胶质母细胞瘤经硬膜颅底浸润一例报告及文献复习。

IF 0.4 Q4 OTORHINOLARYNGOLOGY Case Reports in Otolaryngology Pub Date : 2023-01-01 DOI:10.1155/2023/4727288
Michael Thrull, Khaled Atasi, Lennart-Maximilian Boese, Mahmut Cakar, Ullrich Heller, Nils Jansen, Leoni-Christine Menzel, Hassan Omaimen, Katharina Theis, Damir Karacic, Diyan Dimov, Roland Coras, Randolf Klingebiel
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引用次数: 0

摘要

我们报告罕见的颞骨多形性胶质母细胞瘤(GBM)表现为肿瘤经硬膜延伸到邻近的乳突细胞。由于硬脑膜为轴内肿瘤提供了屏障,GBM很少渗透到颅底,即使它是一种有扩散倾向的高级星形细胞瘤。然而,已经确定了gbm诱导的颅骨侵犯的一些机制,使得这种实体非常罕见,但在其他不明确的脑内肿瘤延伸到颅底的病例中仍然是相关的鉴别诊断。此外,影像标记可能有助于区分颞骨轴外和轴内肿瘤浸润。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Transdural Skull Base Infiltration by Glioblastoma: Case Report and Review of the Literature.

We report the rare occurrence of a temporal glioblastoma multiforme (GBM) showing transdural tumor extension into adjacent mastoid cells. As the dura mater provides a barrier to intraaxial tumors, GBM seldom penetrates into the skull base, even though it is a high-grade astrocytoma with a tendency to spread. Yet, some mechanisms of GBM-induced skull invasion have been identified, making this entity a very rare but nonetheless relevant differential diagnosis in otherwise ambiguous cases of an intracerebral tumor extending into the skull base. In addition, imaging markers that may assist in distinguishing extra- from intraaxial tumor infiltration of the temporal bone are described.

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来源期刊
Case Reports in Otolaryngology
Case Reports in Otolaryngology OTORHINOLARYNGOLOGY-
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发文量
20
审稿时长
13 weeks
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