皮质形态的影响","authors":"Karoline Leiberg ,&nbsp;Jane de Tisi ,&nbsp;John S. Duncan ,&nbsp;Bethany Little ,&nbsp;Peter N. Taylor ,&nbsp;Sjoerd B. Vos ,&nbsp;Gavin P. Winston ,&nbsp;Bruno Mota ,&nbsp;Yujiang Wang","doi":"10.1016/j.cortex.2023.04.018","DOIUrl":null,"url":null,"abstract":"<div><p>Neuroimaging can capture brain restructuring after anterior temporal lobe resection (ATLR), a surgical procedure to treat drug-resistant temporal lobe epilepsy (TLE). Here, we examine the effects of this surgery on brain morphology measured in recently-proposed independent variables.</p><p>We studied 101 individuals with TLE (55 left, 46 right onset) who underwent ATLR. For each individual we considered one pre-surgical MRI and one follow-up MRI 2–13 months after surgery. We used a surface-based method to locally compute traditional morphological variables, and the independent measures <em>K</em>, <em>I</em>, and <em>S</em>, where <em>K</em> measures white matter tension, <em>I</em> captures isometric scaling, and <em>S</em> contains the remaining information about cortical shape. A normative model trained on data from 924 healthy controls was used to debias the data and account for healthy ageing effects occurring during scans. A SurfStat random field theory clustering approach assessed changes across the cortex caused by ATLR.</p><p>Compared to preoperative data, surgery had marked effects on all morphological measures. Ipsilateral effects were located in the orbitofrontal and inferior frontal gyri, the pre- and postcentral gyri and supramarginal gyrus, and the lateral occipital gyrus and lingual cortex. Contralateral effects were in the lateral occipital gyrus, and inferior frontal gyrus and frontal pole.</p><p>The restructuring following ATLR is reflected in widespread morphological changes, mainly in regions near the resection, but also remotely in regions that are structurally connected to the anterior temporal lobe. The causes could include mechanical effects, Wallerian degeneration, or compensatory plasticity. The study of independent measures revealed additional effects compared to traditional measures.</p></div>","PeriodicalId":10758,"journal":{"name":"Cortex","volume":"166 ","pages":"Pages 233-242"},"PeriodicalIF":3.2000,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Effects of anterior temporal lobe resection on cortical morphology\",\"authors\":\"Karoline Leiberg ,&nbsp;Jane de Tisi ,&nbsp;John S. Duncan ,&nbsp;Bethany Little ,&nbsp;Peter N. Taylor ,&nbsp;Sjoerd B. Vos ,&nbsp;Gavin P. Winston ,&nbsp;Bruno Mota ,&nbsp;Yujiang Wang\",\"doi\":\"10.1016/j.cortex.2023.04.018\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Neuroimaging can capture brain restructuring after anterior temporal lobe resection (ATLR), a surgical procedure to treat drug-resistant temporal lobe epilepsy (TLE). Here, we examine the effects of this surgery on brain morphology measured in recently-proposed independent variables.</p><p>We studied 101 individuals with TLE (55 left, 46 right onset) who underwent ATLR. For each individual we considered one pre-surgical MRI and one follow-up MRI 2–13 months after surgery. We used a surface-based method to locally compute traditional morphological variables, and the independent measures <em>K</em>, <em>I</em>, and <em>S</em>, where <em>K</em> measures white matter tension, <em>I</em> captures isometric scaling, and <em>S</em> contains the remaining information about cortical shape. A normative model trained on data from 924 healthy controls was used to debias the data and account for healthy ageing effects occurring during scans. A SurfStat random field theory clustering approach assessed changes across the cortex caused by ATLR.</p><p>Compared to preoperative data, surgery had marked effects on all morphological measures. Ipsilateral effects were located in the orbitofrontal and inferior frontal gyri, the pre- and postcentral gyri and supramarginal gyrus, and the lateral occipital gyrus and lingual cortex. Contralateral effects were in the lateral occipital gyrus, and inferior frontal gyrus and frontal pole.</p><p>The restructuring following ATLR is reflected in widespread morphological changes, mainly in regions near the resection, but also remotely in regions that are structurally connected to the anterior temporal lobe. The causes could include mechanical effects, Wallerian degeneration, or compensatory plasticity. The study of independent measures revealed additional effects compared to traditional measures.</p></div>\",\"PeriodicalId\":10758,\"journal\":{\"name\":\"Cortex\",\"volume\":\"166 \",\"pages\":\"Pages 233-242\"},\"PeriodicalIF\":3.2000,\"publicationDate\":\"2023-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cortex\",\"FirstCategoryId\":\"102\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0010945223001351\",\"RegionNum\":2,\"RegionCategory\":\"心理学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"BEHAVIORAL SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cortex","FirstCategoryId":"102","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0010945223001351","RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BEHAVIORAL SCIENCES","Score":null,"Total":0}
引用次数: 0

摘要

神经成像可以捕捉颞叶前叶切除术(ATLR)后的大脑重构,这是一种治疗耐药颞叶癫痫(TLE)的外科手术。在这里,我们研究了这种手术对最近提出的自变量测量的大脑形态的影响。我们研究了101例接受ATLR的TLE患者(55例左起,46例右起)。对于每个个体,我们考虑了一次术前MRI和一次术后2-13个月的随访MRI。我们使用基于表面的方法来局部计算传统的形态学变量,独立测量K、I和S,其中K测量白质张力,I捕捉等距缩放,S包含关于皮层形状的剩余信息。使用根据924名健康对照的数据训练的标准模型对数据进行去噪,并说明扫描过程中发生的健康衰老影响。SurfsStat随机场论聚类方法评估了ATLR引起的整个皮层的变化。与术前数据相比,手术对所有形态学指标都有显著影响。同侧效应位于眶额回和额下回、中央前回和中央后回和缘上回、枕外侧回和舌皮质。对侧效应发生在枕外侧回、额下回和额极。ATLR后的重组反映在广泛的形态学变化中,主要在切除附近的区域,但也在结构上与颞前叶相连的区域。原因可能包括机械效应、Wallerian变性或代偿性可塑性。对独立措施的研究揭示了与传统措施相比的额外效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Effects of anterior temporal lobe resection on cortical morphology

Neuroimaging can capture brain restructuring after anterior temporal lobe resection (ATLR), a surgical procedure to treat drug-resistant temporal lobe epilepsy (TLE). Here, we examine the effects of this surgery on brain morphology measured in recently-proposed independent variables.

We studied 101 individuals with TLE (55 left, 46 right onset) who underwent ATLR. For each individual we considered one pre-surgical MRI and one follow-up MRI 2–13 months after surgery. We used a surface-based method to locally compute traditional morphological variables, and the independent measures K, I, and S, where K measures white matter tension, I captures isometric scaling, and S contains the remaining information about cortical shape. A normative model trained on data from 924 healthy controls was used to debias the data and account for healthy ageing effects occurring during scans. A SurfStat random field theory clustering approach assessed changes across the cortex caused by ATLR.

Compared to preoperative data, surgery had marked effects on all morphological measures. Ipsilateral effects were located in the orbitofrontal and inferior frontal gyri, the pre- and postcentral gyri and supramarginal gyrus, and the lateral occipital gyrus and lingual cortex. Contralateral effects were in the lateral occipital gyrus, and inferior frontal gyrus and frontal pole.

The restructuring following ATLR is reflected in widespread morphological changes, mainly in regions near the resection, but also remotely in regions that are structurally connected to the anterior temporal lobe. The causes could include mechanical effects, Wallerian degeneration, or compensatory plasticity. The study of independent measures revealed additional effects compared to traditional measures.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Cortex
Cortex 医学-行为科学
CiteScore
7.00
自引率
5.60%
发文量
250
审稿时长
74 days
期刊介绍: CORTEX is an international journal devoted to the study of cognition and of the relationship between the nervous system and mental processes, particularly as these are reflected in the behaviour of patients with acquired brain lesions, normal volunteers, children with typical and atypical development, and in the activation of brain regions and systems as recorded by functional neuroimaging techniques. It was founded in 1964 by Ennio De Renzi.
期刊最新文献
Shared body representation constraints in human and non-human primates behavior Exploring the development of past and future episodic memory in adolescents with autism spectrum disorder: A preliminary longitudinal study Vertical neglect towards the lower space after bilateral parietal strokes – A case study Diminished sense of agency inhibits paretic upper-limb use in patients with post-stroke motor deficits EEG frequency tagging reveals the integration of dissimilar observed actions.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1