住院痴呆症患者在用药方面的性别和种族差异。

IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Journal of Racial and Ethnic Health Disparities Pub Date : 2024-10-01 Epub Date: 2023-08-14 DOI:10.1007/s40615-023-01745-9
Barbara Resnick, Marie Boltz, Elizabeth Galik, Ashley Kuzmik, Rachel McPherson, Brittany Drazich, Nayeon Kim, Shijun Zhu, Chris L Wells
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引用次数: 0

摘要

本研究的目的是描述白人与黑人老年人、男性与女性老年人,以及居住在家中、辅助生活或养老院社区的老年人在使用精神药物、止痛药和心血管药物方面的治疗差异。本研究使用了首批 352 名参与者的基线数据,这些数据来自于 "使用证据整合三角 "对急性期护理实施的 "以功能为重点的护理"。数据包括年龄、性别、种族、合并症、入院诊断、住院前居住地、圣路易斯大学精神状态检查、改良查尔森合并症指数、晚期痴呆疼痛评估量表、意识模糊评估方法和处方药物。进行了广义线性混合模型分析,控制了种族或性别(取决于进行哪种比较分析)、年龄、认知状态、医院、谵妄和合并症。与黑人老年人相比,白人老年人在抗抑郁药、抗焦虑药、非阿片类止痛药和阿片类药物方面的用药量明显较高,而在降压药方面的用药量较低。女性比男性服用更多抗焦虑药。在非阿片类止痛药、抗精神病药、他汀类药物和抗凝血剂方面,不同居住地的用药情况存在差异。研究结果提供了一些关于不同人群用药差异的最新信息,有助于指导未来的研究和假设检验,以尽量减少这些治疗差异。
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Differences in Medication Use by Gender and Race in Hospitalized Persons Living with Dementia.

The purpose of this study was to describe differences in treatment of White versus Black older adults, males versus females, and those living at home, assisted living, or nursing home communities with regard to the use of psychotropic, pain, and cardiovascular medications. Baseline data from the first 352 participants in the study, implementation of Function-Focused Care for Acute Care Using the Evidence Integration Triangle, were used. Data included age, gender, race, comorbidities, admission diagnosis, and living location prior to hospitalization, the Saint Louis University Mental Status exam, the modified Charlson Comorbidity Index, the Pain Assessment in Advanced Dementia scale, the Confusion Assessment Method, and medications prescribed. Generalized linear mixed model analyses were done, controlling for race or gender (depending on which comparison analysis was being done), age, cognitive status, hospital, delirium, and comorbidities. Medication use was significantly higher for White older adults, compared to Black older adults, for antidepressants, anxiolytics, non-opioid pain medications, and opioids and lower for antihypertensives. Females received more anxiolytics than their male counterparts. There were differences in medication use by living location with regard to non-opioid pain medication, antipsychotics, statins, and anticoagulants. The findings provide some current information about differences in medication use across groups of individuals and can help guide future research and hypothesis testing for approaches to minimizing these differences in treatment.

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来源期刊
Journal of Racial and Ethnic Health Disparities
Journal of Racial and Ethnic Health Disparities PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
7.30
自引率
5.10%
发文量
263
期刊介绍: Journal of Racial and Ethnic Health Disparities reports on the scholarly progress of work to understand, address, and ultimately eliminate health disparities based on race and ethnicity. Efforts to explore underlying causes of health disparities and to describe interventions that have been undertaken to address racial and ethnic health disparities are featured. Promising studies that are ongoing or studies that have longer term data are welcome, as are studies that serve as lessons for best practices in eliminating health disparities. Original research, systematic reviews, and commentaries presenting the state-of-the-art thinking on problems centered on health disparities will be considered for publication. We particularly encourage review articles that generate innovative and testable ideas, and constructive discussions and/or critiques of health disparities.Because the Journal of Racial and Ethnic Health Disparities receives a large number of submissions, about 30% of submissions to the Journal are sent out for full peer review.
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