基于轻量级深度神经网络的乳腺癌组织图像分类检测。

H S Laxmisagar, M C Hanumantharaju
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引用次数: 2

摘要

许多研究人员开发了计算机辅助诊断(CAD)方法,利用组织病理学显微图像诊断乳腺癌。这些技术有助于提高苏木精和伊红染色图像活检诊断的准确性。另一方面,大多数CAD系统通常依赖于效率低下且耗时的手动特征提取方法。利用卷积层的深度学习(DL)模型,我们提出了一种提取乳腺癌分类中最有用的图像信息的方法。苏木精和伊红染色的乳腺活检图像可分为四组:良性病变、正常组织、原位癌和浸润性癌。为了正确分类不同类型的乳腺癌,对组织病理图像进行准确分类是很重要的。采用MobileNet体系结构模型,以较低的资源利用率获得较高的精度。该模型快速、廉价、安全,适用于早期乳腺癌的检测。这种轻量级的深度神经网络可以使用现场可编程门阵列来加速检测乳腺癌。DL已被用于成功地对乳腺癌进行分类。该模型使用分类交叉熵来学习给正确的类一个高概率,给其他类一个低概率。它被用于卷积神经网络(CNN)在聚类阶段之后的分类阶段,从而提高了所提系统的性能。为了测量训练和验证的准确性,在Google Colab上使用2496个CUDA核、12gb GDDR5 VRAM和12.6 GB RAM的强大GPU对模型进行了280次epoch的训练。我们的研究结果表明,与其他最先进的方法相比,采用卡方检验的深度CNN将乳腺癌组织病理学图像分类的准确率提高了11%以上。
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Detection of Breast Cancer with Lightweight Deep Neural Networks for Histology Image Classification.

Many researchers have developed computer-assisted diagnostic (CAD) methods to diagnose breast cancer using histopathology microscopic images. These techniques help to improve the accuracy of biopsy diagnosis with hematoxylin and eosin-stained images. On the other hand, most CAD systems usually rely on inefficient and time-consuming manual feature extraction methods. Using a deep learning (DL) model with convolutional layers, we present a method to extract the most useful pictorial information for breast cancer classification. Breast biopsy images stained with hematoxylin and eosin can be categorized into four groups namely benign lesions, normal tissue, carcinoma in situ, and invasive carcinoma. To correctly classify different types of breast cancer, it is important to classify histopathological images accurately. The MobileNet architecture model is used to obtain high accuracy with less resource utilization. The proposed model is fast, inexpensive, and safe due to which it is suitable for the detection of breast cancer at an early stage. This lightweight deep neural network can be accelerated using field-programmable gate arrays for the detection of breast cancer. DL has been implemented to successfully classify breast cancer. The model uses categorical cross-entropy to learn to give the correct class a high probability and other classes a low probability. It is used in the classification stage of the convolutional neural network (CNN) after the clustering stage, thereby improving the performance of the proposed system. To measure training and validation accuracy, the model was trained on Google Colab for 280 epochs with a powerful GPU with 2496 CUDA cores, 12 GB GDDR5 VRAM, and 12.6 GB RAM. Our results demonstrate that deep CNN with a chi-square test has improved the accuracy of histopathological image classification of breast cancer by greater than 11% compared with other state-of-the-art methods.

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来源期刊
Critical Reviews in Biomedical Engineering
Critical Reviews in Biomedical Engineering Engineering-Biomedical Engineering
CiteScore
1.80
自引率
0.00%
发文量
25
期刊介绍: Biomedical engineering has been characterized as the application of concepts drawn from engineering, computing, communications, mathematics, and the physical sciences to scientific and applied problems in the field of medicine and biology. Concepts and methodologies in biomedical engineering extend throughout the medical and biological sciences. This journal attempts to critically review a wide range of research and applied activities in the field. More often than not, topics chosen for inclusion are concerned with research and practice issues of current interest. Experts writing each review bring together current knowledge and historical information that has led to the current state-of-the-art.
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