马德里 COVID-19 结果中拉美移民与西班牙本地人之间的差异。

IF 4.9 4区 医学 Q1 PARASITOLOGY Pathogens and Global Health Pub Date : 2023-09-01 Epub Date: 2023-02-12 DOI:10.1080/20477724.2023.2174295
Begoña de Dios, Asunción Pérez-Jacoiste, Antonio Lalueza, Guillermo Maestro, Ana García-Reyne, Manuel Lizasoain, Carlos Lumbreras
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引用次数: 0

摘要

以往的研究表明,某些人群对 COVID-19 的易感性更高。我们分析了拉美裔移民和西班牙本地人之间 COVID-19 的发病率和死亡率是否存在差异:我们对 2020 年 1 月 26 日至 5 月 5 日期间收治的 35-64 岁 COVID-19 患者进行了回顾性研究。记录了入院时的人口统计学特征、主要合并症、症状、体征和分析参数。呼吸衰竭的定义是:PaO2/FiO2 ≤ 200 mmHg、住院期间任何时候需要无创或有创机械通气。在拉丁裔和西班牙裔之间进行了倾向评分(PS)调整。通过 PS 调整后的多变量逻辑回归模型来评估不同变量对死亡率的影响:894名患者:结果:共纳入 894 名患者:425 名拉丁裔(47.5%)和 469 名西班牙裔(52.5%)。拉丁裔患者更年轻(50 岁对 55 岁 p p = 0.018),炎症指标(PCR)更高(11.3 mg/dl 对 7.7 mg/dl p p = 0.017)。种族与死亡率之间没有关联。呼吸衰竭[OR = 23.978 (CI 95% 9.4-60.1) p p = 0.036]和 PCR [OR (每单位增量) = 1.044 (CI95% 1.06-1.08); p = 0.02]与死亡率独立相关:结论:在 COVID-19 死亡率方面,我们未能发现拉美裔与西班牙裔之间存在明显的种族差异。西班牙医疗保健系统的普及可能有助于改善拉丁裔患者的预后。之前描述的差异可能是社会经济差异造成的。
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Disparities between Latinx migrants and Spanish natives in COVID-19 outcome in Madrid.

Previous studies have suggested an increased susceptibility of COVID-19 among certain populations. We analyzed whether COVID-19 presentation and mortality differ between Latinx migrants and Spanish natives.

Methods and materials: COVID-19 patients between 35-64 years old admitted between January 26th-May-5th 2020 were reviewed. Demographics, major comorbidities, symptoms, signs and analytical parameters on admission were recorded. Respiratory failure was defined as PaO2/FiO2 ≤ 200 mmHg, noninvasive or invasive mechanical ventilation requirement at any time during hospitalization. A propensity score (PS) adjustment was created between Latinx and Spanish. A multivariable logistic regression model adjusted by the PS was performed to evaluate the effects of different variables on mortality.

Results: 894 patients: 425 (47.5%) Latinx and 469 (52.5%) Spanish natives were included. Latinx were younger (50 vs 55 years p < 0.001) and had less comorbidities (29.4% vs 55.0% p < 0.001) than Spanish natives. More often they exhibited fever (22.1% vs 9.8% p = 0.018) and had higher inflammatory markers (PCR) (11.3 mg/dl vs 7.7 mg/dl p < 0.001). Mortality seemed lower among Latinx (4.7% vs 8.7%, p = 0.017). No association was found between ethnicity and mortality. Respiratory failure [OR = 23.978 (CI 95% 9.4-60.1) p < 0.001], LDH [OR (per unitary increment) = 1.002; CI95% (1.000-1.004;p = 0.036] and PCR [OR (per unitary increment) = 1.044 (CI95% 1.06-1.08); p = 0.02] were independently associated to mortality.

Conclusions: We were unable to identify significant ethnic disparities between Latinx and Spanish natives in terms of COVID-19 mortality. Universal access to the health care system in Spain may have contributed to a better outcome of Latinx patients. Differences previously described might be a consequence of socioeconomic disparities.

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来源期刊
Pathogens and Global Health
Pathogens and Global Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-PARASITOLOGY
CiteScore
6.00
自引率
0.00%
发文量
60
审稿时长
6-12 weeks
期刊介绍: Pathogens and Global Health is a journal of infectious disease and public health that focuses on the translation of molecular, immunological, genomics and epidemiological knowledge into control measures for global health threat. The journal publishes original innovative research papers, reviews articles and interviews policy makers and opinion leaders on health subjects of international relevance. It provides a forum for scientific, ethical and political discussion of new innovative solutions for controlling and eradicating infectious diseases, with particular emphasis on those diseases affecting the poorest regions of the world.
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