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Discourse abilities in post-stroke aphasia: A multi-level analysis of macro and micro-structural discourse properties and their white matter neural correlates 脑卒中后失语症的话语能力:宏观和微观结构话语特征及其白质神经关联的多层次分析。
IF 3.3 2区 心理学 Q1 BEHAVIORAL SCIENCES Pub Date : 2026-01-02 DOI: 10.1016/j.cortex.2025.12.005
Belle Jacobs , Guillem Olivé , Immaculada Rico-Pons , Antoni Rodríguez-Fornells , Claudia Peñaloza
Although it is well established that discourse abilities are often impaired in people with aphasia (PWA), research and assessment methods addressing spoken discourse in Spanish-speaking PWA are limited. Moreover, the white matter underpinnings of discourse production in aphasia are understudied, calling for their comprehensive examination across both macro and micro-structural levels. The present study developed a Spanish main concept (MC) checklist for the Cookie Theft picture description task to assess discourse informativeness abilities in Spanish-speaking PWA. We used this task to evaluate discourse performance in 19 Spanish-speaking PWA relative to 37 neurotypical controls as per macro-structural and micro-structural discourse metrics. The association between discourse performance and aphasia severity as well as brain structural connectivity as per bilateral language-related white matter tract volumes and fractional anisotropy values were investigated in PWA. Our Spanish MC checklist for the Cookie Theft resulted in 7 MCs largely consistent with previous research. We found that PWA performed significantly below the neurotypical controls in most discourse metrics. Aphasia severity was associated with the number of verbs produced in picture description. The volumes of the left Arcuate Fasciculus (posterior segment) and the right Inferior Longitudinal Fasciculus were associated with micro- and macro-structural metrics of discourse performance, respectively. Our findings suggest that white matter structural connectivity in the left and the right hemisphere may differentially support linguistic and functional aspects of discourse ability in chronic aphasia.
虽然人们普遍认为,失语症患者的话语能力往往受损,但针对西班牙语失语症患者口语话语的研究和评估方法有限。此外,失语症中话语产生的白质基础尚未得到充分研究,需要从宏观和微观结构两个层面对其进行综合研究。本研究开发了一个西班牙语主概念(MC)检查表,用于评估西班牙语PWA的语篇信息性能力。根据宏观结构和微观结构话语指标,我们使用这个任务来评估19名讲西班牙语的PWA相对于37名神经正常对照的话语表现。根据双侧语言相关白质束体积和分数各向异性值,研究言语表现与失语严重程度以及脑结构连通性之间的关系。我们对Cookie盗窃的西班牙MC清单得出了7个MC,与之前的研究基本一致。我们发现PWA在大多数话语指标上的表现明显低于神经典型对照组。失语症的严重程度与图片描述中出现的动词数量有关。左侧弓状束(后段)和右侧下纵束的体积分别与话语表现的微观和宏观结构指标相关。我们的研究结果表明,在慢性失语症中,左右脑白质结构的连通性可能在语言和话语能力的功能方面有不同的支持。
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引用次数: 0
Cover figure 封面图
IF 3.3 2区 心理学 Q1 BEHAVIORAL SCIENCES Pub Date : 2026-01-01 DOI: 10.1016/S0010-9452(25)00325-9
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引用次数: 0
The relationship between language disorder and thought disorder: Comparing micro- and macrostructure of spoken narratives of people with aphasia and people with schizophrenia 语言障碍与思维障碍的关系:失语症患者与精神分裂症患者言语叙事的微观与宏观结构比较
IF 3.3 2区 心理学 Q1 BEHAVIORAL SCIENCES Pub Date : 2025-12-31 DOI: 10.1016/j.cortex.2025.12.006
Vitor Zimmerer , Andromachi Tsoukala , Derya Çokal , Gabriel Sevilla , Maggie Douglas , Will Jones , I. Nicol Ferrier , Douglas Turkington , Stuart Watson , Rosemary Varley , Wolfram Hinzen
Linguistic profiles in neurological and psychiatric conditions offer critical insights into the relationship between language and broader cognitive functions. People with aphasia (PwA) can display severe language production and comprehension difficulties, often alongside relatively preserved capacity in other domains. In contrast, people with schizophrenia (PwS) can present with disordered thoughts, delusions and hallucinations, accompanied by atypical language use. We examined microstructural (lexicon, syntax) and macrostructural (narrative) features of comic strip descriptions produced by PwA, PwS, and two respective control samples, using manual annotation and computerized tools. Both clinical groups diverged from controls at microstructural and macrostructural levels. However, PwA showed greater microstructural disruption, while PwS exhibited greater macrostructural impairment. Language production in PwA differed most from PwS in the much higher rate of morphosyntactic errors, more frequent intra-clausal pauses, and a greater reduction of grammatical complexity. In PwA, performance in non-verbal reasoning and semantics tests correlated with macrostructural, but not with microstructural measures. In PwS, non-verbal reasoning scores correlated with both micro- and macrostructural measures. These findings highlight distinct effects of more focal left perisylvian damage associated with aphasia, versus diffuse bihemispheric frontotemporal and parietal dysfunction associated with schizophrenia, on cognition and communication. We propose that verbal disruption with few morphosyntactic errors and intra-clausal pauses reflects broader cognitive dysfunction, whereas a high frequency of these features points to difficulties more specific to language production and comprehension.
神经和精神疾病的语言概况为语言与更广泛的认知功能之间的关系提供了重要的见解。失语症患者可能表现出严重的语言产生和理解困难,同时在其他领域也有相对保留的能力。相比之下,精神分裂症(PwS)患者可能表现为思维紊乱、妄想和幻觉,并伴有非典型的语言使用。我们使用手工注释和计算机化工具,研究了由PwA、PwS和两个各自的对照样本制作的漫画描述的微观结构(词汇、语法)和宏观结构(叙事)特征。两个临床组在微观结构和宏观结构水平上都与对照组不同。然而,PwA表现出更大的微观结构破坏,而PwS表现出更大的宏观结构损伤。PwA的语言产生与PwS的差异最大的是形态句法错误率高得多,更频繁的小句内停顿,以及语法复杂性的更大降低。在PwA中,非语言推理和语义测试的表现与宏观结构相关,而与微观结构测试无关。在PwS中,非言语推理得分与微观和宏观结构测量都相关。这些发现强调了与失语症相关的更多局灶性左外半球损伤,与精神分裂症相关的弥漫性双脑额颞叶和顶叶功能障碍相比,对认知和交流的不同影响。我们认为,很少有形态句法错误和小句内停顿的言语中断反映了更广泛的认知功能障碍,而这些特征的高频率则表明语言产生和理解的困难更为具体。
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引用次数: 0
Anodal transcranial direct current stimulation over the right inferior frontal gyrus enhances inhibitory control, with modulation by individual differences in metacognition and delay discounting 经颅阳极直流电刺激右额下回增强抑制控制,并受元认知和延迟折扣的个体差异调节
IF 3.3 2区 心理学 Q1 BEHAVIORAL SCIENCES Pub Date : 2025-12-30 DOI: 10.1016/j.cortex.2025.11.016
Mattia Ferro , Daniele Saccenti , Andrea Stefano Moro , Francesca Ceruti , Paola de Bartolo , Sandra Sassaroli , Antonio Malgaroli , Jacopo Lamanna
Inhibitory control is a fundamental component of executive functioning, enabling the suppression of one's own cognitive and behavioral responses. Although inhibitory control exerts substantial effects on everyday life and clinical settings, its neural underpinnings and relationship with other higher-order cognitive functions remain poorly understood. The right inferior frontal gyrus (rIFG) has been proposed as a potential target for neuromodulation, given its putative role in the inhibition of premature or maladaptive motor responses. In this study, we applied transcranial direct current stimulation (tDCS) over the rIFG in thirty one healthy participants, each undergoing two experimental sessions—one with active stimulation and one with sham stimulation. Prior to stimulation, participants completed the Metacognitions Questionnaire-30 and a Monetary Intertemporal Choice Task (MICT) to assess delay discounting. During stimulation, subjects performed the Go/NoGo and the Stop-Signal tasks to evaluate inhibitory control. Following stimulation, they repeated the MICT. Our results show that anodal tDCS over the rIFG enhances inhibitory control compared to sham stimulation. Significant interaction effects on inhibitory control were also observed between tDCS protocol and baseline measures of metacognitive beliefs and delay discounting. Although rIFG stimulation did not steeply reduce delay discounting, significant time-by-protocol and metacognition-by-protocol interactions were detected. These findings not only suggest that tDCS effects on inhibitory control are affected by subjects' cognitive profiles but also pave the way for future research on the efficacy of tDCS in enhancing inhibitory control and reducing delay discounting in psychological conditions where these higher-order cognitive functions are impaired, such as mood disorders and substance addiction.
抑制性控制是执行功能的基本组成部分,能够抑制自己的认知和行为反应。尽管抑制控制在日常生活和临床环境中发挥着重要作用,但其神经基础及其与其他高阶认知功能的关系仍然知之甚少。右额下回(rIFG)被认为是神经调节的潜在靶点,因为它在抑制过早或适应性不良的运动反应中起着假定的作用。本研究采用经颅直流电刺激(tDCS)对31名健康受试者进行了两组实验,分别为主动刺激和假刺激。在刺激之前,参与者完成了元认知问卷-30和货币跨期选择任务(MICT)来评估延迟贴现。在刺激过程中,受试者执行Go/NoGo和Stop-Signal任务来评估抑制控制。在刺激之后,他们重复了MICT。我们的研究结果表明,与假刺激相比,阳极tDCS在rIFG上增强了抑制控制。在抑制控制方面,tDCS方案与元认知信念和延迟折扣的基线测量之间也观察到显著的交互作用。虽然刺激rIFG并没有显著降低延迟折扣,但我们发现了显著的按协议时间和按协议元认知的相互作用。这些发现不仅表明tDCS对抑制控制的作用受到受试者认知特征的影响,而且为进一步研究tDCS在情绪障碍和物质成瘾等高阶认知功能受损的心理条件下增强抑制控制和减少延迟折扣的作用铺平了道路。
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引用次数: 0
Measuring brain sensitivity to semantic distance in spoken narrative comprehension 口语叙事理解中脑对语义距离敏感性的测量。
IF 3.3 2区 心理学 Q1 BEHAVIORAL SCIENCES Pub Date : 2025-12-17 DOI: 10.1016/j.cortex.2025.12.004
Hannah Mechtenberg , Jamie Reilly , Jonathan E. Peelle , Emily B. Myers
Discourse comprehension requires simultaneous integration of local and global constituents. When hearing a narrative, for example, listeners must link the meaning of each incoming word to the preceding word (local context) while also assimilating its meaning into the broader gist of a story (global context). Thus, the brain simultaneously constructs meaning at different time scales and with different levels of granularity. Our understanding of the brain's division of labor in processing local versus global semantic distance relationships is limited. In this study we ask specifically how the semantic distance between a word and its prior context drives activity in the brain during naturalistic listening. We used fMRI data collected while participants (n = 79) listened to a podcast interview. Using a novel method for estimating semantic distance between a word and prior contexts computed at multiple grain sizes, we conducted an amplitude-modulated regression to identify brain regions that were sensitive to semantic distance. Results show that semantic distance drives activation in a broad frontotemporal network including the left and right superior and middle temporal gyrus and left inferior frontal gyrus, as well as the bilateral cerebellum. The right anterior superior temporal gyrus was particularly sensitive to the increase in context window size, consistent with a right hemisphere specialization for gist processing and for the anterior temporal lobes' purported role in semantic integration. This study demonstrates a promising method for investigating neural sensitivity to semantic movement in naturalistic language.
话语理解需要同时整合本地和全球成分。例如,在听叙述时,听众必须将每个进入的单词的意思与前面的单词联系起来(当地语境),同时也要将其意思吸收到故事的更广泛的要点中(全球语境)。因此,大脑在不同的时间尺度和不同的粒度水平上同时构建意义。我们对大脑在处理局部和全局语义距离关系中的分工的理解是有限的。在这项研究中,我们具体地询问了在自然聆听过程中,单词与其先前上下文之间的语义距离是如何驱动大脑活动的。我们使用在参与者(n = 79)听播客采访时收集的功能磁共振成像数据。我们使用一种新的方法来估计在多个粒度下计算的单词和先前上下文之间的语义距离,我们进行了调幅回归来识别对语义距离敏感的大脑区域。结果表明,语义距离驱动了包括左右颞上回和中回、左额下回以及双侧小脑在内的广泛额颞网络的激活。右前颞上回对上下文窗口大小的增加特别敏感,这与右半球专门处理主旨和前颞叶在语义整合中的作用是一致的。本研究为研究自然语言语义运动的神经敏感性提供了一种有前景的方法。
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引用次数: 0
Relationships between gaze behaviour and fencing performance of high-skilled fencing athletes: Perspectives from defensive and offensive phases 高技术击剑运动员注视行为与击剑成绩的关系:来自防守和进攻阶段的视角。
IF 3.3 2区 心理学 Q1 BEHAVIORAL SCIENCES Pub Date : 2025-12-13 DOI: 10.1016/j.cortex.2025.12.003
Andrada Vincze , Andra Felicia Gabriela Iacob , Ioana Radu , Dragoş Iliescu , Răzvan Jurchiş
This study explores the relationship between visual processing and fencing performance, focusing on various gaze behaviour indices in a dynamic and interactive sport. Visual processing, particularly the ability to gather and use visual information quickly and accurately, is critical for performance in high-speed sports. We hypothesised that visual behaviour, including the duration of the final fixation (Quiet Eye; QE), the number of fixations and the number of scanned locations, significantly impacts fencing performance during offensive and defensive actions. National-level sabre fencers performed a 10-min assault with eye-tracking technology measuring their gaze behaviour. Results indicated that QE was significantly longer before successful touches compared to unsuccessful ones (Bayes factor (B) = 30.92). Additionally, the number of fixations and the number of scanned locations were higher during defensive actions than offensive actions (all Bs ≥ 1908.99). This research provides insights into the cognitive processes underlying sports performance in a realistic context and has implications for training strategies, emphasising the importance of various visual behaviour patterns in fencing.
本研究探讨了视觉加工与击剑表现之间的关系,重点关注动态互动运动中的各种凝视行为指数。视觉处理,特别是快速准确地收集和使用视觉信息的能力,对于高速运动的表现至关重要。我们假设视觉行为,包括最终注视的持续时间(静眼;QE),注视的次数和扫描位置的数量,在进攻和防御行动中显著影响击剑的表现。国家级佩剑运动员进行了10分钟的攻击,用眼球追踪技术测量他们的凝视行为。结果表明,与不成功的触摸相比,QE在成功触摸前的时间明显更长(贝叶斯因子(B) = 30.92)。此外,防守动作的注视数和扫描位置数均高于进攻动作(b值均≥1988.99)。这项研究提供了在现实背景下运动表现的认知过程的见解,并对训练策略有启示,强调了击剑中各种视觉行为模式的重要性。
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引用次数: 0
Using EEG to detect lapses in sustained attention to moving stimuli 利用脑电图检测对运动刺激持续注意的缺失
IF 3.3 2区 心理学 Q1 BEHAVIORAL SCIENCES Pub Date : 2025-12-11 DOI: 10.1016/j.cortex.2025.12.002
Benjamin G. Lowe , Alexandra Woolgar , Sophie Smit , Anina N. Rich
Sustaining attention is effortful but crucial for daily life. Despite this, attentional lapses are common and can have fatal consequences (e.g., when driving). The spontaneous nature of these lapses makes studying their underlying phenomena elusive. As such, methods capable of determining when lapses have occurred may be fruitful research tools, with the potential to save lives if implemented within real-world settings. Here, we capitalised on a recent hierarchical classification method, which uses multivariate decoding to index how well human observers sustain their attention within a dynamic visual environment. We asked whether this method could be used to anticipate behavioural errors based on neural activity measured with electroencephalography (EEG, N = 25). We first decoded how long until a stimulus would reach a task-critical point within a Multiple Object Monitoring (MOM) task from multivariate patterns of EEG amplitudes. The extent to which we could decode this information depended on whether the stimulus was relevant for behaviour, and was lower before participants failed to detect (or ‘missed’) target stimuli relative to hits, presumably due to attentional lapses. We then exploited this drop in neural decodability to predict whether errors were about to occur on each trial. The results form a foundation for sensitive and specific methods to objectively detect errors in sustained attention tasks based on patterns of brain activity.
保持注意力很费力,但对日常生活至关重要。尽管如此,注意力不集中是很常见的,并可能造成致命的后果(例如,在驾驶时)。这些失误的自发性使得研究其潜在现象变得难以捉摸。因此,能够确定何时发生故障的方法可能是富有成效的研究工具,如果在现实环境中实施,可能会挽救生命。在这里,我们利用了最近的分层分类方法,该方法使用多元解码来索引人类观察者在动态视觉环境中保持注意力的程度。我们询问这种方法是否可以用于预测基于脑电图(EEG, N = 25)测量的神经活动的行为错误。我们首先从多目标监测(MOM)任务的多变量脑电图振幅模式中解码了刺激到达任务临界点所需的时间。我们能够解码这些信息的程度取决于刺激是否与行为相关,并且在参与者未能检测(或“错过”)相对于命中目标刺激之前,可能是由于注意力缺失。然后,我们利用神经可解码性的下降来预测每次试验中是否会发生错误。这些结果为基于大脑活动模式客观检测持续注意力任务中的错误的敏感和特定方法奠定了基础。
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引用次数: 0
Comparing developmental neural incongruency effects in reading and arithmetic among children: An ERP study 儿童阅读和算术发育神经不一致效应的比较:一项ERP研究。
IF 3.3 2区 心理学 Q1 BEHAVIORAL SCIENCES Pub Date : 2025-12-11 DOI: 10.1016/j.cortex.2025.12.001
Jie Ma , Brian W.L. Wong , Kelvin F.H. Lui , Jason C.M. Lo , Shuting Huo , Catherine McBride , Urs Maurer
Although reading and arithmetic abilities are considered distinct academic skills, evidence of shared cognitive structures suggests that they may also involve shared brain functions. This study investigated neural incongruency effects between sentence reading and simple addition in primary school children using event-related potentials (ERPs). Sixty children from grades 1, 2 and 3 judged whether the meanings of Chinese sentences and arithmetic additions were correct or not. ERP maps including all electrodes were analysed using timepoint-to-timepoint TANOVA analysis with factors of incongruency, task and age. Behavioural responses were faster in the congruent than incongruent condition, especially for younger children; the age-related reduction in the incongruency effect was more pronounced in the arithmetic than the reading task. TANOVA showed incongruency main effects for the N400 (306–476 msec) that were similar for reading and arithmetic. Importantly, interaction effects of task and incongruency in the early N400 (242–326 msec) time range reflected faster incongruency effects for arithmetic compared to reading. Age did not modulate any of these effects, nor had a significant main effect on ERP. Microstate findings revealed that the N400 effect differed between reading and arithmetic in latency and topographic distribution. Taken together, the results suggest that incorrectness in both reading and arithmetic is reflected by N400 effects that indicate incongruency processing, but this activity differs between reading and arithmetic and starts earlier for arithmetic than reading. Overall, the present study underscores the need for a cross-domain approach to understanding the shared and distinct neurocognitive patterns of academic skills.
虽然阅读和算术能力被认为是不同的学术技能,但共同认知结构的证据表明,它们也可能涉及共同的大脑功能。本研究利用事件相关电位(ERPs)研究小学生句子阅读与简单加法之间的神经不一致效应。60名一、二、三年级的儿童对汉语句子和算术加法的意义进行判断。采用时间点对时间点的TANOVA分析,对包括所有电极在内的ERP图进行分析,并考虑不一致、任务和年龄因素。一致条件下的行为反应比不一致条件下的行为反应快,特别是对于年龄较小的儿童;与年龄相关的不一致效应的降低在算术任务中比在阅读任务中更为明显。TANOVA分析显示N400 (306-476 msec)在阅读和算术方面的主效应不一致。重要的是,在N400早期(242-326 msec)时间范围内,任务和不一致的交互效应反映出算术的不一致效应比阅读更快。年龄没有调节任何这些影响,也没有显著的主要影响ERP。微态结果显示,阅读和算术的N400效应在潜伏期和地形分布上存在差异。综上所述,结果表明,阅读和算术中的不正确性都反映在N400效应中,这表明不一致的处理,但这种活动在阅读和算术之间是不同的,算术比阅读更早开始。总的来说,目前的研究强调需要跨领域的方法来理解学术技能的共享和独特的神经认知模式。
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引用次数: 0
Functional organization of distance-dependent audio-tactile integration is different in rear and front spaces 距离相关的听觉触觉整合功能组织在前后空间存在差异
IF 3.3 2区 心理学 Q1 BEHAVIORAL SCIENCES Pub Date : 2025-12-08 DOI: 10.1016/j.cortex.2025.11.015
Augustin Amiel , Lise Hobeika , Isabelle Viaud-Delmon , Marine Taffou
Peripersonal space mediates animals' interactions with the environment and is thus critical for the implementation of appropriate behaviors. Integrating multisensory information located in peripersonal space induces enhanced behavioral responses and reflects the relevance of external stimuli for the organism's survival. To date, modifications of reaction time related to peripersonal space have mostly been studied using stimuli presented in the frontal space, and limited data are available on other dimensions of peripersonal space. Here, we investigated rear and front defensive peripersonal space by testing whether the distance-dependent behavioral effect of audio-tactile integration varies around the body. Healthy human participants had to detect a tactile stimulation on their hand while an irrelevant sound was approaching them from different parts of space. We used sound spatialization techniques (3D sound) to create sound stimuli looming towards participants' bodies from the front-right, front-left, rear-right, and rear-left quadrants. In the front hemifield, sounds approaching from the left had to be closer to facilitate tactile detection compared to those from the right. In contrast, in the rear hemifield, tactile detection was enhanced at similar distances regardless of whether the sound approached from the left or right. This indicates that human auditory defensive peripersonal space is not homogeneous around the body, showing a lateral asymmetry in the front but not in the rear space. This suggests that perceptual coding of space takes into account action abilities which, in humans, are driven by a front/back organization of the biomechanic skeletal system and of the sensory organs.
周边个人空间调节着动物与环境的互动,因此对适当行为的实施至关重要。整合位于周围个人空间的多感官信息会引起增强的行为反应,并反映出外部刺激与生物体生存的相关性。到目前为止,与反应时间相关的反应时间的改变主要是利用正面空间的刺激来研究的,而在周围空间的其他维度上的数据有限。在此,我们通过测试听觉-触觉整合的距离依赖行为效应是否在身体的各个部位有所不同,来研究前后防御性的个人周围空间。健康的人类参与者必须在一个不相关的声音从空间的不同部分接近他们时,检测到他们手上的触觉刺激。我们使用声音空间化技术(3D声音)来创造声音刺激,从右前、左前、右后和左后象限逼近参与者的身体。在前脑区,与来自右侧的声音相比,来自左侧的声音必须更近,以方便触觉检测。相比之下,在后半脑区,无论声音是从左边还是从右边传来,在相似的距离上,触觉探测都得到了增强。这表明人类听觉防御的周围个人空间在身体周围并不是均匀的,在前部表现出横向不对称,而在后部则没有。这表明,空间的感知编码考虑到了人类的行动能力,而行动能力是由生物力学骨骼系统和感觉器官的前后组织驱动的。
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引用次数: 0
Behavioral constructs and neural correlates of descriptive and responsive speech in post-stroke aphasia 脑卒中后失语症描述性和反应性言语的行为构念和神经相关。
IF 3.3 2区 心理学 Q1 BEHAVIORAL SCIENCES Pub Date : 2025-12-05 DOI: 10.1016/j.cortex.2025.11.012
Mara Barberis , Ella Eycken , Pieter De Clercq , Robin Lemmens , Hugo Van hamme , Maaike Vandermosten
Discourse refers to language that extends beyond a single clause and is used to express ideas, feelings or to interact with others. Persons with post-stroke aphasia often encounter difficulties in discourse, which can severely impede everyday communication. In recent years, discourse has received more attention in both research and clinical practice due to its high ecological validity. However, little is known about the underlying behavioral constructs and neural correlates of discourse in post-stroke aphasia. In the current study, discourse was assessed in 49 persons with chronic aphasia following left-hemispheric (n = 39) or bilateral (n = 10) stroke using picture description from the CAT (descriptive speech) and verbal responses to everyday scenarios from the ANELT (responsive speech). Factor analysis and voxel-wise lesion symptom mapping were performed to investigate the underlying behavioral and neural constructs. Factor analysis revealed four latent constructs that explained 64% of the total variance in the discourse variables: grammatical, phonological, lexical-semantic and macrostructural. Fluency variables were spread across these four different factors. For example, digression was associated with word repetitions and filled pauses, while grammatical deficits were associated with speech rate and long pauses. After correction for multiple comparisons, only the lexical-semantic factor was significantly associated with a left cluster covering lesions in the inferior parietal, superior and middle temporal and lateral occipital regions. In conclusion, this study shows that discourse analysis can reveal both clustered and distributed dimensions and further establishes the role of the left inferior parietal and superior and middle temporal lobe in lexical-semantic abilities.
话语是指超越单个子句,用来表达思想、情感或与他人互动的语言。中风后失语症患者经常遇到言语困难,这可能严重阻碍日常交流。近年来,话语因其较高的生态效度在研究和临床实践中受到越来越多的关注。然而,对于脑卒中后失语症中言语的潜在行为结构和神经相关因素知之甚少。在目前的研究中,对49名左半球(n = 39)或双侧(n = 10)中风后慢性失语症患者的话语进行了评估,使用CAT(描述性言语)的图片描述和ANELT(反应性言语)对日常情景的言语反应。进行因子分析和体素型病变症状映射,以调查潜在的行为和神经结构。因子分析揭示了四个潜在构念,它们解释了话语变量中64%的总变异:语法、语音、词汇语义和宏观结构。流畅性变量分布在这四个不同的因素中。例如,跑题与单词重复和填充停顿有关,而语法缺陷与语速和长停顿有关。经过多次比较校正后,只有词汇-语义因素与覆盖顶叶下、颞上、颞中和枕侧区域病变的左簇显著相关。综上所述,本研究表明语篇分析可以揭示聚类维度和分布维度,并进一步确立了左顶叶下叶和颞中上叶在词汇语义能力中的作用。
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引用次数: 0
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Cortex
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