维生素D状况也会影响儿科人群的COVID-19结局

IF 2.4 Q3 NUTRITION & DIETETICS PharmaNutrition Pub Date : 2022-12-01 DOI:10.1016/j.phanu.2022.100319

Michele Miraglia del Giudice , Cristiana Indolfi , Giulio Dinardo , Fabio Decimo , Alberto Decimo , Angela Klain

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引用次数: 7

摘要

维生素D影响免疫系统和炎症反应。众所周知，补充维生素D可以降低急性呼吸道感染的风险。在过去的两年中，许多研究人员研究了维生素D在COVID-19疾病病理生理学中的作用。结果临床试验和系统评价的结果强调，大多数COVID-19患者维生素D水平降低，维生素D水平低会增加严重疾病的风险。这一证据似乎在儿科人群中也得到了证实。结论:需要对儿童进行进一步的研究(系统评价和荟萃分析)，以证实维生素D会影响COVID-19的结局，并确定补充维生素D的有效性以及适当的剂量、持续时间和给药方式。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Vitamin D status can affect COVID-19 outcomes also in pediatric population

Background

vitamin D influences the immune system and the inflammatory response. It is known that vitamin D supplementation reduces the risk of acute respiratory tract infection. In the last two years, many researchers have investigated vitamin D’s role in the pathophysiology of COVID-19 disease.

Results

the findings obtained from clinical trials and systematic reviews highlight that most patients with COVID-19 have decreased vitamin D levels and low levels of vitamin D increase the risk of severe disease. This evidence seems to be also confirmed in the pediatric population.

Conclusions

further studies (systematic review and meta-analysis) conducted on children are needed to confirm that vitamin D affects COVID-19 outcomes and to determine the effectiveness of supplementation and the appropriate dose, duration and mode of administration.

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