Aswathy Rajendra Kurup , Jeff Wigdahl , Jeremy Benson , Manel Martínez-Ramón , Peter Solíz , Vinayak Joshi
{"title":"使用迁移学习和多摄像头视网膜图像自动检测疟疾视网膜病变","authors":"Aswathy Rajendra Kurup , Jeff Wigdahl , Jeremy Benson , Manel Martínez-Ramón , Peter Solíz , Vinayak Joshi","doi":"10.1016/j.bbe.2022.12.003","DOIUrl":null,"url":null,"abstract":"<div><p><span><span>Cerebral malaria (CM) is a fatal syndrome found commonly in children less than 5 years old in Sub-saharan Africa and Asia. The retinal signs associated with CM are known as malarial retinopathy (MR), and they include highly specific retinal lesions such as whitening and hemorrhages. Detecting these lesions allows the detection of CM with high specificity. Up to 23% of CM, patients are over-diagnosed due to the presence of clinical symptoms also related to </span>pneumonia, meningitis, or others. Therefore, patients go untreated for these pathologies, resulting in death or neurological disability. It is essential to have a low-cost and high-specificity diagnostic technique for CM detection, for which We developed a method based on </span>transfer learning<span> (TL). Models pre-trained with TL select the good quality retinal images, which are fed into another TL model to detect CM. This approach shows a 96% specificity with low-cost retinal cameras.</span></p></div>","PeriodicalId":55381,"journal":{"name":"Biocybernetics and Biomedical Engineering","volume":null,"pages":null},"PeriodicalIF":5.3000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851283/pdf/","citationCount":"1","resultStr":"{\"title\":\"Automated malarial retinopathy detection using transfer learning and multi-camera retinal images\",\"authors\":\"Aswathy Rajendra Kurup , Jeff Wigdahl , Jeremy Benson , Manel Martínez-Ramón , Peter Solíz , Vinayak Joshi\",\"doi\":\"10.1016/j.bbe.2022.12.003\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p><span><span>Cerebral malaria (CM) is a fatal syndrome found commonly in children less than 5 years old in Sub-saharan Africa and Asia. The retinal signs associated with CM are known as malarial retinopathy (MR), and they include highly specific retinal lesions such as whitening and hemorrhages. Detecting these lesions allows the detection of CM with high specificity. Up to 23% of CM, patients are over-diagnosed due to the presence of clinical symptoms also related to </span>pneumonia, meningitis, or others. Therefore, patients go untreated for these pathologies, resulting in death or neurological disability. It is essential to have a low-cost and high-specificity diagnostic technique for CM detection, for which We developed a method based on </span>transfer learning<span> (TL). Models pre-trained with TL select the good quality retinal images, which are fed into another TL model to detect CM. This approach shows a 96% specificity with low-cost retinal cameras.</span></p></div>\",\"PeriodicalId\":55381,\"journal\":{\"name\":\"Biocybernetics and Biomedical Engineering\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":5.3000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851283/pdf/\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biocybernetics and Biomedical Engineering\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0208521622001140\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ENGINEERING, BIOMEDICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biocybernetics and Biomedical Engineering","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0208521622001140","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
Automated malarial retinopathy detection using transfer learning and multi-camera retinal images
Cerebral malaria (CM) is a fatal syndrome found commonly in children less than 5 years old in Sub-saharan Africa and Asia. The retinal signs associated with CM are known as malarial retinopathy (MR), and they include highly specific retinal lesions such as whitening and hemorrhages. Detecting these lesions allows the detection of CM with high specificity. Up to 23% of CM, patients are over-diagnosed due to the presence of clinical symptoms also related to pneumonia, meningitis, or others. Therefore, patients go untreated for these pathologies, resulting in death or neurological disability. It is essential to have a low-cost and high-specificity diagnostic technique for CM detection, for which We developed a method based on transfer learning (TL). Models pre-trained with TL select the good quality retinal images, which are fed into another TL model to detect CM. This approach shows a 96% specificity with low-cost retinal cameras.
期刊介绍:
Biocybernetics and Biomedical Engineering is a quarterly journal, founded in 1981, devoted to publishing the results of original, innovative and creative research investigations in the field of Biocybernetics and biomedical engineering, which bridges mathematical, physical, chemical and engineering methods and technology to analyse physiological processes in living organisms as well as to develop methods, devices and systems used in biology and medicine, mainly in medical diagnosis, monitoring systems and therapy. The Journal''s mission is to advance scientific discovery into new or improved standards of care, and promotion a wide-ranging exchange between science and its application to humans.