{"title":"虚拟压力对细胞起作用。","authors":"Alexander Loewer","doi":"10.1016/j.cels.2023.06.006","DOIUrl":null,"url":null,"abstract":"<p><p>Optogenetics enables the induction of virtual stress, which separates stress signaling from cellular damage. This provides new insights into the dynamics of the integrated stress response and reveals the mechanisms through which cells form memories of past stress events to guide their response to acute stress.</p>","PeriodicalId":54348,"journal":{"name":"Cell Systems","volume":null,"pages":null},"PeriodicalIF":9.0000,"publicationDate":"2023-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Virtual stress plays tricks on cells.\",\"authors\":\"Alexander Loewer\",\"doi\":\"10.1016/j.cels.2023.06.006\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Optogenetics enables the induction of virtual stress, which separates stress signaling from cellular damage. This provides new insights into the dynamics of the integrated stress response and reveals the mechanisms through which cells form memories of past stress events to guide their response to acute stress.</p>\",\"PeriodicalId\":54348,\"journal\":{\"name\":\"Cell Systems\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":9.0000,\"publicationDate\":\"2023-07-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cell Systems\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.1016/j.cels.2023.06.006\",\"RegionNum\":1,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"BIOCHEMISTRY & MOLECULAR BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cell Systems","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1016/j.cels.2023.06.006","RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
Optogenetics enables the induction of virtual stress, which separates stress signaling from cellular damage. This provides new insights into the dynamics of the integrated stress response and reveals the mechanisms through which cells form memories of past stress events to guide their response to acute stress.
Cell SystemsMedicine-Pathology and Forensic Medicine
CiteScore
16.50
自引率
1.10%
发文量
84
审稿时长
42 days
期刊介绍：
In 2015, Cell Systems was founded as a platform within Cell Press to showcase innovative research in systems biology. Our primary goal is to investigate complex biological phenomena that cannot be simply explained by basic mathematical principles. While the physical sciences have long successfully tackled such challenges, we have discovered that our most impactful publications often employ quantitative, inference-based methodologies borrowed from the fields of physics, engineering, mathematics, and computer science. We are committed to providing a home for elegant research that addresses fundamental questions in systems biology.
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