空气净化器降低澳大利亚老年护理机构急性呼吸道感染的发生率:一项随机对照试验的研究方案

IF 2.7 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Infection Disease & Health Pub Date : 2023-08-01 DOI:10.1016/j.idh.2023.05.006
Bismi Thottiyil Sultanmuhammed Abdul Khadar , Jenny Sim , Julee McDonagh , Vanessa M. McDonald , Brett G. Mitchell
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引用次数: 0

摘要

居住在安老院舍(RACFs)的成年人极易感染季节性呼吸道感染。有证据表明,室内密闭空间中被病毒颗粒污染的气溶胶可能在呼吸道感染的传播中发挥重要作用。在这份协议文件中,我们概述了一项计划中的随机对照试验的细节,该试验旨在评估便携式室内空气净化器在降低澳大利亚rac居民患急性呼吸道感染风险方面的有效性。本研究采用多中心双盲随机交叉设计。在新南威尔士州的一个区域,将邀请三个区域基金参与这项研究。有或没有高效微粒吸收(HEPA)过滤器的空气净化器将被放置在参加试验的居民的房间里。主要结果将是ARI发病率的降低,次要结果将是首次感染的时间、急诊入院次数、住院次数和因ARI就诊的医疗咨询。据我们所知,这将是首次在居民房间中使用空气净化器来确定其在减少rac中ARIs方面的效果的随机对照试验。如果我们的研究结果表明室内空气净化有一些潜在的好处,它将有助于为更大规模的试验提供支持和理由,其中可能包括设施范围内的空气净化方法。
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Air purifiers for reducing the incidence of acute respiratory infections in australian residential aged care facilities: A study protocol for a randomised control trial

Introduction

Adults living in Residential Aged Care Facilities (RACFs) are highly susceptible to seasonal respiratory infections. Evidence indicates that the aerosols contaminated with virus particles in closed indoor spaces may play a significant role in the transmission of respiratory infections. In this protocol paper, we outline details of a planned RCT which aims to evaluate the effectiveness of portable in room air purifiers in reducing the risk of ARIs among residents in Australian RACFs.

This study uses a multi-centre double-blind randomised crossover design. Three RACFs in a regional area of New South Wales will be invited to participate in the study. Air purifiers with or without high-efficiency particulate absorbing (HEPA) filters will be placed in the rooms of residents who are enrolled in the trial. The primary outcome will be a reduction in the incidence of ARI and the secondary outcomes will be the time to first infection, number of emergency department admissions, hospital admissions, and medical consultations due to an ARI.

Conclusion

To our knowledge, this will be the first RCT using air purifiers in resident rooms to identify their effect in reducing ARIs in RACFs. If our findings indicate some potential benefit for in-room air purification, it will help provide support and justification for larger trials, which may include a facility wide approach to air purification.

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来源期刊
Infection Disease & Health
Infection Disease & Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
5.70
自引率
5.70%
发文量
40
审稿时长
20 days
期刊介绍: The journal aims to be a platform for the publication and dissemination of knowledge in the area of infection and disease causing infection in humans. The journal is quarterly and publishes research, reviews, concise communications, commentary and other articles concerned with infection and disease affecting the health of an individual, organisation or population. The original and important articles in the journal investigate, report or discuss infection prevention and control; clinical, social, epidemiological or public health aspects of infectious disease; policy and planning for the control of infections; zoonoses; and vaccination related to disease in human health. Infection, Disease & Health provides a platform for the publication and dissemination of original knowledge at the nexus of the areas infection, Disease and health in a One Health context. One Health recognizes that the health of people is connected to the health of animals and the environment. One Health encourages and advances the collaborative efforts of multiple disciplines-working locally, nationally, and globally-to achieve the best health for people, animals, and our environment. This approach is fundamental because 6 out of every 10 infectious diseases in humans are zoonotic, or spread from animals. We would be expected to report or discuss infection prevention and control; clinical, social, epidemiological or public health aspects of infectious disease; policy and planning for the control of infections; zoonosis; and vaccination related to disease in human health. The Journal seeks to bring together knowledge from all specialties involved in infection research and clinical practice, and present the best work in this ever-changing field. The audience of the journal includes researchers, clinicians, health workers and public policy professionals concerned with infection, disease and health.
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