眼药水在皮肤科的应用,文献综述。

IF 2.9 4区 医学 Q2 DERMATOLOGY Journal of Dermatological Treatment Pub Date : 2022-09-01 DOI:10.1080/09546634.2022.2079598
Sameh Magdy Sarsik, Heba Saed El-Amawy
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引用次数: 2

摘要

背景:由于药物通过皮肤和眼睛组织的吸收似乎相似,当局部治疗无法获得或负担不起时,市售眼药水可用于治疗皮肤病。本综述强调了fda批准的各种眼药水在皮肤科临床实践中的局部治疗和标签外应用。方法:全面的PubMed和Google Scholar图书馆搜索,使用各种关键词组合(滴眼液,眼液,结膜安装,皮肤疾病,局部,局部,-受体阻滞剂,前列腺素,环孢素,阿克拉尼定,阿托品,羟甲唑啉)。结果和结论:根据所回顾的研究结果,替马洛尔被强烈推荐用于婴儿血管瘤和其他血管性皮肤疾病,如血管瘤、卡波西肉瘤、痤疮、红斑痤疮和伤口愈合。比马前列素是一种药物,可用于治疗任何类型的毛少症,以及轻度局限性斑秃和白皮病。羟美唑啉是治疗面部红斑的理想药物。我们推荐阿克络定治疗轻度上睑下垂引起的肉毒杆菌神经毒素。我们不推荐阿托品治疗多汗症,尽管它可以帮助治疗由注射器瘤引起的囊液水肿和瘙痒。妥布霉素需要在随机对照试验中进行测试,然后才能证实它是治疗绿指甲综合征的一种可行的全身治疗方案。
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Uses of eye drops in dermatology, literature review.

Background: Since medication absorption through the skin and eye tissue seems similar, commercially available eye-drops could be used to treat skin diseases when topical therapies are unavailable or unaffordable. The FDA-approved and off-label applications of various eye drops used as topical treatments in dermatological clinical practice were highlighted in this review.Methodology: A thorough PubMed and Google Scholar library search using various combinations of the keywords (Eye drop, ocular solution, conjunctival installation, and skin diseases, topical, local, beta-blockers, prostaglandin, cyclosporin, apraclonidine, atropine, oxymetazoline).Results and conclusions: Based on the findings of the studies reviewed, timolol is highly recommended for infantile hemangioma and other vascular skin conditions such as angiomas, Kaposi sarcoma, acne, rosacea, and wound healing. Bimatoprost is a drug that can be used to treat hypotrichosis of any kind, as well as mild localized alopecia areata and leukoderma. Oxymetazoline ispromising for treating facial erythema. We recommend apraclonidine for mild upper eyelid ptosis induced botulinum neurotoxin. We don't recommend atropine for hyperhidrosis, although it can help with hydrocystomas and pruritis produced by syringomas. Tobramycin will need to be tested in RCTs before it can be confirmed as a viable alternative to systemic treatments for treating green nail syndrome.

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来源期刊
CiteScore
6.50
自引率
0.00%
发文量
145
审稿时长
6-12 weeks
期刊介绍: The Journal of Dermatological Treatment covers all aspects of the treatment of skin disease, including the use of topical and systematically administered drugs and other forms of therapy. The Journal of Dermatological Treatment is positioned to give dermatologists cutting edge information on new treatments in all areas of dermatology. It also publishes valuable clinical reviews and theoretical papers on dermatological treatments.
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