梗阻性黄疸患者胆道引流前后横波弥散斜率值的意义:一项单中心前瞻性观察队列研究。

IF 0.7 4区 医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Ultrasound Quarterly Pub Date : 2023-09-01 DOI:10.1097/RUQ.0000000000000644
Ryo Sugiura, Masaki Kuwatani, Mutsumi Nishida, Megumi Satoh, Kazumichi Kawakubo, Shin Kato, Koji Hirata, Masahito Nakajima, Hajime Hirata, Yunosuke Takishin, Naoya Sakamoto
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引用次数: 0

摘要

摘要:横波色散(SWD)斜率与组织黏度有关,已广泛应用于临床。然而,尚未对阻塞性黄疸进行SWD临床评价。我们的目的是评价梗阻性黄疸患者胆道引流前后SWD值的变化。本前瞻性观察队列研究评估了20例接受胆道引流的梗阻性黄疸患者。分别在第-5天和第0天(第0天)、第1天和第3天(第2天)、第6天和第8天(第7天)测量胆道引流前后的SWD和肝脏弹性值。第0天、第2天和第7天测量的SWD的平均±SD值分别为15.3±2.7、14.2±3.3和13.3±2.4 m/s/kHz。离散斜率值在第0天至第2天、第2天至第7天、第0天至第7天显著降低(P < 0.05)。肝弹性水平和血清肝胆酶也随着胆道引流后的时间显著下降。SWD与肝弹性值相关性较强(r = 0.91, P < 0.01)。综上所述,在胆道引流伴肝弹性后,SWD值随时间显著下降。
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Significance of Shear Wave Dispersion Slope Values Before Versus After Biliary Drainage in Patients With Obstructive Jaundice: A Single-Center Prospective Observational Cohort Study.

Abstract: The shear wave dispersion (SWD) slope has become available in the clinical practice and is related to tissue viscosity. However, clinical evaluation using SWD was not yet performed for obstructive jaundice. We aimed to evaluate the change of SWD values between before and after biliary drainage in patients with obstructive jaundice. This prospective observational cohort study evaluated 20 patients with obstructive jaundice who underwent biliary drainage. The SWD and liver elasticity values were measured before versus after biliary drainage, comparing between days -5 and 0 (day 0), days 1 and 3 (day 2), and days 6 and 8 (day 7). The mean ± SD values of SWD measured at day 0, day 2, and day 7 were 15.3 ± 2.7, 14.2 ± 3.3, and 13.3 ± 2.4 m/s/kHz, respectively. Dispersion slope values were decreased significantly from day 0 to day 2, from day 2 to day 7, and from day 0 to day 7 ( P < 0.05). Liver elasticity levels and serum hepatobiliary enzymes were additionally decreased significantly over time after biliary drainage. The correlations between SWD and liver elasticity values were strong ( r = 0.91, P < 0.01). In conclusion, t he SWD values decreased significantly over time after biliary drainage concomitant with liver elasticity.

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来源期刊
Ultrasound Quarterly
Ultrasound Quarterly RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
2.50
自引率
7.70%
发文量
105
审稿时长
>12 weeks
期刊介绍: Ultrasound Quarterly provides coverage of the newest, most sophisticated ultrasound techniques as well as in-depth analysis of important developments in this dynamic field. The journal publishes reviews of a wide variety of topics including trans-vaginal ultrasonography, detection of fetal anomalies, color Doppler flow imaging, pediatric ultrasonography, and breast sonography. Official Journal of the Society of Radiologists in Ultrasound
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