首页 > 最新文献

Cortex最新文献

英文 中文
Cover figure 封面人物
IF 3.2 2区 心理学 Q1 BEHAVIORAL SCIENCES Pub Date : 2024-11-01 DOI: 10.1016/S0010-9452(24)00277-6
{"title":"Cover figure","authors":"","doi":"10.1016/S0010-9452(24)00277-6","DOIUrl":"10.1016/S0010-9452(24)00277-6","url":null,"abstract":"","PeriodicalId":10758,"journal":{"name":"Cortex","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142573015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reduced resting-state periodic beta power in adults who stutter is related to sensorimotor control of speech execution 口吃成人的静息态周期性β功率降低与言语执行的感觉运动控制有关
IF 3.2 2区 心理学 Q1 BEHAVIORAL SCIENCES Pub Date : 2024-10-24 DOI: 10.1016/j.cortex.2024.09.016

Objective

The primary aim of the current study was to determine whether adults who stutter (AWS) present with anomalous periodic beta (β) rhythms when compared to typically fluent adults in the eyes-open resting state. A second aim was to determine whether lower β power in the RS is related to a measure of β event-related desynchronization (ERD) during syllable sequence execution.

Methods

EEG data was collected from 128 channels in a 5 min, eyes-open resting state condition and from a syllable sequence repetition task. Temporal independent component analysis (ICA) was used to separate volume conducted EEG sources and to find a set of component weights common to the RS and syllable repetition task. Both traditional measures of power spectral density (PSD) and parameterized spectra were computed for components showing peaks in the β band (13–30 Hz). Parameterization was used to evaluate separable components adjusted for the 1/f part of the spectrum.

Results

ICA revealed frontal-parietal midline and lateral sensorimotor (μ) components common to the RS and a syllable repetition task with peaks in the β band. The entire spectrum for each component was modeled using the FOOOF algorithm. Independent samples t-tests revealed significantly lower periodic β in midline central-parietal and lateral sensorimotor components in AWS. Regression analysis suggested a significant relationship between left periodic sensorimotor β power in the RS and ERD during syllable sequence execution.

Conclusions

Findings suggest that periodic β peaks in the spectrum are related to hypothesized underlying pathophysiological differences in stuttering, including midline rhythms associated the default mode network (DMN) and lateral sensorimotor rhythms associated with the control of movement.
目的本研究的主要目的是确定口吃成人(AWS)在睁眼休息状态下与典型流利成人相比是否存在异常的周期性β(β)节奏。第二个目的是确定在音节序列执行过程中,RS中较低的β功率是否与β事件相关不同步(ERD)的测量有关。方法在5分钟睁眼休息状态和音节序列重复任务中,从128个通道收集EEG数据。采用时间独立分量分析(ICA)来分离进行脑电图的音量源,并找到一组在静息状态和音节重复任务中通用的分量权重。对于在 β 频段(13-30 Hz)显示峰值的成分,计算了传统的功率谱密度 (PSD) 和参数化频谱。结果显示,额叶-顶叶中线和外侧感觉运动(μ)成分与 RS 和音节重复任务相同,在 β 频段有峰值。使用 FOOOF 算法对每个成分的整个频谱进行建模。独立样本 t 检验显示,AWS 中线中央顶叶和外侧感觉运动成分的周期性 β 明显较低。回归分析表明,在音节序列执行过程中,RS 和 ERD 中的左侧周期性感觉运动 β 功率之间存在显著关系。结论研究结果表明,频谱中的周期性 β 峰值与假设的口吃潜在病理生理差异有关,包括与默认模式网络 (DMN) 相关的中线节律和与运动控制相关的外侧感觉运动节律。
{"title":"Reduced resting-state periodic beta power in adults who stutter is related to sensorimotor control of speech execution","authors":"","doi":"10.1016/j.cortex.2024.09.016","DOIUrl":"10.1016/j.cortex.2024.09.016","url":null,"abstract":"<div><h3>Objective</h3><div>The primary aim of the current study was to determine whether adults who stutter (AWS) present with anomalous periodic beta (β) rhythms when compared to typically fluent adults in the eyes-open resting state. A second aim was to determine whether lower β power in the RS is related to a measure of β event-related desynchronization (ERD) during syllable sequence execution.</div></div><div><h3>Methods</h3><div>EEG data was collected from 128 channels in a 5 min, eyes-open resting state condition and from a syllable sequence repetition task. Temporal independent component analysis (ICA) was used to separate volume conducted EEG sources and to find a set of component weights common to the RS and syllable repetition task. Both traditional measures of power spectral density (PSD) and parameterized spectra were computed for components showing peaks in the β band (13–30 Hz). Parameterization was used to evaluate separable components adjusted for the 1/f part of the spectrum.</div></div><div><h3>Results</h3><div>ICA revealed frontal-parietal midline and lateral sensorimotor (μ) components common to the RS and a syllable repetition task with peaks in the β band. The entire spectrum for each component was modeled using the FOOOF algorithm. Independent samples <em>t</em>-tests revealed significantly lower periodic β in midline central-parietal and lateral sensorimotor components in AWS. Regression analysis suggested a significant relationship between left periodic sensorimotor β power in the RS and ERD during syllable sequence execution.</div></div><div><h3>Conclusions</h3><div>Findings suggest that periodic β peaks in the spectrum are related to hypothesized underlying pathophysiological differences in stuttering, including midline rhythms associated the default mode network (DMN) and lateral sensorimotor rhythms associated with the control of movement.</div></div>","PeriodicalId":10758,"journal":{"name":"Cortex","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142593168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Structural and functional correlates of olfactory reward processing in behavioral variant frontotemporal dementia 行为变异型额颞叶痴呆症患者嗅觉奖赏处理的结构和功能相关性。
IF 3.2 2区 心理学 Q1 BEHAVIORAL SCIENCES Pub Date : 2024-10-22 DOI: 10.1016/j.cortex.2024.09.011
The behavioral variant of frontotemporal dementia (bvFTD) includes symptoms that reflect altered pursuit of rewards, including food, alcohol, and money. Little is known, however, about how these reward changes relate to atrophy and functional connectivity within reward-related regions. The goal of this study was to examine the structural and functional correlates of valence perception for olfactory rewards in 24 patients with bvFTD. Regression analysis of resting-state brain functional connectivity indicated that more positive valence ratings of olfactory stimuli were predicted by ventral pallidum connectivity to other reward circuit regions, particularly functional connectivity between ventral pallidum and bilateral anterior cingulate cortex/ventromedial prefrontal cortex. Structural analysis showed that atrophy of the anterior cingulate cortex was also significantly associated with perceiving stimuli as more rewarding. Finally, there was a significant interaction between ventral pallidum connectivity and atrophy of the anterior cingulate cortex. More specifically, the ventral pallidum connectivity had a greater effect on the positive perception of olfactory stimuli in the setting of low anterior cingulate cortex volume. These findings indicate that atrophy and functional connectivity within reward-relevant regions exert independent and interacting effects on the perception of pleasantness in bvFTD, potentially due to changes in hedonic “liking” signals.
额颞叶痴呆的行为变异型(bvFTD)的症状包括对食物、酒精和金钱等奖赏的追求发生改变。然而,人们对这些奖赏变化与奖赏相关区域的萎缩和功能连接之间的关系知之甚少。本研究的目的是检测 24 名 bvFTD 患者对嗅觉奖赏的价值感知的结构和功能相关性。对静息态大脑功能连接的回归分析表明,腹侧苍白球与其他奖赏回路区域的连接,尤其是腹侧苍白球与双侧前扣带皮层/内侧前额叶皮层之间的功能连接,可以预测患者对嗅觉刺激的积极价值评价。结构分析表明,前扣带皮层的萎缩也与认为刺激更有奖赏显著相关。最后,腹侧苍白球连通性与前扣带皮层萎缩之间存在明显的交互作用。更具体地说,在前扣带皮层容量较低的情况下,腹侧苍白球连接对嗅觉刺激的积极感知有更大的影响。这些研究结果表明,奖赏相关区域的萎缩和功能连通性对bvFTD患者的愉快感产生了独立和相互作用的影响,这可能是由于享乐性 "喜欢 "信号的变化所致。
{"title":"Structural and functional correlates of olfactory reward processing in behavioral variant frontotemporal dementia","authors":"","doi":"10.1016/j.cortex.2024.09.011","DOIUrl":"10.1016/j.cortex.2024.09.011","url":null,"abstract":"<div><div>The behavioral variant of frontotemporal dementia (bvFTD) includes symptoms that reflect altered pursuit of rewards, including food, alcohol, and money. Little is known, however, about how these reward changes relate to atrophy and functional connectivity within reward-related regions. The goal of this study was to examine the structural and functional correlates of valence perception for olfactory rewards in 24 patients with bvFTD. Regression analysis of resting-state brain functional connectivity indicated that more positive valence ratings of olfactory stimuli were predicted by ventral pallidum connectivity to other reward circuit regions, particularly functional connectivity between ventral pallidum and bilateral anterior cingulate cortex/ventromedial prefrontal cortex. Structural analysis showed that atrophy of the anterior cingulate cortex was also significantly associated with perceiving stimuli as more rewarding. Finally, there was a significant interaction between ventral pallidum connectivity and atrophy of the anterior cingulate cortex. More specifically, the ventral pallidum connectivity had a greater effect on the positive perception of olfactory stimuli in the setting of low anterior cingulate cortex volume. These findings indicate that atrophy and functional connectivity within reward-relevant regions exert independent and interacting effects on the perception of pleasantness in bvFTD, potentially due to changes in hedonic “liking” signals.</div></div>","PeriodicalId":10758,"journal":{"name":"Cortex","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142564132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cotard's syndrome before Cotard: A commentary on : Delusions in postpartum psychosis: Implications for cognitive theories. 科塔德之前的科塔德综合征:对......的评论产后精神病的妄想:对认知理论的影响。
IF 3.2 2区 心理学 Q1 BEHAVIORAL SCIENCES Pub Date : 2024-10-22 DOI: 10.1016/j.cortex.2024.09.010
Brian A Sharpless, Jan Dirk Blom
{"title":"Cotard's syndrome before Cotard: A commentary on : Delusions in postpartum psychosis: Implications for cognitive theories.","authors":"Brian A Sharpless, Jan Dirk Blom","doi":"10.1016/j.cortex.2024.09.010","DOIUrl":"https://doi.org/10.1016/j.cortex.2024.09.010","url":null,"abstract":"","PeriodicalId":10758,"journal":{"name":"Cortex","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142564131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unveiling spatial and non-spatial aspects of neglect in everyday behavior. 揭示日常行为中忽视的空间和非空间方面。
IF 3.2 2区 心理学 Q1 BEHAVIORAL SCIENCES Pub Date : 2024-10-22 DOI: 10.1016/j.cortex.2024.10.002
Brigitte C Kaufmann, Paolo Bartolomeo, Monica N Toba
{"title":"Unveiling spatial and non-spatial aspects of neglect in everyday behavior.","authors":"Brigitte C Kaufmann, Paolo Bartolomeo, Monica N Toba","doi":"10.1016/j.cortex.2024.10.002","DOIUrl":"https://doi.org/10.1016/j.cortex.2024.10.002","url":null,"abstract":"","PeriodicalId":10758,"journal":{"name":"Cortex","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142557344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Working memory related brain-behavior associations in the context of socioeconomic and psychosocial deprivation 社会经济和社会心理剥夺背景下与大脑工作记忆相关的行为关联。
IF 3.2 2区 心理学 Q1 BEHAVIORAL SCIENCES Pub Date : 2024-10-22 DOI: 10.1016/j.cortex.2024.09.013
Burgeoning neuroimaging research documents the associations between working memory (WM)-associated neural and behavioral responses. However, these associations have yielded small and inconsistent effect sizes. We hypothesize that one reason for the weakened brain-behavior associations stems from different environmental contexts. Specifically, little research has examined how exposure to adverse rearing environments accounts for variability in brain-behavior relations. Deprivation, characterized by an absence of cognitive and positive social stimulation, has been shown to compromise children's neurocognitive development. Hence, informed by an ecological approach to developmental neuroscience, the present study aims to investigate if psychosocial and socioeconomic deprivation serves as moderators in the associations between neural responses and behaviors during a WM task. Using data from the Adolescent Brain Cognitive Development study (N = 11, 878, Mage = 9.48, 47.8% female, 52.0% White), we found that psychosocial, but not socioeconomic deprivation, significantly attenuated the positive association between WM-related neural activation within the frontoparietal network and attendant behavioral performance. Specifically, children exposed to higher levels of psychosocial deprivation exhibited weaker brain-behavior relations during a WM task. This finding suggests that a certain level of neural response during cognitive tasks may correspond to different levels of behavioral performance depending on children's rearing environment, highlighting the importance of contextual factors in understanding the brain and cognitive development.
不断涌现的神经成像研究记录了工作记忆(WM)相关神经和行为反应之间的联系。然而,这些关联产生的效应大小很小,而且不一致。我们假设,大脑与行为之间关联减弱的一个原因是环境背景不同。具体来说,很少有研究探讨不良的饲养环境如何导致大脑与行为关系的变化。事实证明,以缺乏认知和积极的社会刺激为特征的匮乏会损害儿童的神经认知发展。因此,本研究以发育神经科学的生态学方法为基础,旨在研究社会心理和社会经济剥夺是否会调节WM任务中神经反应和行为之间的关联。利用青少年大脑认知发展研究(N = 11, 878, Mage = 9.48, 47.8% 为女性,52.0% 为白人)的数据,我们发现,社会心理而非社会经济剥夺显著削弱了前顶叶网络中与 WM 相关的神经激活与相应行为表现之间的正相关。具体来说,社会心理剥夺程度较高的儿童在进行 WM 任务时,大脑与行为之间的关系较弱。这一发现表明,认知任务中一定程度的神经反应可能对应于不同程度的行为表现,这取决于儿童的养育环境,凸显了环境因素对理解大脑和认知发展的重要性。
{"title":"Working memory related brain-behavior associations in the context of socioeconomic and psychosocial deprivation","authors":"","doi":"10.1016/j.cortex.2024.09.013","DOIUrl":"10.1016/j.cortex.2024.09.013","url":null,"abstract":"<div><div>Burgeoning neuroimaging research documents the associations between working memory (WM)-associated neural and behavioral responses. However, these associations have yielded small and inconsistent effect sizes. We hypothesize that one reason for the weakened brain-behavior associations stems from different environmental contexts. Specifically, little research has examined how exposure to adverse rearing environments accounts for variability in brain-behavior relations. Deprivation, characterized by an absence of cognitive and positive social stimulation, has been shown to compromise children's neurocognitive development. Hence, informed by an ecological approach to developmental neuroscience, the present study aims to investigate if psychosocial and socioeconomic deprivation serves as moderators in the associations between neural responses and behaviors during a WM task. Using data from the Adolescent Brain Cognitive Development study (N = 11, 878, M<sub>age</sub> = 9.48, 47.8% female, 52.0% White), we found that psychosocial, but not socioeconomic deprivation, significantly attenuated the positive association between WM-related neural activation within the frontoparietal network and attendant behavioral performance. Specifically, children exposed to higher levels of psychosocial deprivation exhibited weaker brain-behavior relations during a WM task. This finding suggests that a certain level of neural response during cognitive tasks may correspond to different levels of behavioral performance depending on children's rearing environment, highlighting the importance of contextual factors in understanding the brain and cognitive development.</div></div>","PeriodicalId":10758,"journal":{"name":"Cortex","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142564134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reduced on-line speech gesture integration during multimodal language processing in adults with moderate-severe traumatic brain injury: Evidence from eye-tracking 中重度脑外伤成人在多模态语言处理过程中的在线语音手势整合能力降低:来自眼动追踪的证据。
IF 3.2 2区 心理学 Q1 BEHAVIORAL SCIENCES Pub Date : 2024-10-22 DOI: 10.1016/j.cortex.2024.08.008

Background

Language is multimodal and situated in rich visual contexts. Language is also incremental, unfolding moment-to-moment in real time, yet few studies have examined how spoken language interacts with gesture and visual context during multimodal language processing. Gesture is a rich communication cue that is integrally related to speech and often depicts concrete referents from the visual world. Using eye-tracking in an adapted visual world paradigm, we examined how participants with and without moderate-severe traumatic brain injury (TBI) use gesture to resolve temporary referential ambiguity.

Methods

Participants viewed a screen with four objects and one video. The speaker in the video produced sentences (e.g., “The girl will eat the very good sandwich”), paired with either a meaningful gesture (e.g., sandwich-holding gesture) or a meaningless grooming movement (e.g., arm scratch) at the verb “will eat.” We measured participants’ gaze to the target object (e.g., sandwich), a semantic competitor (e.g., apple), and two unrelated distractors (e.g., piano, guitar) during the critical window between movement onset in the gesture modality and onset of the spoken referent in speech.

Results

Both participants with and without TBI were more likely to fixate the target when the speaker produced a gesture compared to a grooming movement; however, relative to non-injured participants, the effect was significantly attenuated in the TBI group.

Discussion

We demonstrated evidence of reduced speech-gesture integration in participants with TBI relative to non-injured peers. This study advances our understanding of the communicative abilities of adults with TBI and could lead to a more mechanistic account of the communication difficulties adults with TBI experience in rich communication contexts that require the processing and integration of multiple co-occurring cues. This work has the potential to increase the ecological validity of language assessment and provide insights into the cognitive and neural mechanisms that support multimodal language processing.
背景介绍语言是多模态的,处于丰富的视觉语境中。语言也是渐进的,每时每刻都在实时展开,但很少有研究探讨在多模态语言处理过程中,口语是如何与手势和视觉语境相互作用的。手势是一种丰富的交流线索,它与语音紧密相关,通常描绘的是视觉世界中的具体参照物。我们在一个经过调整的视觉世界范例中使用眼动跟踪技术,研究了患有和未患有中度严重创伤性脑损伤(TBI)的参与者如何使用手势来解决暂时性的指代模糊问题:方法:参与者观看屏幕上的四个物体和一段视频。视频中的说话者会说出一些句子(例如 "这个女孩会吃掉这个非常好吃的三明治"),并在动词 "会吃掉 "处配以一个有意义的手势(例如握住三明治的手势)或一个无意义的修饰动作(例如抓手臂)。我们测量了参与者在手势模式中的动作开始与语音模式中的口语指代物开始之间的关键窗口期对目标物(如三明治)、语义竞争者(如苹果)和两个不相关的干扰物(如钢琴、吉他)的注视情况:与梳理动作相比,当说话者做出手势时,患有和未患有创伤性脑损伤的参与者都更有可能固定目标;然而,与未受伤的参与者相比,创伤性脑损伤组的效果显著减弱:讨论:我们证明了创伤性脑损伤参与者的语言-手势整合能力相对于未受伤的同龄人有所降低。这项研究加深了我们对患有创伤性脑损伤的成年人的交流能力的理解,并能从机制上解释患有创伤性脑损伤的成年人在需要处理和整合多种共存线索的丰富交流环境中遇到的交流困难。这项工作有可能提高语言评估的生态有效性,并让我们深入了解支持多模态语言处理的认知和神经机制。
{"title":"Reduced on-line speech gesture integration during multimodal language processing in adults with moderate-severe traumatic brain injury: Evidence from eye-tracking","authors":"","doi":"10.1016/j.cortex.2024.08.008","DOIUrl":"10.1016/j.cortex.2024.08.008","url":null,"abstract":"<div><h3>Background</h3><div>Language is multimodal and situated in rich visual contexts. Language is also incremental, unfolding moment-to-moment in real time, yet few studies have examined how spoken language interacts with gesture and visual context during multimodal language processing. Gesture is a rich communication cue that is integrally related to speech and often depicts concrete referents from the visual world. Using eye-tracking in an adapted visual world paradigm, we examined how participants with and without moderate-severe traumatic brain injury (TBI) use gesture to resolve temporary referential ambiguity.</div></div><div><h3>Methods</h3><div>Participants viewed a screen with four objects and one video. The speaker in the video produced sentences (e.g., “The girl will eat the very good sandwich”), paired with either a meaningful gesture (e.g., sandwich-holding gesture) or a meaningless grooming movement (e.g., arm scratch) at the verb “will eat.” We measured participants’ gaze to the target object (e.g., sandwich), a semantic competitor (e.g., apple), and two unrelated distractors (e.g., piano, guitar) during the critical window between movement onset in the gesture modality and onset of the spoken referent in speech.</div></div><div><h3>Results</h3><div>Both participants with and without TBI were more likely to fixate the target when the speaker produced a gesture compared to a grooming movement; however, relative to non-injured participants, the effect was significantly attenuated in the TBI group.</div></div><div><h3>Discussion</h3><div>We demonstrated evidence of reduced speech-gesture integration in participants with TBI relative to non-injured peers. This study advances our understanding of the communicative abilities of adults with TBI and could lead to a more mechanistic account of the communication difficulties adults with TBI experience in rich communication contexts that require the processing and integration of multiple co-occurring cues. This work has the potential to increase the ecological validity of language assessment and provide insights into the cognitive and neural mechanisms that support multimodal language processing.</div></div>","PeriodicalId":10758,"journal":{"name":"Cortex","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142568031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hippocampus supports long-term maintenance of language representations: Evidence of impaired collocation knowledge in amnesia. 海马支持语言表征的长期保持:失忆症患者搭配知识受损的证据
IF 3.2 2区 心理学 Q1 BEHAVIORAL SCIENCES Pub Date : 2024-10-22 DOI: 10.1016/j.cortex.2024.09.012
Natalie V Covington, Melissa C Duff

Traditional systems consolidation theories of memory suggest that the role of the hippocampus in maintaining memory representations diminishes over time, with learned information eventually becoming fully independent of the hippocampus. Knowledge of collocations in one's native (L1) language are acquired during development and are solidly acquired by adulthood. Remote semantic knowledge of collocations might therefore be expected to be resistant to hippocampal pathology. Patients with hippocampal damage and severe anterograde amnesia completed two tasks testing English collocation knowledge originally designed for use with English language learners. Patients with hippocampal damage demonstrated impairments in recognition of common English collocations, despite a lifetime of language experience (including postsecondary education) prior to sustaining this damage. These results suggest the hippocampus contributes to the long-term maintenance of linguistic representations and provides a challenge to traditional consolidation views of memory and an extension of newer theories to include a role for the hippocampus in maintaining semantic memory.

传统的系统巩固记忆理论认为,海马体在维持记忆表象方面的作用会随着时间的推移而减弱,学习到的信息最终会完全独立于海马体。母语(L1)中的搭配知识是在发育过程中获得的,到成年时已牢固掌握。因此,我们可以预期,词汇搭配的远程语义知识不会受到海马体病变的影响。海马体受损和严重逆行性遗忘的患者完成了两项测试英语搭配知识的任务,这两项任务最初是为英语学习者设计的。海马体受损的患者在识别常见英语搭配方面表现出了障碍,尽管他们在受损之前已经有了终生的语言经验(包括中学后教育)。这些结果表明,海马体有助于语言表征的长期保持,并对传统的巩固记忆观点提出了挑战,同时也扩展了新理论,使海马体在保持语义记忆方面发挥作用。
{"title":"Hippocampus supports long-term maintenance of language representations: Evidence of impaired collocation knowledge in amnesia.","authors":"Natalie V Covington, Melissa C Duff","doi":"10.1016/j.cortex.2024.09.012","DOIUrl":"https://doi.org/10.1016/j.cortex.2024.09.012","url":null,"abstract":"<p><p>Traditional systems consolidation theories of memory suggest that the role of the hippocampus in maintaining memory representations diminishes over time, with learned information eventually becoming fully independent of the hippocampus. Knowledge of collocations in one's native (L1) language are acquired during development and are solidly acquired by adulthood. Remote semantic knowledge of collocations might therefore be expected to be resistant to hippocampal pathology. Patients with hippocampal damage and severe anterograde amnesia completed two tasks testing English collocation knowledge originally designed for use with English language learners. Patients with hippocampal damage demonstrated impairments in recognition of common English collocations, despite a lifetime of language experience (including postsecondary education) prior to sustaining this damage. These results suggest the hippocampus contributes to the long-term maintenance of linguistic representations and provides a challenge to traditional consolidation views of memory and an extension of newer theories to include a role for the hippocampus in maintaining semantic memory.</p>","PeriodicalId":10758,"journal":{"name":"Cortex","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142590401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Alterations of the pulvinar in posterior cortical atrophy: A multimodal MRI study. 后皮质萎缩中的脉络膜变化:多模态磁共振成像研究
IF 3.2 2区 心理学 Q1 BEHAVIORAL SCIENCES Pub Date : 2024-10-19 DOI: 10.1016/j.cortex.2024.08.007
Jun Wang, Wuhai Tao, Min Chu, Deming Jiang, Li Liu, Yue Cui, Yang Liu, Yihao Wang, Ying Han, Caishui Yang, Liyong Wu

Background: Although the pulvinar is known for its visual function and extensive connections with cortical areas, the volumetric change and functional connectivity of the pulvinar in posterior cortical atrophy (PCA) remain unclear.

Objective: To identify functional and volumetric changes of the pulvinar in PCA patients and the relevant associations with higher visual dysfunction.

Methods: A total of 29 patients with PCA and 30 normal controls were recruited. Each participant underwent a comprehensive neuropsychological assessment and both structural and resting-state functional MRI scanning. Voxel-based morphometry (VBM) and seed-based functional connectivity analyses were conducted to assess pulvinar gray matter volume as well as functional connectivity between the pulvinar and whole brain regions. A partial correlation analysis was performed to analyze neuropsychological tests and pulvinar imaging data.

Results: Cognitive and visual functions including visuospatial processing, visual perception, episodic memory, and naming were impaired among PCA patients. Marked pulvinar atrophy was noted in PCA patients. Furthermore, functional connectivity between the pulvinar and precuneus was significantly decreased in PCA patients as compared to normal controls (FWE corrected; P < .001). Gray matter volume of the left pulvinar was found to associate with object agnosia (r = .53, P = .005) and prosopagnosia (r = .54, P = .005) among PCA patients. Gray matter volume of the right pulvinar was found to be associated with the Clinical Dementia Rating scale (r = -.52, P = .006) and Activities of Daily Living (r = -.59, P = .002) scores. Prosopagnosia correlated positively to the functional connectivity of the left pulvinar and left middle temporal.

Conclusion: Our findings support pulvinar degeneration and its contributions in PCA.

背景:尽管脉管以其视觉功能和与皮质区域的广泛联系而闻名,但后皮质萎缩(PCA)患者脉管的体积变化和功能联系仍不清楚:目的:确定PCA患者脉络膜的功能和体积变化,以及与较高视觉功能障碍的相关性:方法:共招募了29名PCA患者和30名正常对照者。方法:共招募了29名PCA患者和30名正常对照者,每位患者都接受了全面的神经心理学评估以及结构性和静息状态功能性磁共振成像扫描。通过基于体素的形态计量(VBM)和基于种子的功能连接分析来评估脉络膜灰质体积以及脉络膜与整个大脑区域之间的功能连接。对神经心理测试和脉管成像数据进行了部分相关性分析:结果:PCA 患者的认知和视觉功能,包括视觉空间处理、视觉感知、外显记忆和命名均受到损害。PCA患者的脉管明显萎缩。此外,与正常对照组相比,PCA 患者的脉轮和楔前肌之间的功能连接显著减少(FWE 校正;P 结论:PCA 患者的脉轮和楔前肌之间的功能连接显著减少:我们的研究结果证实了脉管退化及其在 PCA 中的作用。
{"title":"Alterations of the pulvinar in posterior cortical atrophy: A multimodal MRI study.","authors":"Jun Wang, Wuhai Tao, Min Chu, Deming Jiang, Li Liu, Yue Cui, Yang Liu, Yihao Wang, Ying Han, Caishui Yang, Liyong Wu","doi":"10.1016/j.cortex.2024.08.007","DOIUrl":"https://doi.org/10.1016/j.cortex.2024.08.007","url":null,"abstract":"<p><strong>Background: </strong>Although the pulvinar is known for its visual function and extensive connections with cortical areas, the volumetric change and functional connectivity of the pulvinar in posterior cortical atrophy (PCA) remain unclear.</p><p><strong>Objective: </strong>To identify functional and volumetric changes of the pulvinar in PCA patients and the relevant associations with higher visual dysfunction.</p><p><strong>Methods: </strong>A total of 29 patients with PCA and 30 normal controls were recruited. Each participant underwent a comprehensive neuropsychological assessment and both structural and resting-state functional MRI scanning. Voxel-based morphometry (VBM) and seed-based functional connectivity analyses were conducted to assess pulvinar gray matter volume as well as functional connectivity between the pulvinar and whole brain regions. A partial correlation analysis was performed to analyze neuropsychological tests and pulvinar imaging data.</p><p><strong>Results: </strong>Cognitive and visual functions including visuospatial processing, visual perception, episodic memory, and naming were impaired among PCA patients. Marked pulvinar atrophy was noted in PCA patients. Furthermore, functional connectivity between the pulvinar and precuneus was significantly decreased in PCA patients as compared to normal controls (FWE corrected; P < .001). Gray matter volume of the left pulvinar was found to associate with object agnosia (r = .53, P = .005) and prosopagnosia (r = .54, P = .005) among PCA patients. Gray matter volume of the right pulvinar was found to be associated with the Clinical Dementia Rating scale (r = -.52, P = .006) and Activities of Daily Living (r = -.59, P = .002) scores. Prosopagnosia correlated positively to the functional connectivity of the left pulvinar and left middle temporal.</p><p><strong>Conclusion: </strong>Our findings support pulvinar degeneration and its contributions in PCA.</p>","PeriodicalId":10758,"journal":{"name":"Cortex","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142496524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
On the road with Cortex. 与 Cortex 一起上路
IF 3.2 2区 心理学 Q1 BEHAVIORAL SCIENCES Pub Date : 2024-10-19 DOI: 10.1016/j.cortex.2024.10.001
Roberto Cubelli
{"title":"On the road with Cortex.","authors":"Roberto Cubelli","doi":"10.1016/j.cortex.2024.10.001","DOIUrl":"https://doi.org/10.1016/j.cortex.2024.10.001","url":null,"abstract":"","PeriodicalId":10758,"journal":{"name":"Cortex","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142568030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Cortex
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1