脊髓高级结构磁共振成像技术及其临床应用

IF 1.5 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Seminars in Ultrasound Ct and Mri Pub Date : 2023-10-01 DOI:10.1053/j.sult.2023.03.016
Lucas de M.T. Branco , Thiago J.R. Rezende , Fabiano Reis , Marcondes C. França Jr
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引用次数: 0

摘要

长期以来,技术障碍阻碍了高分辨率图像的获取和脊髓(SC)MRI可靠处理协议的开发。幸运的是,由于硬件和软件的改进,这种情况在过去5-10年中发生了变化。如今,凭借先进的方案,SC MRI被认为是几种遗传性和获得性神经疾病的有用工具,不仅用于诊断方法,还用于病理生理学研究,并作为疾病监测和临床试验的生物标志物。在这篇综述中,我们介绍了用于宏观和微观结构评估的高级SC MRI序列、有用的半自动和自动处理工具以及在遗传性小脑共济失调、遗传性痉挛性截瘫、运动神经元疾病和多发性硬化症等几种神经疾病中的临床应用。
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Advanced Structural Magnetic Resonance Imaging of the Spinal Cord: Technical Aspects and Clinical Use

For a long time, technical obstacles have hampered the acquisition of high-resolution images and the development of reliable processing protocols for spinal cord (SC) MRI. Fortunately, this scenario has changed in the past 5-10 years, due to hardware and software improvements. Nowadays, with advanced protocols, SC MRI is considered a useful tool for several inherited and acquired neurologic diseases, not only for diagnosis approach but also for pathophysiological unraveling and as a biomarker for disease monitoring and clinical trials. In this review, we address advanced SC MRI sequences for macrostructural and microstructural evaluation, useful semiautomatic and automatic processing tools and clinical applications on several neurologic conditions such as hereditary cerebellar ataxia, hereditary spastic paraplegia, motor neuron diseases and multiple sclerosis.

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来源期刊
CiteScore
2.60
自引率
0.00%
发文量
49
审稿时长
6-12 weeks
期刊介绍: Seminars in Ultrasound, CT and MRI is directed to all physicians involved in the performance and interpretation of ultrasound, computed tomography, and magnetic resonance imaging procedures. It is a timely source for the publication of new concepts and research findings directly applicable to day-to-day clinical practice. The articles describe the performance of various procedures together with the authors'' approach to problems of interpretation.
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