体重调整型造影剂,缩短了冠状动脉计算机断层扫描血管造影的注射时间,从而提高了图像质量。

IF 2 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Journal of Thoracic Imaging Pub Date : 2024-05-01 Epub Date: 2023-01-23 DOI:10.1097/RTI.0000000000000696
Liang Jin, Kun Wang, Xiaodong Wang, Cheng Li, Yingli Sun, Pan Gao, Yi Xiao, Ming Li
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引用次数: 0

摘要

目的:在步进式冠状动脉计算机断层扫描 (CCTA) 中,不建议缩短注射持续时间。我们旨在评估使用体重调整后的碘化造影剂(ICM)进行不同注射持续时间的 CCTA 的图像质量,以制定优化的 ICM 给药方案,从而在步射 CCTA 中获得令人信服的图像质量:共招募了 200 名连续的疑似冠状动脉疾病(CAD)患者,分为 A 组(N=50,350 mgI/mL,体重×0.8 mL/kg,注射持续时间为 13 秒)、B 组(N=50,350 mgI/mL,体重×0.9 mL/kg,注射时间 13 秒)、C 组(N=50,350 mgI/mL,体重×0.8 mL/kg,注射时间 12 秒)和 D 组(N=50,320 mgI/mL,体重×0.8 mL/kg,注射时间 13 秒)。对各组的患者特征、ICM 给药方案、计算机断层扫描(CT)定量值测量和定性图像评分进行了分析和比较:结果:A 组和 D 组的 ICM 容量、生理盐水容量、注射流速、总碘量和碘注射率在各组中最低。各组冠状动脉 CT 值均大于 300 HU。所有观察者的平均得分均超过 3 分。在 A 组中,CT 值与碘注射率呈显著正相关(r=0.226,PConclusions:体重×0.8 毫升/千克,注射时间为 13 秒,是提高图像质量的分步拍摄 CCTA 的综合选择,首选碘浓度为 350 毫克/毫升。
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Bodyweight-adjusted Contrast Media With Shortened Injection Duration for Step-and-Shoot Coronary Computed Tomography Angiography to Acquire Improved Image Quality.

Purpose: Shortened injection durations are not recommended in step-and-shoot coronary computed tomography angiography (CCTA). We aimed to evaluate the image quality of CCTA performed using bodyweight-adjusted iodinated contrast media (ICM) with different injection durations to generate an optimized ICM administration protocol to acquire convincible image quality in step-and-shoot CCTA.

Materials and methods: A total of 200 consecutive patients with suspected coronary artery disease (CAD) were enrolled in group A (N=50, 350 mgI/mL, bodyweight×0.8 mL/kg with a 13-s injection duration), group B (N=50, 350 mgI/mL, bodyweight×0.9 mL/kg with a 13-s injection duration), group C (N=50, 350 mgI/mL, bodyweight×0.8 mL/kg with a 12-s injection duration), and group D (N=50, 320 mgI/mL, bodyweight×0.8 mL/kg with a 13-s injection duration). Patient characteristics, ICM administration protocols, quantitative computed tomography (CT) value measurements, and qualitative image scores were analyzed and compared among the groups.

Results: Groups A and D achieved the lowest ICM volume, saline volume, injection flow rate, and total iodine and iodine injection rates among the groups. All the CT values of the coronary arteries in all groups were >300 HU. All the observers' average scores exceeded three points. In group A, the CT values showed significant positive correlation with the iodine injection rate ( r =0.226, P <0.001), whereas the signal-to-noise ratio ( r =-0.004, P =0.927) and contrast-to-noise ratio ( r =-0.006, P =0.893) values were not.

Conclusions: Bodyweight×0.8 mL/kg with a 13-second injection duration is a comprehensive option for step-and-shoot CCTA with improved image quality, and a 350 mgI/mL iodine concentration is preferred.

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来源期刊
Journal of Thoracic Imaging
Journal of Thoracic Imaging 医学-核医学
CiteScore
7.10
自引率
9.10%
发文量
87
审稿时长
6-12 weeks
期刊介绍: Journal of Thoracic Imaging (JTI) provides authoritative information on all aspects of the use of imaging techniques in the diagnosis of cardiac and pulmonary diseases. Original articles and analytical reviews published in this timely journal provide the very latest thinking of leading experts concerning the use of chest radiography, computed tomography, magnetic resonance imaging, positron emission tomography, ultrasound, and all other promising imaging techniques in cardiopulmonary radiology. Official Journal of the Society of Thoracic Radiology: Japanese Society of Thoracic Radiology Korean Society of Thoracic Radiology European Society of Thoracic Imaging.
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