【切除尿路移行细胞癌单发肺转移可延长部分患者的生存期】。

IF 0.5 4区 医学 Q4 SURGERY Zentralblatt fur Chirurgie Pub Date : 2025-02-01 Epub Date: 2023-09-05 DOI:10.1055/a-2148-1207
Benjamin Ehle, Mohamed Hassan, Uyen-Thao Le, Bernward Passlick, Konstantinos Grapatsas
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引用次数: 0

摘要

关于肺转移切除术治疗尿路移行细胞癌(TCC)的研究仅有少数发表。在这项研究中,我们根据本中心20年的经验,研究了与尿路TCC肺转移切除术相关的长期预后和预后生存因素。2000年至2020年间,18例患者(14例男性,4例女性)接受了肺转移切除术。回顾性分析临床、人口学和手术资料。原发肿瘤治疗和肺转移切除术之间的无病间隔为1至48个月。生存率分析采用Kaplan-Meier法和log-rank检验。3年和5年生存率分别为84.7%和52.9%。孤立转移灶的切除是生存率的积极和独立因素(p = 0.04)。尿路TCC肺转移切除术与良好的预后相关,单独转移与长期生存相关。手术切除孤立性肺转移和尿路TCC肺部复发的重复肺转移切除术在选定的患者中是可行的。
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[Resection of Solitary Lung Metastasis of Urinary Tract Transitional Cell Cancer Can Prolong Survival in Selected Patients].

There are only a few small published studies on pulmonary metastasectomy for urinary tract transitional cell carcinoma (TCC). In this study, we examined the long-term outcome and the prognostic survival factors associated with pulmonary metastasectomy of urinary tract TCC, as based on our centre's 20-year experience. Between 2000 and 2020, curative pulmonary metastasectomy was performed in 18 patients (14 males and 4 females). Clinical, demographical and surgical data were retrospectively analysed. The disease-free interval between treatment of the primary tumour and pulmonary metastasectomy ranged from one to 48 months. Survival analysis was conducted with the Kaplan-Meier method and log-rank test. The 3- and 5-year survival rates were 84.7% and 52.9%, respectively. Resection of solitary metastases was a positive and independent factor for survival (p = 0.04). Pulmonary metastasectomy of urinary tract TCC is associated with a favourable outcome and solitary metastasis is associated with long-term survival. Surgical resection of solitary pulmonary metastasis and repeated lung metastasectomy by pulmonary recurrence from a urinary tract TCC is feasible in selected patients.

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来源期刊
CiteScore
1.00
自引率
14.30%
发文量
116
审稿时长
6-12 weeks
期刊介绍: Konzentriertes Fachwissen aus Forschung und Praxis Das Zentralblatt für Chirurgie – alle Neuigkeiten aus der Allgemeinen, Viszeral-, Thorax- und Gefäßchirurgie.
期刊最新文献
[Correction: Staging and Diagnostics of Rectal Cancer]. [Resection of Solitary Lung Metastasis of Urinary Tract Transitional Cell Cancer Can Prolong Survival in Selected Patients]. [Scientific Activity in German Thoracic Surgery, as Measured in Publication Output]. Patients with Pulmonary Artery Reconstruction or Double Sleeve Resection Show Inferior Survival than Patients with Bronchial Sleeve Resection for Non-small Cell Lung Cancer. [Robotic Central Pancreatectomy].
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