微生物群组成的扰动作为神经精神、神经和精神疾病的新媒介:平衡变化的预防和治疗性补充疗法。

IF 1.8 4区 医学 Q3 CLINICAL NEUROLOGY Current Alzheimer research Pub Date : 2023-01-01 DOI:10.2174/1567205020666230718160914
Majid Taati Moghadam, Andrés Alexis Ramírez-Coronel, Samaneh Darijani, Majid Reza Akbarizadeh, Mahin Naderifar, Simin Soltaninejad, Shahla Shahbazi, Amin Sadeghi Dousari, Ali Mojtahedi, Reza Akhavan-Sigari
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引用次数: 1

摘要

虽然微生物学和神经学是不同的学科,但它们与一些传染病和神经系统疾病有关。目前,微生物组被许多研究者认为是健康的生物标志物之一。这导致了微生物组变化与许多神经系统疾病的关联。天然微生物群有许多有益的特性。如果被破坏和改变,它会导致不可逆转的并发症和许多神经系统疾病。因此,根据以往的研究,一些预防性和治疗性的补充疗法可以预防或恢复神经系统的微生物群失调和炎症。根据我们目前对不同神经系统疾病的微生物基础的认识,应该考虑药物治疗和控制微生物组扰动的两个方面,同时针对它们可能有助于获得有利的结果。
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Perturbations in Microbiota Composition as a Novel Mediator in Neuropsychiatric, Neurological and Mental Disorders: Preventive and Therapeutic Complementary Therapies to Balance the Change.

Although microbiology and neurology are separate disciplines, they are linked to some infectious and neurological diseases. Today, microbiome is considered as one of the biomarkers of health by many researchers. This has led to the association of microbiome changes with many neurological diseases. The natural microbiota has many beneficial properties. If disrupted and altered, it can lead to irreversible complications and many neurological diseases. Therefore, according to previous studies, some preventive and therapeutic complementary therapies can prevent or restore microbiome dysbiosis and inflammation in the nervous system. With our current perception of the microbiological basis for different neurological disorders, both aspects of drug treatment and control of perturbations of the microbiome should be considered, and targeting them simultaneously will likely help to attain favorable results.

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来源期刊
Current Alzheimer research
Current Alzheimer research 医学-神经科学
CiteScore
4.00
自引率
4.80%
发文量
64
审稿时长
4-8 weeks
期刊介绍: Current Alzheimer Research publishes peer-reviewed frontier review, research, drug clinical trial studies and letter articles on all areas of Alzheimer’s disease. This multidisciplinary journal will help in understanding the neurobiology, genetics, pathogenesis, and treatment strategies of Alzheimer’s disease. The journal publishes objective reviews written by experts and leaders actively engaged in research using cellular, molecular, and animal models. The journal also covers original articles on recent research in fast emerging areas of molecular diagnostics, brain imaging, drug development and discovery, and clinical aspects of Alzheimer’s disease. Manuscripts are encouraged that relate to the synergistic mechanism of Alzheimer''s disease with other dementia and neurodegenerative disorders. Book reviews, meeting reports and letters-to-the-editor are also published. The journal is essential reading for researchers, educators and physicians with interest in age-related dementia and Alzheimer’s disease. Current Alzheimer Research provides a comprehensive ''bird''s-eye view'' of the current state of Alzheimer''s research for neuroscientists, clinicians, health science planners, granting, caregivers and families of this devastating disease.
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