沐浴法与干法对早期新生儿皮肤状况影响的前瞻性观察研究。

IF 1.5 4区 医学 Q3 DERMATOLOGY Annals of Dermatology Pub Date : 2023-08-01 DOI:10.5021/ad.22.098
Sachi Higuchi, Seiichi Yoshida, Takeo Minematsu, Yutaka Hatano, Akifumi Notsu, Takamichi Ichinose
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引用次数: 0

摘要

背景:在日本,新生儿通常在出生后立即在浴缸里洗澡,因为洗澡是清洁杂质的习俗。然而,自2000年以来,干式技术已被引入许多机构。关于这两种方法对新生儿皮肤的有益或有害的科学证据很少,因此,关于哪种方法更好的意见仍然存在分歧。目的:本研究的目的是确定沐浴或干式清洁技术在维持新生儿早期皮肤健康方面是否更好。方法:测定各组经皮失水(TEWL)和皮肤pH值,作为皮肤屏障功能的指标。肿瘤坏死因子(TNF)- α和白细胞介素(IL)-6是角质形成细胞释放的炎症细胞因子,采用皮肤印迹法测定。结果:干法新生儿TEWL和皮肤pH值低于沐浴法。洗浴组新生儿胸部皮肤IL-6、TNF-α表达水平高于干法组。结论:在新生儿早期,干燥法比沐浴法能更好地保持皮肤健康。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Comparison of the Effects of Bathing and the Dry Technique on the Skin Condition of Early Neonates: A Prospective Observational Study.

Background: In Japan, neonates have typically been bathed in a bathtub immediately after birth because bathing is a custom for cleansing impurities. However, dry technique has been introduced into many institutions since 2000. There is little scientific evidence on the benefit or harmfulness of either method to neonatal skin, and consequently, opinion remains split on which method is superior.

Objective: The purpose of the present study was to determine whether bathing or the dry technique of cleaning is better in maintaining skin health in the early neonatal period.

Methods: Transepidermal water loss (TEWL) and skin pH, considered an index of skin barrier function, were measured in each group. Tumor necrosis factor (TNF)-alpha and interleukin (IL)-6, which are inflammatory cytokines released by keratinocytes, were measured by skin blotting.

Results: TEWL and skin pH of neonates were lower with the dry technique than with bathing. The expression level of IL-6 and TNF-α in chest skin of neonates was higher with bathing than with the dry technique.

Conclusion: These results suggest that the dry technique may maintain skin health better than bathing in the early neonatal period.

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来源期刊
Annals of Dermatology
Annals of Dermatology 医学-皮肤病学
CiteScore
1.60
自引率
6.20%
发文量
77
审稿时长
6-12 weeks
期刊介绍: Annals of Dermatology (Ann Dermatol) is the official peer-reviewed publication of the Korean Dermatological Association and the Korean Society for Investigative Dermatology. Since 1989, Ann Dermatol has contributed as a platform for communicating the latest research outcome and recent trend of dermatology in Korea and all over the world. Ann Dermatol seeks for ameliorated understanding of skin and skin-related disease for clinicians and researchers. Ann Dermatol deals with diverse skin-related topics from laboratory investigations to clinical outcomes and invites review articles, original articles, case reports, brief reports and items of correspondence. Ann Dermatol is interested in contributions from all countries in which good and advanced research is carried out. Ann Dermatol willingly recruits well-organized and significant manuscripts with proper scope throughout the world.
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