大鼠更喜欢炼乳而不是草莓酱--自愿口服药物的一种新可能性。

IF 1.3 4区 农林科学 Q2 VETERINARY SCIENCES Laboratory Animals Pub Date : 2024-04-01 Epub Date: 2023-09-15 DOI:10.1177/00236772231194389
Mariana Ferreira-Duarte, Igor Moreira Lopes, Manuela Morato, Margarida Duarte-Araújo
{"title":"大鼠更喜欢炼乳而不是草莓酱--自愿口服药物的一种新可能性。","authors":"Mariana Ferreira-Duarte, Igor Moreira Lopes, Manuela Morato, Margarida Duarte-Araújo","doi":"10.1177/00236772231194389","DOIUrl":null,"url":null,"abstract":"<p><p>Voluntary oral drug administration using sweet substances promotes rodents' therapeutic compliance while reducing stress induced by forced drug administration. We aimed to test whether rats would willingly eat strawberry jam or condensed milk from a syringe, and which one they would prefer. Our results show that rats prefer condensed milk, demonstrating its potential as a vehicle for the voluntary oral administration of drugs in experimental protocols.</p>","PeriodicalId":18013,"journal":{"name":"Laboratory Animals","volume":null,"pages":null},"PeriodicalIF":1.3000,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Rats prefer condensed milk to strawberry jam - a new possibility for voluntary oral drug administration.\",\"authors\":\"Mariana Ferreira-Duarte, Igor Moreira Lopes, Manuela Morato, Margarida Duarte-Araújo\",\"doi\":\"10.1177/00236772231194389\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Voluntary oral drug administration using sweet substances promotes rodents' therapeutic compliance while reducing stress induced by forced drug administration. We aimed to test whether rats would willingly eat strawberry jam or condensed milk from a syringe, and which one they would prefer. Our results show that rats prefer condensed milk, demonstrating its potential as a vehicle for the voluntary oral administration of drugs in experimental protocols.</p>\",\"PeriodicalId\":18013,\"journal\":{\"name\":\"Laboratory Animals\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2024-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Laboratory Animals\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1177/00236772231194389\",\"RegionNum\":4,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2023/9/15 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"VETERINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Laboratory Animals","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/00236772231194389","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/9/15 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
引用次数: 0

摘要

使用甜味物质进行自愿口服给药可提高啮齿动物的治疗依从性,同时减少强制给药引起的应激反应。我们的目的是测试大鼠是否愿意从注射器中吃草莓酱或炼乳,以及它们更喜欢哪一种。我们的结果表明,大鼠更喜欢炼乳,这表明炼乳有可能成为实验方案中自愿口服给药的载体。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Rats prefer condensed milk to strawberry jam - a new possibility for voluntary oral drug administration.

Voluntary oral drug administration using sweet substances promotes rodents' therapeutic compliance while reducing stress induced by forced drug administration. We aimed to test whether rats would willingly eat strawberry jam or condensed milk from a syringe, and which one they would prefer. Our results show that rats prefer condensed milk, demonstrating its potential as a vehicle for the voluntary oral administration of drugs in experimental protocols.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Laboratory Animals
Laboratory Animals 生物-动物学
CiteScore
4.90
自引率
8.30%
发文量
64
审稿时长
6-12 weeks
期刊介绍: The international journal of laboratory animal science and welfare, Laboratory Animals publishes peer-reviewed original papers and reviews on all aspects of the use of animals in biomedical research. The journal promotes improvements in the welfare or well-being of the animals used, it particularly focuses on research that reduces the number of animals used or which replaces animal models with in vitro alternatives.
期刊最新文献
An innovative approach for health and safety training and occupational health program annual enrollment for laboratory animal care and use personnel. Extended oxygen supplementation after thoracotomy in rats may improve welfare. Animal researchers' views on the publication of negative results and subsequent policy adoptions. Spontaneous hepatocellular and gastric tumours in African clawed frogs (Xenopus laevis). Single nucleotide polymorphism (SNP) characterisation of mouse inbred strains bred at MRC-National Institute for Medical Research.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1