美国癌症基因组学“做得好”?评估实践跨越边界的研究和护理在农村社区肿瘤。

IF 1.3 4区 医学 Q4 BIOTECHNOLOGY & APPLIED MICROBIOLOGY New Genetics and Society Pub Date : 2022-01-01 DOI:10.1080/14636778.2022.2091532
Katherine Weatherford Darling, Michael Kohut, Susan Leeds, Eric C Anderson, Paul K J Han
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引用次数: 0

摘要

基因组肿瘤检测(GTT)是肿瘤学“实验护理”的新兴领域[Cambrosio, Alberto, Peter Keating, Etienne vignola - gagn, Sylvain Besle和Pascale Bourret. 2018a]。扩展实验:肿瘤学研究与护理之间逐渐消失的界限中国生物医学工程学报,37(3):444 - 444。doi: 10.1080 / 14636778.2018.1487281]。实施GTT的努力很少达到社区肿瘤学实践或生活在美国农村社区的患者。借鉴美国缅因州农村地区一项全州范围的癌症基因组学倡议的跨学科研究,本文探讨了社区肿瘤学家和癌症利益相关者在基因组科学和护理中“做好事”的评估实践。我们通过强调经济和非经济价值管理策略的情感维度,为STS关于生物经济的文献做出贡献。临床医生和利益相关者在“为缅因州”建立地方基因组平台的过程中,就去经济化和资本化模式进行了谈判。这些通过癌症基因组学做好事和感觉良好的定位模式,塑造了他们如何跨越研究和护理的界限,在美国生物医学市场的伦理模糊性中导航。
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"Doing Good" in U.S. Cancer Genomics? Valuation practices across the boundaries of research and care in rural community oncology.

Genomic Tumour Testing (GTT) is an emerging site of "experimental care" in oncology [Cambrosio, Alberto, Peter Keating, Etienne Vignola-Gagné, Sylvain Besle, and Pascale Bourret. 2018a. "Extending Experimentation: Oncology's Fading Boundary Bbetween Research and Care." New Genetics and Society 37 (3): 207-226. doi: 10.1080/14636778.2018.1487281]. Few efforts to implement GTT have reached community oncology practices or patients living in rural communities within the US. Drawing on interdisciplinary research on a state-wide cancer genomics initiative in the rural US state of Maine, this paper explores the valuation practices within community oncologist and cancer stakeholders accounts of "doing good" within genomic science and care. We contribute to STS literatures on the bio-economy by highlighting the affective dimensions of strategies for managing economic and non-economic values. Clinician and stakeholders negotiated de-economizing and capitalizing modes of doing good as they built local genomic platforms "for Maine." These situated modes of doing good and feeling good via cancer genomics shaped how they navigated the ethical ambiguities of US biomedical markets across the boundaries of research and care.

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来源期刊
New Genetics and Society
New Genetics and Society 生物-生物工程与应用微生物
CiteScore
4.30
自引率
16.70%
发文量
19
审稿时长
>12 weeks
期刊介绍: New Genetics and Society: Critical Studies of Contemporary Biosciences is a world-leading journal which: -Provides a focus for interdisciplinary and multi-disciplinary, leading-edge social science research on the new genetics and related biosciences; -Publishes theoretical and empirical contributions reflecting its multi-faceted development; -Provides an international platform for critical reflection and debate; -Is an invaluable research resource for the many related professions, including health, medicine and the law, wishing to keep abreast of fast changing developments in contemporary biosciences. New Genetics and Society publishes papers on the social aspects of the new genetics (widely defined), including gene editing, genomics, proteomics, epigenetics and systems biology; and the rapidly developing biosciences such as biomedical and reproductive therapies and technologies, xenotransplantation, stem cell research and neuroscience. Our focus is on developing a better understanding of the social, legal, ethical and policy aspects, including their local and global management and organisation.
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