一项初步研究表明,接触暴力与情绪调节和认知控制中的神经连通性下降有关,但与工作记忆和社会经济地位后的网络无关。

IF 4.7 2区 心理学 Q1 BEHAVIORAL SCIENCES Behavioral and Brain Functions Pub Date : 2022-12-12 DOI:10.1186/s12993-022-00201-8
Samantha R Mattheiss, Hillary Levinson, Miriam Rosenberg-Lee, William W Graves
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引用次数: 0

摘要

先前的研究已经证明了与经历逆境有关的行为和神经差异。然而,逆境不太可能是一个单一的结构,我们期望研究更具体的因素的影响,如家庭社区中的暴力暴露,将产生更具体的可解释的结果。在这里,我们考虑了低社会经济地位(SES)的影响,以研究暴露于暴力对已知与情绪调节和工作记忆相关的大脑区域之间功能连接的具体影响。研究预测,儿童时期暴露于高水平暴力与低水平暴力的个体在静息状态下的功能连通性降低的两个区域是:(1)与情绪认知控制有关的双侧杏仁核前内侧区域;(2)与工作记忆有关的右背外侧前额叶皮层(dlPFC)与额叶和顶叶区域有关。与我们的预测一致,即使在考虑了SES之后,暴力暴露的增加与右杏仁核和前扣带皮层之间的静息状态功能连接的减少有关。同样,在考虑了SES之后,暴露于暴力与右侧dlPFC和额叶区域之间的连接减少有关,但与通常与工作记忆相关的顶叶区域无关。总的来说,这种模式表明,童年时期接触暴力的次数增加,与情绪调节和认知控制回路关键区域之间的连通性降低有关,但与工作记忆无关。这些结果提供了对与暴力接触相关的行为结果的神经基础的深入了解,为最终设计干预措施以解决这种接触的影响奠定了基础。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Exposure to violence is associated with decreased neural connectivity in emotion regulation and cognitive control, but not working memory, networks after accounting for socioeconomic status: a preliminary study.

Previous research has demonstrated behavioral and neural differences associated with experiencing adversity. However, adversity is unlikely to be a monolithic construct, and we expect that examining effects of more specific components such as exposure to violence in the home community will yield more concretely interpretable results. Here we account for effects of low socioeconomic status (SES) to examine the specific effects of exposure to violence on functional connectivity between brain areas known to be related to emotion regulation and working memory. Decreased resting state functional connectivity for individuals exposed to high compared to low levels of violence during childhood was predicted for two sets of areas: (1) bilateral amygdala with anterior medial regions involved in cognitive control of emotion, and (2) the right dorsolateral prefrontal cortex (dlPFC) with frontal and parietal regions implicated in working memory. Consistent with our predictions, increasing exposure to violence was related to decreased resting state functional connectivity between the right amygdala and anterior cingulate cortex, even after accounting for SES. Also after accounting for SES, exposure to violence was related to reductions in connectivity between the right dlPFC and frontal regions, but not with parietal regions typically associated with working memory. Overall, this pattern suggests increased exposure to violence in childhood is associated with reduced connectivity among key areas of the circuitry involved in emotion regulation and cognitive control, but not working memory. These results offer insight into the neural underpinnings of behavioral outcomes associated with exposure to violence, laying the foundation for ultimately designing interventions to address the effects of such exposure.

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来源期刊
Behavioral and Brain Functions
Behavioral and Brain Functions 医学-行为科学
CiteScore
5.90
自引率
0.00%
发文量
11
审稿时长
6-12 weeks
期刊介绍: A well-established journal in the field of behavioral and cognitive neuroscience, Behavioral and Brain Functions welcomes manuscripts which provide insight into the neurobiological mechanisms underlying behavior and brain function, or dysfunction. The journal gives priority to manuscripts that combine both neurobiology and behavior in a non-clinical manner.
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