{"title":"黑人参中一种新的达玛烷类三萜皂苷的结构阐释和核磁共振谱定位","authors":"Xue-Ting Zhao , De-Qiang Dou , Yang Qu , Guo-Gang Zhang","doi":"10.1080/10286020.2023.2253153","DOIUrl":null,"url":null,"abstract":"<div><p>New dammarane-type triterpenoid saponin, named 22(<em>R</em>)-notoginsenoside Ab1 (<strong>1</strong>), together with thirteen known dammarane-type triterpenoid saponins (<strong>2</strong>-<strong>14</strong>) was isolated from the EtOH extract of black ginseng and their structures were elucidated on the basis of one- and two-dimensional NMR (including <sup>1</sup>H-NMR, <sup>13</sup>C-NMR, HSQC, HMBC, ROESY) and calculated ECD. Among them, compounds <strong>1-2</strong> and <strong>6</strong>-<strong>8</strong> were isolated for the first time from ginseng and black ginseng. Besides, the absolute structure of 22(<em>R</em>)- and 22(<em>S</em>)- notoginsenoside Ab1 were distinguished by ECD for the first time.</p></div>","PeriodicalId":15180,"journal":{"name":"Journal of Asian Natural Products Research","volume":null,"pages":null},"PeriodicalIF":1.3000,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Structure elucidation and NMR spectral assignments of one new dammarane-type triterpenoid saponin from black ginseng\",\"authors\":\"Xue-Ting Zhao , De-Qiang Dou , Yang Qu , Guo-Gang Zhang\",\"doi\":\"10.1080/10286020.2023.2253153\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>New dammarane-type triterpenoid saponin, named 22(<em>R</em>)-notoginsenoside Ab1 (<strong>1</strong>), together with thirteen known dammarane-type triterpenoid saponins (<strong>2</strong>-<strong>14</strong>) was isolated from the EtOH extract of black ginseng and their structures were elucidated on the basis of one- and two-dimensional NMR (including <sup>1</sup>H-NMR, <sup>13</sup>C-NMR, HSQC, HMBC, ROESY) and calculated ECD. Among them, compounds <strong>1-2</strong> and <strong>6</strong>-<strong>8</strong> were isolated for the first time from ginseng and black ginseng. Besides, the absolute structure of 22(<em>R</em>)- and 22(<em>S</em>)- notoginsenoside Ab1 were distinguished by ECD for the first time.</p></div>\",\"PeriodicalId\":15180,\"journal\":{\"name\":\"Journal of Asian Natural Products Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2024-05-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Asian Natural Products Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/org/science/article/pii/S1028602023002436\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, APPLIED\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Asian Natural Products Research","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/org/science/article/pii/S1028602023002436","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
Structure elucidation and NMR spectral assignments of one new dammarane-type triterpenoid saponin from black ginseng
New dammarane-type triterpenoid saponin, named 22(R)-notoginsenoside Ab1 (1), together with thirteen known dammarane-type triterpenoid saponins (2-14) was isolated from the EtOH extract of black ginseng and their structures were elucidated on the basis of one- and two-dimensional NMR (including 1H-NMR, 13C-NMR, HSQC, HMBC, ROESY) and calculated ECD. Among them, compounds 1-2 and 6-8 were isolated for the first time from ginseng and black ginseng. Besides, the absolute structure of 22(R)- and 22(S)- notoginsenoside Ab1 were distinguished by ECD for the first time.
期刊介绍：
The Journal of Asian Natural Products Research (JANPR) publishes chemical and pharmaceutical studies in the English language in the field of natural product research on Asian ethnic medicine. The journal publishes work from scientists in Asian countries, e.g. China, Japan, Korea and India, including contributions from other countries concerning natural products of Asia. The journal is chemistry-orientated. Major fields covered are: isolation and structural elucidation of natural constituents (including those for non-medical uses), synthesis and transformation (including biosynthesis and biotransformation) of natural products, pharmacognosy, and allied topics. Biological evaluation of crude extracts are acceptable only as supporting data for pure isolates with well-characterized structures.
All published research articles in this journal have undergone rigorous peer review, based on initial editor screening and anonymized refereeing by at least two expert referees.
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