An overview of Helium-3 NMR: Recent developments and applications

The present review is focused on experimental and theoretical methods together with applications of helium NMR in chemistry and biochemistry. It comprises two main sections, the first dealing with standardization and instrumentation for ³He NMR spectroscopy and the second dealing with its practical applications, mainly those in general and organic chemistry with a special emphasis on the rapidly developing and exciting area of fullerenes encapsulating helium atoms. Several general applications of ³He NMR spectroscopy in physical chemistry and biomedicine are also briefly discussed.