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Objective Analysis of Predictive Value of Ultrasound Quantitative Scoring System for Treatment Method Selection in Cesarean Scar Pregnancy. 客观分析超声定量评分系统对剖宫产瘢痕妊娠治疗方法选择的预测价值
IF 0.7 4区 医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-26 eCollection Date: 2024-09-01 DOI: 10.1097/RUQ.0000000000000690
Jieying Zhang, Yingying Liu, Hui Wan, Yue Lu, Yanli Xin, Jianwen Du, Hong Wang

Abstract: This study aimed to explore the feasibility of using the ultrasound quantitative scoring system to guide the selection of surgical methods for a cesarean scar ectopic pregnancy (CSEP). A retrospective analysis was conducted of the medical records of 117 cases of patients with a CSEP. All patients underwent transvaginal ultrasound examination before treatment, and the ultrasound results were compared with the results of surgical exploration. The treatment methods that were delivered for the 2 patient groups with CSEP were analyzed, and agreement between the predicted and actual treatment protocols was tested using the kappa consistency test. Residual myometrial thickness at the scar site was mainly concentrated above 3 mm in the low-risk group, with 70 cases accounting for 76.9%, while in the high-risk group, this was primarily in the range of 1-3 mm with 18 cases accounting for 69.2%. The grading of nourishing blood supply to the gestational sac showed that 96.7% of patients in the low-risk group had Grade I and Grade II blood flow, while 84.6% of the high-risk group had Grade I and Grade II blood flow; Grade II blood flow was predominant in the high-risk group. The majority of patients in both the low- and high-risk groups experienced intraoperative blood loss of ≤50 mL (93.9% vs 80.6%, respectively). The consistency test between the actual and predicted treatment methods yielded a kappa coefficient of 0.644, indicating consistency between the two. For patients with CSEP in the low-risk group (score <4), the ultrasound quantitative scoring system could provide individualized assessment and offer clinically valuable treatment protocols.

摘要:本研究旨在探讨使用超声定量评分系统指导剖宫产瘢痕异位妊娠(CSEP)手术方法选择的可行性。研究对 117 例 CSEP 患者的病历进行了回顾性分析。所有患者在治疗前均接受了经阴道超声检查,并将超声检查结果与手术探查结果进行了比较。分析了两组 CSEP 患者的治疗方法,并使用卡帕一致性检验法检验了预测治疗方案与实际治疗方案之间的一致性。低风险组瘢痕部位残留子宫肌厚度主要集中在3毫米以上,有70例,占76.9%;而高风险组主要集中在1-3毫米之间,有18例,占69.2%。孕囊营养血供分级显示,低危组 96.7%的患者有Ⅰ级和Ⅱ级血流,而高危组 84.6%的患者有Ⅰ级和Ⅱ级血流;高危组以Ⅱ级血流为主。低风险组和高风险组的大多数患者术中失血量均小于 50 毫升(分别为 93.9% 和 80.6%)。实际治疗方法和预测治疗方法之间的一致性检验得出的卡帕系数为 0.644,表明两者之间具有一致性。对于低风险组的 CSEP 患者(得分
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引用次数: 0
Role of Combining Grayscale Findings With Superb Microvascular Imaging and Shear Wave Elastography in Standardization and Management of NON-MASS Breast Lesions. 将灰度结果与超微血管成像和剪切波弹性成像相结合在非质量乳腺病变的标准化和管理中的作用。
IF 0.7 4区 医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-22 eCollection Date: 2024-09-01 DOI: 10.1097/RUQ.0000000000000689
Seda Aladag Kurt, Fusun Taskin, Yasemin Kayadibi, Tulin Ozturk, İbrahim Adaletli, Gul Esen Icten

Abstract: The non-mass breast lesions on ultrasound (US) are a group of challenging pathology. We aimed to standardize these grayscale findings and investigate the effectiveness of superb microvascular imaging (SMI) and shear wave elastography (SWE). A total of 195 lesions were evaluated by B-mode US, SWE, and SMI in the same session. A "NON-MASS model" was built on grayscale US to group the lesions only as areas and those with associated features: microcalcifications, architectural distortion, ductal changes, and microcysts. The mean stiffness parameters Emean, Eratio, and mean vascular index (VI) were recorded following consecutive measurements. Besides, the microvascularity was graded based on Adler's classification (grades 0 to 3). Lesions were divided into 3 groups: benign, category B3, and malignant. One hundred twelve (57.4%) lesions were benign, 23 (11.8%) were B3, and 60 were (30.8%) in the malignant category. Thirty-eight (19.5%) lesions were observed only as an area, whereas associated features were present in 157 lesions (80.5%). Distortion was the only associated feature predicting malignancy among the grayscale findings (P < 0.001). There was a significant difference between malignant and nonmalignant (benign and B3) groups in terms of Adler's grade, Emean, Eratio, and VI values (P < 0.001). Sensitivity, specificity, and accuracy increased when advanced imaging parameters were added to grayscale findings (P < 0.001). In the presence of microcalcifications, architectural distortion, high elasticity, and hypervascularity in the "NON-MASS" imaging model, the suspicion of malignancy increases. The non-mass findings and advanced imaging techniques have the potential to find greater coverage in the following versions of BI-RADS atlas.

摘要:超声(US)显示的非肿块性乳腺病变是一组具有挑战性的病理。我们的目的是将这些灰度检查结果标准化,并研究超微血管成像(SMI)和剪切波弹性成像(SWE)的有效性。我们在同一疗程中通过 B 型 US、SWE 和 SMI 对 195 个病灶进行了评估。在灰阶 US 上建立了一个 "NON-MASS 模型",仅将病变分为区域和具有相关特征的病变:微钙化、结构变形、导管变化和微囊。连续测量后记录平均硬度参数 Emean、Eratio 和平均血管指数(VI)。此外,还根据阿德勒分类法(0 至 3 级)对微血管进行了分级。病变分为三组:良性、B3 类和恶性。112个(57.4%)病灶为良性,23个(11.8%)为B3类,60个(30.8%)为恶性。有 38 个(19.5%)病灶仅观察到一个区域,而有 157 个病灶(80.5%)存在相关特征。在灰度结果中,变形是预测恶性的唯一相关特征(P < 0.001)。恶性组和非恶性组(良性和 B3)在 Adler 分级、Emean、Eratio 和 VI 值方面存在明显差异(P < 0.001)。在灰度结果中加入高级成像参数后,灵敏度、特异性和准确性均有所提高(P < 0.001)。在 "非肿块 "成像模型中,如果存在微钙化、结构变形、高弹性和高血管性,则对恶性肿瘤的怀疑会增加。非肿块检查结果和先进的成像技术有可能在后续版本的 BI-RADS 图谱中得到更广泛的应用。
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引用次数: 0
Nonvisualized Ovaries on Ultrasound: Correlation With Surgical Pathology. 超声检查中未显示的卵巢:与手术病理学的相关性
IF 0.7 4区 医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-22 eCollection Date: 2024-09-01 DOI: 10.1097/RUQ.0000000000000691
Ahmad Alhamshari, Hannah R Krigman, Cary L Siegel, Quing Zhu, Malak Itani

Abstract: The risk of malignancy in nonvisualized ovaries on pelvic ultrasound is presumed to be close to zero per imaging correlation; the goal of this manuscript is to define the risk of malignancy in nonvisualized ovaries on pelvic ultrasound as defined by surgical pathology. Records for patients with pelvic ultrasound and surgical pathology containing the word "ovary" or "ovaries" performed at our institution between 10/1/2015 and 9/30/2021 were reviewed. Data for ovarian visualization were extracted from the radiology report and correlated with surgical pathology results within each ovary. Eighty-seven ovaries in 71 patients out of 422 ovaries (20.6%) in 215 eligible patients were not visualized on ultrasound. Twenty ovaries were excluded because imaging showed large pelvic mass, and 19 ovaries were excluded because surgical pathology for the ovary of interest was not available. A total of 48 ovaries in 37 patients were nonvisualized and had available surgical pathology. Out of 48 nonvisualized ovaries, 31 were normal on surgical pathology and 17 had abnormalities, with 15 benign lesions (12 of which were ≤1 cm in size). Two ovaries in 1 patient contained malignant lesions; although the ovaries were not visualized on ultrasound, the scan demonstrated peritoneal carcinomatosis. In conclusion, a high proportion of ovaries (20.6%, 87/422) are not visualized on pelvic ultrasound, and surgical pathology reveals ovarian lesions in 35.4% (17/48) of nonvisualized ovaries on pelvic ultrasound, with the majority being subcentimeter benign lesions. In the absence of peritoneal carcinomatosis, nonvisualized ovaries had no malignant lesions.

摘要:根据影像学相关性推测,盆腔超声检查未见卵巢的恶性肿瘤风险接近于零;本手稿的目的是根据手术病理学定义盆腔超声检查未见卵巢的恶性肿瘤风险。本研究回顾了 2015 年 10 月 1 日至 2021 年 9 月 30 日期间在本院进行盆腔超声检查和手术病理检查且包含 "卵巢 "或 "卵巢 "字样的患者记录。从放射学报告中提取了卵巢可视化数据,并与每个卵巢内的手术病理结果进行了关联。在215名符合条件的患者的422个卵巢(20.6%)中,有71名患者的87个卵巢在超声检查中未被观察到。20个卵巢因成像显示盆腔肿块较大而被排除,19个卵巢因无法获得相关卵巢的手术病理结果而被排除。共有 37 名患者的 48 个卵巢未显影且有手术病理结果。在 48 个未显影的卵巢中,31 个手术病理结果正常,17 个异常,其中 15 个良性病变(其中 12 个大小≤1 厘米)。1 名患者的两个卵巢含有恶性病变;虽然超声波检查未发现卵巢,但扫描结果显示为腹膜癌。总之,盆腔超声检查未发现卵巢病变的比例很高(20.6%,87/422),而手术病理检查显示,盆腔超声检查未发现卵巢病变的患者中,有 35.4%(17/48)的患者存在卵巢病变,其中大多数为厘米以下的良性病变。在没有腹膜癌变的情况下,未见卵巢没有恶性病变。
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引用次数: 0
Reliability of a 2D-Panoramic Ultrasound System for the Determination of Muscle Volume in Older Hospitalized Patients. 二维全景超声系统测定老年住院患者肌肉体积的可靠性
IF 0.7 4区 医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-08 eCollection Date: 2024-09-01 DOI: 10.1097/RUQ.0000000000000688
Anne Sophie Boureau, Sylvain Anger, Christophe Cornu, Marie Mathieu, Gilles Berrut, Antoine Nordez

Abstract: Reliability of muscle thickness assessed in B-mode ultrasound has been confirmed in adults but remains a less direct assessment of muscle mass than muscle volume (MV). The aim of this prospective monocentric study was to assess the interday reliability of MV determined by the 2D-panoramic ultrasound in older hospitalized patients.Ten participants hospitalized in geriatric ward (mean age = 84) underwent 2 sessions of panoramic ultrasound scanning 1 week apart for MV assessment and DXA for leg lean mass (LLM) assessment when it was possible. The interday reliability of MV assessed using the intraclass correlation coefficient (ICC) was excellent, whatever was the muscle analyzed: ICC = 0.99 for tibialis anterior; ICC = 0.99 for vastus lateralis; ICC = 1 for rectus femoris. The pilot analysis of its association with leg lean mass revealed a good association between the vastus lateralis MV and LLM, but this needs to be confirmed on a larger number of participants (Pearson correlation coefficient = 0.91, P = 0.03).The 2D-panoramic ultrasound system for the determination of MV was reliable in older hospitalized patients with measurements performed on the patient's bed. MV seemed to be more correlated to LLM than muscle thickness. Future research will need to reduce the data processing time maybe with automation of data measurement.

摘要:B型超声波评估肌肉厚度的可靠性已在成人中得到证实,但与肌肉体积(MV)相比,B型超声波仍无法直接评估肌肉质量。这项前瞻性单中心研究的目的是评估老年住院患者通过二维全景超声波测定的肌肉体积的日间可靠性。使用类内相关系数(ICC)评估的肌肉重量的日间可靠性非常好,无论分析的是哪块肌肉:胫骨前肌的 ICC = 0.99;股外侧肌的 ICC = 0.99;股直肌的 ICC = 1。对其与腿部瘦体重的关联性进行的试验分析表明,阔肌MV与LLM之间存在良好的关联性,但这还需要在更多的参与者身上得到证实(皮尔逊相关系数=0.91,P=0.03)。与肌肉厚度相比,MV 与 LLM 的相关性似乎更高。未来的研究将需要缩短数据处理时间,或许可以实现数据测量的自动化。
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引用次数: 0
Pediatric Cranial Ultrasound Revisited: A Comprehensive Review. 重温小儿头颅超声:全面回顾。
IF 0.7 4区 医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-07-10 eCollection Date: 2024-09-01 DOI: 10.1097/RUQ.0000000000000684
Edward J Richer, Erica L Riedesel

Abstract: Cranial ultrasound (CUS) is an indispensable tool in the evaluation of intracranial pathology in premature and term neonates and older infants. Familiarity with standard cranial ultrasound techniques and parameters, normal anatomy, and commonly encountered abnormalities is crucial for providing appropriate care for these patients. This review provides a comprehensive overview of cranial ultrasound in clinical practice.

摘要:头颅超声(CUS)是评估早产儿、足月新生儿和较大婴儿颅内病变不可或缺的工具。熟悉标准的头颅超声技术和参数、正常解剖结构以及常见的异常情况对于为这些患者提供适当的护理至关重要。本综述全面概述了颅脑超声在临床实践中的应用。
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引用次数: 0
The Application Value of Using Semiquantitative and Quantitative Parameters in Multimodal Ultrasound to Distinguish Between Benign and Malignant BI-RADS 4 Lesions. 在多模态超声中使用半定量和定量参数区分良性和恶性 BI-RADS 4 病变的应用价值。
IF 0.7 4区 医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-07-05 eCollection Date: 2024-09-01 DOI: 10.1097/RUQ.0000000000000686
Xi Dai, Xiao-Yu Zhou, Piao-Fei Chen, Zhe-Li Gong, Zhi-Ping Wang, Di Wang

Abstract: This study aims to explore the value of real-time strain elastography (RTE) and contrast-enhanced ultrasonography (CEUS) in the diagnosis of breast BI-RADS 4 lesions. It collected 85 cases (totaling 85 lesions) diagnosed with breast BI-RADS 4 through routine ultrasound from October 2020 to December 2022 in Huangshan City People's Hospital. All lesions underwent RTE and CEUS examination before surgery, and the ImageJ software was used to measure the periphery of lesion images in the enhancement peak mode and grayscale mode to calculate the contrast-enhanced ultrasound area ratio. The diagnostic capabilities of single-modal and multimodal ultrasound examination for the malignancy of breast BI-RADS 4 lesions were compared using the receiver operating characteristic curve; the Spearman correlation analysis was adopted to evaluate the correlation between multimodal ultrasound and CEUS area ratio. As a result, among the 85 lesions, 51 were benign, and 34 were malignant. The areas under the curve (AUCs) of routine ultrasound (US), US + RTE, US + CEUS, and US + RTE + CEUS were 0.816, 0.928, 0.953, and 0.967, respectively, with the combined method showing a higher AUC than the single application. The AUC of the CEUS area ratio diagnosing breast lesions was 0.888. There was a strong positive correlation (r = 0.819, P < 0.001) between the diagnostic performance of US + RTE + CEUS and the CEUS area ratio. In conclusion, based on routine ultrasound, the combination of RTE and CEUS can further improve the differential diagnosis of benign and malignant lesions in breast BI-RADS 4.

摘要:本研究旨在探讨实时应变弹性成像(RTE)和对比增强超声成像(CEUS)在乳腺BI-RADS 4病变诊断中的应用价值。本研究收集了黄山市人民医院2020年10月至2022年12月通过常规超声诊断为乳腺BI-RADS 4的85例病例(共85个病灶)。所有病灶术前均进行了RTE和CEUS检查,采用ImageJ软件在增强峰值模式和灰度模式下测量病灶图像的周边,计算对比增强超声面积比。采用接收者操作特征曲线比较单模态和多模态超声检查对乳腺 BI-RADS 4 病变恶性程度的诊断能力;采用 Spearman 相关分析评价多模态超声与 CEUS 面积比的相关性。结果显示,在 85 个病灶中,51 个为良性,34 个为恶性。常规超声(US)、US + RTE、US + CEUS和US + RTE + CEUS的曲线下面积(AUC)分别为0.816、0.928、0.953和0.967,联合方法的AUC高于单一应用。CEUS 面积比诊断乳腺病变的 AUC 为 0.888,US + RTE + CEUS 的诊断性能与 CEUS 面积比之间存在很强的正相关性(r = 0.819,P < 0.001)。总之,在常规超声检查的基础上,RTE 和 CEUS 的联合应用可进一步提高乳腺 BI-RADS 4 良性和恶性病变的鉴别诊断。
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引用次数: 0
Characterizing Sentinel Lymph Node Status in Breast Cancer Patients Using a Deep-Learning Model Compared With Radiologists' Analysis of Grayscale Ultrasound and Lymphosonography. 利用深度学习模型描述乳腺癌患者前哨淋巴结状态与放射科医生对灰度超声波和淋巴造影的分析比较
IF 0.7 4区 医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-07-03 eCollection Date: 2024-09-01 DOI: 10.1097/RUQ.0000000000000683
Priscilla Machado, Aylin Tahmasebi, Samuel Fallon, Ji-Bin Liu, Basak E Dogan, Laurence Needleman, Melissa Lazar, Alliric I Willis, Kristin Brill, Susanna Nazarian, Adam Berger, Flemming Forsberg

Abstract: The objective of the study was to use a deep learning model to differentiate between benign and malignant sentinel lymph nodes (SLNs) in patients with breast cancer compared to radiologists' assessments.Seventy-nine women with breast cancer were enrolled and underwent lymphosonography and contrast-enhanced ultrasound (CEUS) examination after subcutaneous injection of ultrasound contrast agent around their tumor to identify SLNs. Google AutoML was used to develop image classification model. Grayscale and CEUS images acquired during the ultrasound examination were uploaded with a data distribution of 80% for training/20% for testing. The performance metric used was area under precision/recall curve (AuPRC). In addition, 3 radiologists assessed SLNs as normal or abnormal based on a clinical established classification. Two-hundred seventeen SLNs were divided in 2 for model development; model 1 included all SLNs and model 2 had an equal number of benign and malignant SLNs. Validation results model 1 AuPRC 0.84 (grayscale)/0.91 (CEUS) and model 2 AuPRC 0.91 (grayscale)/0.87 (CEUS). The comparison between artificial intelligence (AI) and readers' showed statistical significant differences between all models and ultrasound modes; model 1 grayscale AI versus readers, P = 0.047, and model 1 CEUS AI versus readers, P < 0.001. Model 2 r grayscale AI versus readers, P = 0.032, and model 2 CEUS AI versus readers, P = 0.041.The interreader agreement overall result showed κ values of 0.20 for grayscale and 0.17 for CEUS.In conclusion, AutoML showed improved diagnostic performance in balance volume datasets. Radiologist performance was not influenced by the dataset's distribution.

摘要:这项研究的目的是利用深度学习模型,与放射科医生的评估结果相比,区分乳腺癌患者前哨淋巴结(SLN)的良性和恶性。谷歌 AutoML 被用来开发图像分类模型。上传超声检查过程中获取的灰度和 CEUS 图像,数据分布为 80% 用于训练/20% 用于测试。使用的性能指标是精确度/调用曲线下面积(AuPRC)。此外,3 名放射科医生根据临床确定的分类方法评估 SLN 正常或异常。217 个 SLN 分成 2 个模型进行开发;模型 1 包括所有 SLN,模型 2 包括相同数量的良性和恶性 SLN。验证结果模型 1 AuPRC 0.84(灰度)/0.91(CEUS),模型 2 AuPRC 0.91(灰度)/0.87(CEUS)。人工智能(AI)与读者的比较显示,所有模型和超声模式之间都存在显著的统计学差异;模型 1 灰度 AI 与读者的比较,P = 0.047;模型 1 CEUS AI 与读者的比较,P < 0.001。总之,AutoML 在平衡容积数据集中显示出更高的诊断性能。总之,AutoML 提高了平衡容积数据集的诊断性能,放射医师的表现不受数据集分布的影响。
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引用次数: 0
Revisiting the Hepatorenal Index in the Quantification of Hepatic Steatosis: How it is done and the utility. 重新审视肝脏脂肪变性定量分析中的肝脏指数:方法和效用。
IF 0.7 4区 医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-06-18 eCollection Date: 2024-09-01 DOI: 10.1097/RUQ.0000000000000681
Kevin Duncan, Beth L Vealé

Methods: Twenty-three peer-reviewed articles on HRI measurements published between 2018 through 2023 were reviewed, and 11 were selected based on common subjects. The search terms included "hepatorenal index," "HRI," "HRI ultrasound," "hepatorenal ultrasound index," and "HRI ultrasound measurement."Three common subject areas were identified in the literature and synthesized down to 11 articles. The common subjects identified were HRI technique, HRI limitations, and HRI diagnostic accuracy. The matrix provided a quick overview of the general information in each piece, aiding in the paper's overall organization. Thirteen articles were rejected as not relevant or out of date. The research question leading this review was, "What does the literature say about the value of HRI in determining moderate to severe hepatic steatosis?"

Results: The literature revealed that HRI could be valuable in determining moderate to severe hepatic steatosis. HRI could not accurately determine normal or mild steatosis and has several limitations.

Conclusions: HRI is a more objective method for determining the degree of hepatic steatosis compared with traditional B-mode ultrasound scoring and does not require additional or specialized equipment. Many studies excluded patients with various liver diseases, which may not make HRI a practical tool for clinical usefulness. Further studies should be conducted with larger patient cohorts, a greater degree of hepatic steatosis, and determine specific standardized cutoff values.

方法:对2018年至2023年间发表的23篇有关HRI测量的同行评议文章进行了回顾,并根据共同主题筛选出11篇。检索词包括 "肝肾指数"、"HRI"、"HRI 超声"、"肝肾超声指数 "和 "HRI 超声测量"。在文献中确定了三个共同主题领域,并综合归纳为 11 篇文章。确定的共同主题包括 HRI 技术、HRI 限制和 HRI 诊断准确性。矩阵提供了每篇文章中一般信息的快速概览,有助于论文的整体组织。有 13 篇文章因不相关或过时而被剔除。本综述的研究问题是:"关于 HRI 在确定中度至重度肝脂肪变性方面的价值,文献是怎么说的?文献显示,HRI 对确定中度至重度肝脂肪变性很有价值。HRI 无法准确判断正常或轻度脂肪变性,并且存在一些局限性:与传统的 B 型超声评分相比,HRI 是确定肝脏脂肪变性程度的一种更客观的方法,而且不需要额外或专门的设备。许多研究排除了患有各种肝病的患者,这可能使 HRI 无法成为临床实用的工具。应针对更大的患者群体、更严重的肝脏脂肪变性进行进一步研究,并确定具体的标准化临界值。
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引用次数: 0
A Nomogram Based on Conventional Ultrasound Radiomics for Differentiating Between Radial Scar and Invasive Ductal Carcinoma of the Breast. 基于常规超声放射组学的乳腺径向疤痕和浸润性乳腺导管癌鉴别提名图。
IF 0.7 4区 医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-06-18 eCollection Date: 2024-09-01 DOI: 10.1097/RUQ.0000000000000685
Huan-Zhong Su, Long-Cheng Hong, Yi-Ming Su, Xiao-Shuang Chen, Zuo-Bing Zhang, Xiao-Dong Zhang

Abstract: We aimed to develop and validate a nomogram based on conventional ultrasound (CUS) radiomics model to differentiate radial scar (RS) from invasive ductal carcinoma (IDC) of the breast. In total, 208 patients with histopathologically diagnosed RS or IDC of the breast were enrolled. They were randomly divided in a 7:3 ratio into a training cohort (n = 145) and a validation cohort (n = 63). Overall, 1316 radiomics features were extracted from CUS images. Then a radiomics score was constructed by filtering unstable features and using the maximum relevance minimum redundancy algorithm and the least absolute shrinkage and selection operator logistic regression algorithm. Two models were developed using data from the training cohort: one using clinical and CUS characteristics (Clin + CUS model) and one using clinical information, CUS characteristics, and the radiomics score (radiomics model). The usefulness of nomogram was assessed based on their differentiating ability and clinical utility. Nine features from CUS images were used to build the radiomics score. The radiomics nomogram showed a favorable predictive value for differentiating RS from IDC, with areas under the curve of 0.953 and 0.922 for the training and validation cohorts, respectively. Decision curve analysis indicated that this model outperformed the Clin + CUS model and the radiomics score in terms of clinical usefulness. The results of this study may provide a novel method for noninvasively distinguish RS from IDC.

摘要:我们旨在开发并验证一种基于常规超声(CUS)放射组学模型的提名图,用于区分乳腺放射状瘢痕(RS)和浸润性导管癌(IDC)。研究共招募了 208 名经组织病理学诊断为乳腺放射瘢痕(RS)或乳腺浸润性导管癌(IDC)的患者。他们按 7:3 的比例被随机分为训练组(145 人)和验证组(63 人)。总共从 CUS 图像中提取了 1316 个放射组学特征。然后,通过过滤不稳定特征,并使用最大相关性最小冗余算法和最小绝对收缩与选择算子逻辑回归算法,构建了放射组学评分。利用训练队列中的数据建立了两个模型:一个使用临床和 CUS 特征(临床 + CUS 模型),另一个使用临床信息、CUS 特征和放射组学评分(放射组学模型)。根据提名图的区分能力和临床实用性对其有用性进行了评估。CUS 图像中的九个特征被用来建立放射组学评分。放射组学提名图在区分 RS 和 IDC 方面显示出良好的预测价值,训练组和验证组的曲线下面积分别为 0.953 和 0.922。决策曲线分析表明,该模型的临床实用性优于 Clin + CUS 模型和放射组学评分。这项研究的结果可能为无创区分 RS 和 IDC 提供了一种新方法。
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引用次数: 0
Arrival-Time Parametric Imaging in Contrast-Enhanced Ultrasound for Diagnosing Fibrosis in Primary Biliary Cholangitis: Erratum. 对比增强超声中的到达时间参数成像用于诊断原发性胆道胆管炎的纤维化:勘误。
IF 0.7 4区 医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-06-18 eCollection Date: 2024-09-01 DOI: 10.1097/RUQ.0000000000000682
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引用次数: 0
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Ultrasound Quarterly
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