老年髋部骨折患者的高死亡率:印度经验

IF 1.8 4区 医学 Q2 ORTHOPEDICS Chinese Journal of Traumatology Pub Date : 2023-11-01 DOI:10.1016/j.cjtee.2023.06.004
Jaiben George, Vijay Sharma, Kamran Farooque, Vivek Trikha, Samarth Mittal, Rajesh Malhotra
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引用次数: 0

摘要

目的:老年人髋部骨折死亡率高。然而,与正常人群相比,关于髋部骨折患者死亡率过高的文献有限。本研究的目的是比较髋部骨折的死亡率与年龄和性别匹配的印度人口的死亡率。方法对283例50岁以上单中心收治的髋部骨折患者进行前瞻性研究。随访1年,有随访记录279例。死亡率在随访期间通过图表回顾和/或电话访谈进行评估。从公共数据库获取印度人口一年死亡率。计算标准化死亡率(SMR)(观察死亡率除以预期死亡率)。采用Kaplan-Meir分析。结果1年总死亡率为19.0%(53/279)。死亡率随年龄增长而增加(p <0.001), 80岁以上人群死亡率最高(50 - 59岁:5.0%,60 - 69岁:19.7%,70 - 79岁:15.8%,80岁以上:33.3%)。年龄和性别相似的印度人口的预期死亡率为3.7%,SMR为5.5。不同年龄段的SMR分别为:3.9(50 ~ 59岁)、6.6(60 ~ 69岁)、2.2(70 ~ 79岁);2.0(80岁以上)。男性和女性的SMR分别为5.7和5.3。结论:印度髋部骨折患者的死亡率是普通人群的5倍。尽管死亡率随年龄增长而增加,但在相对年轻的患者中,超额死亡率最高。髋部骨折的死亡率甚至高于心肌梗死、乳腺癌和宫颈癌。
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Excess mortality in elderly hip fracture patients: An Indian experience

Purpose

Hip fractures in elderly have a high mortality. However, there is limited literature on the excess mortality seen in hip fractures compared to the normal population. The purpose of this study was to compare the mortality of hip fractures with that of age and gender matched Indian population.

Methods

There are 283 patients with hip fractures aged above 50 years admitted at single centre prospectively enrolled in this study. Patients were followed up for 1 year and the follow-up record was available for 279 patients. Mortality was assessed during the follow-up from chart review and/or by telephonic interview. One-year mortality of Indian population was obtained from public databases. Standardized mortality ratio (SMR) (observed mortality divided by expected mortality) was calculated. Kaplan-Meir analysis was used.

Results

The overall 1-year mortality was 19.0% (53/279). Mortality increased with age (p < 0.001) and the highest mortality was seen in those above 80 years (aged 50 – 59 years: 5.0%, aged 60 – 69 years: 19.7%, aged 70 – 79 years: 15.8%, and aged over 80 years: 33.3%). Expected mortality of Indian population of similar age and gender profile was 3.7%, giving a SMR of 5.5. SMR for different age quintiles were: 3.9 (aged 50 – 59 years), 6.6 (aged 60 – 69 years), 2.2 (aged 70 – 79 years); and 2.0 (aged over 80 years). SMR in males and females were 5.7 and 5.3, respectively.

Conclusions

Indian patients sustaining hip fractures were about 5 times more likely to die than the general population. Although mortality rates increased with age, the highest excess mortality was seen in relatively younger patients. Hip fracture mortality was even higher than that of myocardial infarction, breast cancer, and cervical cancer.

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来源期刊
CiteScore
3.80
自引率
4.80%
发文量
1707
审稿时长
28 weeks
期刊介绍: Chinese Journal of Traumatology (CJT, ISSN 1008-1275) was launched in 1998 and is a peer-reviewed English journal authorized by Chinese Association of Trauma, Chinese Medical Association. It is multidisciplinary and designed to provide the most current and relevant information for both the clinical and basic research in the field of traumatic medicine. CJT primarily publishes expert forums, original papers, case reports and so on. Topics cover trauma system and management, surgical procedures, acute care, rehabilitation, post-traumatic complications, translational medicine, traffic medicine and other related areas. The journal especially emphasizes clinical application, technique, surgical video, guideline, recommendations for more effective surgical approaches.
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