Cortex最新文献

{"title":"Luria's legacy in the era of cognitive neuroscience","authors":"Marco Catani , Elkhonon Goldberg","doi":"10.1016/j.cortex.2025.02.002","DOIUrl":"10.1016/j.cortex.2025.02.002","url":null,"abstract":"","PeriodicalId":10758,"journal":{"name":"Cortex","volume":"184 ","pages":"Pages 311-313"},"PeriodicalIF":3.2,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143488718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and metabolic profiles in behavioural frontotemporal dementia: Impact of age at onset","authors":"Mattia Losa ,&nbsp;Sara Garbarino ,&nbsp;Alessio Cirone ,&nbsp;Lucia Argenti ,&nbsp;Lorenzo Lombardo ,&nbsp;Francesco Calizzano ,&nbsp;Nicola Girtler ,&nbsp;Andrea Brugnolo ,&nbsp;Pietro Mattioli ,&nbsp;Matteo Bauckneht ,&nbsp;Stefano Raffa ,&nbsp;Gianmario Sambuceti ,&nbsp;Antonio Canosa ,&nbsp;Stefano Caneva ,&nbsp;Michele Piana ,&nbsp;Giulia Bozzo ,&nbsp;Luca Roccatagliata ,&nbsp;Gianluca Serafini ,&nbsp;Antonio Uccelli ,&nbsp;Fabio Gotta ,&nbsp;Matteo Pardini","doi":"10.1016/j.cortex.2025.01.011","DOIUrl":"10.1016/j.cortex.2025.01.011","url":null,"abstract":"<div><h3>Aim</h3><div>Frontotemporal dementia (FTD) is a heterogeneous neurodegenerative disorder, with considerable variability of age-at-onset. We explored clinical and metabolic differences between early- and late-onset behavioural FTD (bvFTD), assuming that they might represent different disease phenotypes.</div></div><div><h3>Materials and methods</h3><div>We retrospectively studied consecutive patients diagnosed with prodromal or overt bvFTD with [¹⁸F]FDG PET scan, neuropsychological assessment (NPS), and Neuropsychiatric Inventory (NPI) available at baseline. Patients were divided into three groups based on age-at-onset: early onset-bvFTD (EO-bvFTD, age&lt;70), late onset-bvFTD (LO-bvFTD, age 70–75) and very late onset-bvFTD (vLO-bvFTD, age&gt;75). NPS and NPI were compared between groups and in the subset of prodromal patients, to study different syndromic phenotypes. Voxel-based analysis compared brain [¹⁸F]FDG PET of EO-bvFTD, LO-bvFTD and vLO-bvFTD independently, with respect to healthy controls, to explore metabolic differences. An inter-regional metabolic covariance analysis was performed in frontal lobe subregions, to explore differences in brain connectivity. Moreover, we supported our result using a correlation-based approach on clinical and metabolic variables.</div></div><div><h3>Results</h3><div>101 bvFTD (62 prodromal bvFTD) were enrolled (EO-bvFTD: <em>n</em> = 36, prodromal <em>n</em> = 21; LO-bvFTD: <em>n</em> = 36, prodromal: <em>n</em> = 22; vLO-bvFTD: <em>n</em> = 29, prodromal: <em>n</em> = 19). Greater verbal memory deficit was evident in LO-bvFTD and vLO-bvFTD compared to EO-bvFTD (immediate recall: <em>p</em> = .018; <em>p</em> = .024; delayed recall: both <em>p</em> = .001, respectively), with similar results in the subset of prodromal patients. EO-bvFTD and LO-bvFTD had a higher behavioural severity than vLO-bvFTD. LO-bvFTD and vLO-bvFTD showed more widespread relative hypometabolism, with a greater involvement of posterior, subcortical and temporo-limbic regions compared with EO-bvFTD. Moreover, vLO-bvFTD showed a different pattern of intrafrontal metabolic covariance compared to EO-bvFTD and LO-bvFTD.</div></div><div><h3>Discussion</h3><div>The cognitive–behavioural profile of bvFTD differs between early- and late-onset, already from the prodromal stage of the disease. Both metabolic pattern and functional connectivity vary based on age-at-onset. Understanding these differences could contribute to improve diagnostic accuracy and understanding the underling pathological heterogeneity.</div></div>","PeriodicalId":10758,"journal":{"name":"Cortex","volume":"185 ","pages":"Pages 84-95"},"PeriodicalIF":3.2,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143474144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Individual differences in anterograde memory for details relate to posterior hippocampal volume","authors":"Jeremy Gardette ,&nbsp;Gabriel Besson ,&nbsp;Marion Baillet ,&nbsp;Lou Rizzolo ,&nbsp;Justinas Narbutas ,&nbsp;Maxime Van Egroo ,&nbsp;Daphne Chylinski ,&nbsp;Pierre Maquet ,&nbsp;Eric Salmon ,&nbsp;Gilles Vandewalle ,&nbsp;Fabienne Collette ,&nbsp;Christine Bastin","doi":"10.1016/j.cortex.2025.01.012","DOIUrl":"10.1016/j.cortex.2025.01.012","url":null,"abstract":"<div><div>In recent years, there has been a growing interest in individual differences in autobiographical memory. The ability to recall details from personal past events correlates with the volume of specific hippocampal subfields in healthy adults. Although the posterior hippocampus is believed to process detailed memory representations independently of the memory's age, little is known about individual differences in the ability to recall newly encoded events in detail, and how these differences relate to hippocampal subregions. In this preregistered study, we scored the story recalls from 89 healthy middle-aged participants with a newly designed method that allows to distinguish information recalled in detail from gist recall (i.e., when only the general idea is recalled). After a 20-min delay, detailed information was transformed into gists, which is in line with recent evidence that gists can emerge rapidly after a new experience. In addition, we segmented the anterior and posterior hippocampal subfields CA1, CA2/3, dentate gyrus, and subiculum from high-resolution structural MRI. As predicted, the volume of the posterior hippocampus was positively correlated with the detail score but not with the gist score, yet this effect was significant in the right hemisphere only. We also observed trends towards associations between the detail score and specific subfields of the right posterior hippocampus, but none survived statistical correction for multiple comparisons. Finally, we found no evidence for the expected age-related increase in the use of gists over details. Taken together, these results suggest that the posterior hippocampus supports detail memory in the recall of both remote and newly acquired memories.</div></div>","PeriodicalId":10758,"journal":{"name":"Cortex","volume":"185 ","pages":"Pages 64-73"},"PeriodicalIF":3.2,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143453058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognitive reserve types and depressive symptoms development in late-life: A population-based cohort study","authors":"Federico Triolo ,&nbsp;Giulia Grande ,&nbsp;Ingrid Ekström ,&nbsp;Erika J. Laukka ,&nbsp;Stefan Fors ,&nbsp;Anna Marseglia ,&nbsp;Serhiy Dekhtyar","doi":"10.1016/j.cortex.2025.02.001","DOIUrl":"10.1016/j.cortex.2025.02.001","url":null,"abstract":"<div><h3>Introduction</h3><div>Cognitive reserve (CR) describes individual differences in susceptibility to brain damage that translates into varying dementia onsets and may also influence the occurrence of depressive symptoms. Within a population-based cohort of older people, we investigated two operationalizations of CR, residual- and activity-based approaches, in their association with the development of depressive symptoms.</div></div><div><h3>Methods</h3><div>We analyzed longitudinal data on 402 dementia- and depression-free adults aged 60+ from the Swedish National Study on Aging and Care in Kungsholmen (SNAC-K) who underwent brain MRI at baseline. Residual-based reserve was derived by regressing episodic memory on a brain-integrity index incorporating six structural MRI markers. Activity-based reserve factored lifelong CR-enhancing experiences, including education, work complexity, social network, and leisure activities. Clinically relevant depressive symptoms were defined as a Montgomery–Åsberg Depression Rating Scale score &gt;6. Cox hazard models were used to explore the association between both residual- and activity-based CR measures (categorized in tertiles) and incidence of depressive symptoms over a 15-year follow-up, while accounting for sociodemographic, clinical, behavioral factors, and brain integrity. Analyses for the activity-based measure were replicated in the full SNAC-K sample (<em>N</em> = 2709), further exploring depression diagnosis as additional outcome.</div></div><div><h3>Results</h3><div>Compared to low levels, higher levels of residual-based CR were associated with a lower hazard of depressive symptom onset in fully adjusted models (HR: .43, 95%CI .22, .84). While activity-based CR was not significantly associated with developing depressive symptoms in the MRI subsample (HR_high .47, 95%CI .21, 1.04), it was in the full sample (HR_high .52, 95%CI .39, .71). Activity-based CR was further associated with depression diagnoses in the full sample (HR_high: .45, 95%CI .31, .65).</div></div><div><h3>Discussion</h3><div>Largely independent of its measurement, CR appears to influence depressive symptomatology in late life. Reserve-enhancing initiatives may be beneficial not only for cognitive but also for mental health in older people.</div></div>","PeriodicalId":10758,"journal":{"name":"Cortex","volume":"185 ","pages":"Pages 74-83"},"PeriodicalIF":3.2,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143463643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outbalanced: The cross-cortical effects of prefrontal neuromodulation in posterior parietal cortex","authors":"Maryam Farshad ,&nbsp;Beatrix Barth ,&nbsp;Jennifer Svaldi ,&nbsp;Christina Artemenko ,&nbsp;Philipp A. Schroeder","doi":"10.1016/j.cortex.2025.01.009","DOIUrl":"10.1016/j.cortex.2025.01.009","url":null,"abstract":"<div><div>Cognitive phenomena such as the Spatial–Numerical Association of Response Codes (SNARC) effect can arise in the fronto-parietal cortical network. Prior neuromodulation studies with cathodal transcranial direct current stimulation (tDCS) over the left prefrontal cortex (PFC) reduced the SNARC effect. Prior neuroimaging studies with functional near-infrared spectroscopy (fNIRS), however, showed signatures of the SNARC effect in the posterior parietal cortex (PPC). In this study, we investigated the distant neural effect of prefrontal neuromodulation on hemodynamic activity in the parietal cortex by combining cathodal tDCS with fNIRS. The SNARC effect and the numerical distance effect (NDE) were assessed in an event-related cross-over design (<em>N</em> = 45), when cathodal tDCS of 1 mA at the left PFC was applied simultaneously during the measurement of fNIRS covering the bilateral PPC. At the behavioral level, prefrontal tDCS did not significantly reduce the SNARC effect, indicating that the replication failed here. Crucially, at the neuronal level, prefrontal tDCS reduced left parietal activation associated with the SNARC effect but not with the NDE. This neuronal effect of tDCS in a remote site was shown in preregistered primary region-of-interest analyses and in secondary all-channel analyses. The results showed how the combination of neuromodulation and neuroimaging shed light on the fronto-parietal network responsible for numerical cognition, and how fNIRS can assess the distant neural effects of cathodal tDCS.</div></div>","PeriodicalId":10758,"journal":{"name":"Cortex","volume":"185 ","pages":"Pages 96-112"},"PeriodicalIF":3.2,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143508123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aleksander Luria and Oliver Sacks: An inspiring correspondence","authors":"Sergio Della Sala ,&nbsp;Kate Edgar ,&nbsp;Elkhonon Goldberg ,&nbsp;Marco Catani","doi":"10.1016/j.cortex.2025.01.010","DOIUrl":"10.1016/j.cortex.2025.01.010","url":null,"abstract":"<div><div>Aleksander Luria and Oliver Sacks corresponded from 1973 to Luria’s death in 1977. Here we reproduce and analyse the initial two years of their exchange, exploring their shared views on key themes including \"Romantic Science,\" the value of individual patient narratives, and the socio-historical context on brain development . The correspondence reveals Luria's mentorship of Sacks and his significant impact on Sacks' approach to neurological case studies.</div></div>","PeriodicalId":10758,"journal":{"name":"Cortex","volume":"184 ","pages":"Pages 298-310"},"PeriodicalIF":3.2,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143387287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The network neuropsychology of juvenile myoclonic epilepsy","authors":"Camille Garcia-Ramos ,&nbsp;Aaron F. Struck ,&nbsp;Veena A. Nair ,&nbsp;Vivek Prabhakaran ,&nbsp;Theodore P. Imhoff-Smith ,&nbsp;Nagesh Adluru ,&nbsp;Dace N. Almane ,&nbsp;Jana E. Jones ,&nbsp;Bruce P. Hermann","doi":"10.1016/j.cortex.2024.12.025","DOIUrl":"10.1016/j.cortex.2024.12.025","url":null,"abstract":"<div><div>Unknown in the clinical neuropsychology of Juvenile Myoclonic Epilepsy (JME) is the impact of the disorder on the nature of the relationships of specific cognitive abilities among themselves including their patterns of integration, segregation, and topographical organization—that is, the network neuropsychology of JME remains to be addressed. Examined here is the status of cognitive networks in JME and whether similar network alterations are present in the unaffected siblings of patients with this genetic generalized epilepsy. Participants included 78 with JME (mean age = 19.8 <span><math><mrow><mo>±</mo></mrow></math></span> 3.7 yrs), 19 unaffected siblings (mean age = 15.9 <span><math><mrow><mo>±</mo></mrow></math></span> 3.3 yrs) and 43 unrelated controls (mean age = 20.2 <span><math><mrow><mo>±</mo></mrow></math></span> 3.2 yrs), all administered a comprehensive clinical neuropsychological battery from which 15 metrics served as nodes for graph theory analyses. Calculated were global metric indices (i.e., normalized global efficiency, normalized average clustering coefficient, modularity) and landmark “hubs” by calculating betweenness centrality. Salient JME network findings included: 1) significantly greater intercorrelation of test measures (i.e., increased positive manifold), 2) significantly lower segregation (i.e., normalized average clustering coefficient) but similar network efficiency (i.e., normalized global efficiency), and 3) significantly lower strength of the division of the cognitive modules in the network (i.e., modularity index). Regarding the topographical structure of identified cognitive networks (i.e., their community structure), unaffected siblings and unrelated controls demonstrated three cognitive modules (speed/executive function, perceptual, language) while JME demonstrated two modules—one of which was undifferentiated and “g-like”, and speed/executive function. Overall, JME is associated with less segregation of cognitive subsystems (i.e., modules) indicating less specialization in cognitive processes, abnormalities in the interrelationships of psychometric measures as well as the general configuration of their resulting cognitive networks (fewer in number and atypical in content and structure) which appear to be contributing to their generally poorer cognitive status compared to controls. Unaffected siblings show some penetrance of these atypical network features.</div></div>","PeriodicalId":10758,"journal":{"name":"Cortex","volume":"185 ","pages":"Pages 20-30"},"PeriodicalIF":3.2,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143395748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prospective memory and quality of life in older and younger autistic adults","authors":"Amanda Roestorf ,&nbsp;Dermot M. Bowler ,&nbsp;Sebastian B. Gaigg ,&nbsp;Patricia Howlin","doi":"10.1016/j.cortex.2025.01.006","DOIUrl":"10.1016/j.cortex.2025.01.006","url":null,"abstract":"<div><div>Ageing in late adulthood is generally accompanied by diminished prospective memory (PM), which itself is associated with declining quality of life (QoL). Given that autistic individuals are often reported as having PM difficulties and diminished QoL, we aimed to establish whether these measures are also associated in these individuals as they grow older. We administered questionnaire measures of prospective and retrospective memory (PM and RM) and of overall and health-related quality of life (QoL) and experimental measures of time-based and event-based PM (TBPM and EBPM) to 35 autistic and 22 non-autistic adults aged from 23 to 80 years. The autistic participants reported higher levels of PM and RM difficulties than non-autistic participants but that these reports did not correlate with age nor with the experimental TBPM or EBPM measures in either group. Age correlated negatively with two of the experimental measures of TBPM for the non-autistic participants, replicating earlier studies. Autistic participants showed diminished performance on the TBPM but not the EBPM measures, replicating the majority of earlier PM studies in autism. Autistic participants also reported lower overall and health-related QoL, but there were no age-related differences for either measure in either diagnostic group. Self-reported PM and RM correlated significantly with health-related QoL in both the autistic and non-autistic participants. Overall QoL was positively associated with TBPM accuracy in the non-autistic participants. In addition to confirming earlier findings showing that autistic individuals have greater difficulties with TBPM compared to EBPM, our findings suggest that neither EBPM nor TBPM difficulties appear to adversely affect their overall or health-related QoL. The patterning of the autistic participants’ results also suggests that the mechanisms underlying their performance on the tasks used in this study may differ from those of the non-autistic participants, pointing to the need for careful task analysis when designing future investigations.</div></div>","PeriodicalId":10758,"journal":{"name":"Cortex","volume":"185 ","pages":"Pages 31-49"},"PeriodicalIF":3.2,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143395749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A taxometric analysis of developmental prosopagnosia: Evidence for a categorically distinct impairment","authors":"Sarah Bate ,&nbsp;Emma Portch ,&nbsp;Rachel J. Bennetts ,&nbsp;Benjamin A. Parris","doi":"10.1016/j.cortex.2024.10.021","DOIUrl":"10.1016/j.cortex.2024.10.021","url":null,"abstract":"<div><div>Poor performance on cognitive assessment tasks may indicate a selective ‘impairment’. However, it is unclear whether such difficulties separate the individual from the general population qualitatively (i.e., they form a discrete group) or quantitatively (i.e., they represent the lower end of a continuous distribution). Taxometric methods address this question but have rarely been applied to cognitive disorders. This study examined the latent structure of developmental prosopagnosia (DP) – a relatively selective deficit in face recognition that occurs in the absence of neurological injury. Multiple taxometric procedures were applied to dominant diagnostic indices of face recognition ability across two independent datasets. All analyses supported a categorical outcome, even for mild cases of DP, suggesting that it is a qualitatively distinct condition. This finding has significant implications for our understanding of DP given it has traditionally been viewed as a continuous impairment. In particular, existing (arbitrary) diagnostic cut-offs may be too conservative, underestimating prevalence rates and prohibiting big-data approaches to theoretical study. More broadly, these conclusions support application of the taxometric method to many other cognitive processes where weaknesses are predominantly assumed to reside on a continuous distribution.</div></div>","PeriodicalId":10758,"journal":{"name":"Cortex","volume":"183 ","pages":"Pages 131-145"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142784369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Structure–function relationships in the human aging brain: An account of cross-sectional and longitudinal multimodal neuroimaging studies","authors":"Grégoria Kalpouzos ,&nbsp;Jonas Persson","doi":"10.1016/j.cortex.2024.12.004","DOIUrl":"10.1016/j.cortex.2024.12.004","url":null,"abstract":"<div><div>The patterns of brain activation and functional connectivity, task-related and task-free, as a function of age have been well documented over the past 30 years. However, the aging brain undergoes structural changes that are likely to affect the functional properties of the brain. The relationship between brain structure and function started to be investigated more recently. Brain structure and brain function can influence behavioral outcomes independently, and several studies highlight independent contribution of structure and function on cognition. Here, a central assumption is that brain structure also affects behavior indirectly through its influence on brain function. In such a model, structure supports function. Although findings generally suggest that structure may indeed influence function, the direction of the associations, the variability in terms of regional effects and age windows when associations are observed vary greatly. Also, a certain number of studies highlight the independent contribution of structure and function on cognition. A critical aspect of studying aging is the necessity of longitudinal designs, allowing to observe true aging effects – as compared with age differences in cross-sectional designs. This review aims to give an updated account on research dealing with multimodal neuroimaging in aging, and more specifically on the links between structure and function and associated cognitive outcomes, putting in parallel findings from cross-sectional and longitudinal studies. Additionally, we discuss potential mechanisms by which age-related changes in structure may affect function, but also factors (sample characteristics, methodology) that may contribute to the heterogeneity of the findings and the lack of consensus on the associations between structure, function, cognition and aging.</div></div>","PeriodicalId":10758,"journal":{"name":"Cortex","volume":"183 ","pages":"Pages 274-289"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142930759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}