世界上使用和滥用滤水烟斗的情况。对公共卫生、研究和研究伦理的影响。

Q2 Pharmacology, Toxicology and Pharmaceutics Open Medicinal Chemistry Journal Pub Date : 2015-02-27 eCollection Date: 2015-01-01 DOI:10.2174/1874104501509010001
Kamal Chaouachi
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引用次数: 0

摘要

背景:反吸烟研究人员重新审视了 "流行病 "的传统定义。400 年后,医生们会意识到,亚洲和非洲社会古老的日常文化习俗的一个方面实际上是一种 "全球'流行病'"。这需要进一步的调查,尤其是在考虑到烧烤的健康问题时:方法:在这里,最新的生物医学成果与人类学研究结果(即现实生活中的研究结果)辩证地对立起来,以突出全球混淆的程度:从 "流行病 "和 "流行率 "的新定义到 "尼古丁'上瘾'"的神话,以及与滤水烟管(WFTSPs)有关的其他主题:我们发现,在过去的十年中,许多出版物,尤其是关于滤水烟斗的综述、"元分析 "和 "系统综述",实际上助长了生物医学研究中有史以来最大的混淆。造成这种局面的一个主要原因是对现有文献绝对缺乏批判性分析,而且不加批判地使用引文(一篇存在严重缺陷的综述被引用多达 200 次)。另一个主要原因是将贝鲁特美利坚大学设计的有偏见的吸烟机器人视为理所当然,根据相同的 "协议",该机器人测得的有毒化学物质产量可能与其他机器人的产量相差数十倍。我们还发现,十多年来,还有两个主要的方法问题:结论:绝大多数 WFTSP 毒性研究都自愿或非自愿地测量了滥用方面,而不是使用本身。这与减少危害和公共卫生理论相矛盾。应鼓励而不是扼杀负面结果的发表。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Use & Misuse of Water-filtered Tobacco Smoking Pipes in the World. Consequences for Public Health, Research & Research Ethics.

Background: The traditional definition of an "epidemic" has been revisited by antismoking researchers. After 400 years, Doctors would have realized that one aspect of an ancient cultural daily practice of Asian and African societies was in fact a "global "epidemic"". This needed further investigation particularly if one keeps in his mind the health aspects surrounding barbecues.

Method: Here, up-to-date biomedical results are dialectically confronted with anthropological findings, hence in real life, in order to highlight the extent of the global confusion: from the new definition of an "epidemic" and "prevalence" to the myth of "nicotine "addiction"" and other themes in relation to water filtered tobacco smoking pipes (WFTSPs).

Results: We found that over the last decade, many publications, -particularly reviews, "meta-analyses" and "systematic reviews"- on (WFTSPs), have actually contributed to fuelling the greatest mix-up ever witnessed in biomedical research. One main reason for such a situation has been the absolute lack of critical analysis of the available literature and the uncritical use of citations (one seriously flawed review has been cited up to 200 times). Another main reason has been to take as granted a biased smoking robot designed at the US American of Beirut whose measured yields of toxic chemicals may differ dozens of times from others' based on the same "protocol". We also found that, for more than one decade, two other main methodological problems are: 1) the long-lived unwillingness to distinguish between use and misuse; 2) the consistent unethical rejection of biomedical negative results which, interestingly, are quantitatively and qualitatively much more instructive than the positive ones.

Conclusion: the great majority of WFTSP toxicity studies have actually measured, voluntarily or not, their misuse aspects, not the use in itself. This is in contradiction with both the harm reduction and public health doctrines. The publication of negative results should be encouraged instead of being stifled.

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来源期刊
Open Medicinal Chemistry Journal
Open Medicinal Chemistry Journal Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science
CiteScore
4.40
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0.00%
发文量
4
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