评估斯蒂克兰医院修订后的临床研究所酒精使用戒断量表。

IF 1 4区 医学 Q4 PSYCHIATRY South African Journal of Psychiatry Pub Date : 2023-01-01 DOI:10.4102/sajpsychiatry.v29i0.1915
Creeshen P Muddapah, Lize Weich
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引用次数: 0

摘要

背景:酒精使用障碍(AUD)是南非(SA)的一个主要公共卫生问题。慢性酒精使用者突然停止或减少酒精摄入可导致戒断症状。苯二氮卓类药物是一种治疗选择,但由于其高度成瘾性,对于有终生药物滥用史的患者需要谨慎使用。使用修订的临床研究所酒精戒断量表(CIWA-Ar),在酒精戒断期间症状引发的苯二氮卓类药物处方与提高安全性和减少苯二氮卓类药物使用有关。目的:探讨酒精解毒过程中CIWA-Ar的实施是否影响苯二氮卓类药物的使用剂量和戒断相关结局。地点:斯蒂克兰精神病院酒精康复科。方法:对135例入院患者进行为期六个月的回顾性队列研究,比较两组:实施CIWA-Ar之前(2015年)和之后(2017年)。结果:研究注意到两组在社会人口学和酒精相关变量方面没有差异,两组都没有记录的并发症。2017年组需要苯二氮卓类药物的患者比例较低(33.8%对51.4%,p = 0.04),戒酒期间苯二氮卓类药物的中位总用量较低(0 mg对5 mg, p = 0.01)。结论:CIWA-Ar评定量表可有效替代原处方苯二氮卓类药物,并可减少酒精戒断期间苯二氮卓类药物的总剂量。贡献:在低风险AUD患者的SA治疗环境中,在停药期间使用症状触发方案,如CIWA-Ar评定量表,可以安全地实施。
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Assessing the revised Clinical Institute Withdrawal for Alcohol Scale use at Stikland Hospital.

Background: Alcohol use disorder (AUD) is a major public health concern in South Africa (SA). Abrupt cessation or reduction of alcohol intake in chronic users can result in withdrawal symptoms. Benzodiazepines are the treatment of choice but need to be used cautiously in patients with a lifetime history of substance abuse given their highly addictive potential. Symptom-triggered prescription of benzodiazepines during alcohol withdrawal using the Revised Clinical Institute Withdrawal for Alcohol Scale (CIWA-Ar) has been associated with improved safety and reduced benzodiazepines use.

Aim: To investigate if implementation of the CIWA-Ar during alcohol detoxification impacted the dose of benzodiazepines used and withdrawal-related outcomes.

Setting: Alcohol rehabilitation unit (ARU) at Stikland Psychiatric Hospital.

Methods: A retrospective cohort study of 135 admissions over a six-month period comparing two groups: before (2015) and after (2017) the implementation of the CIWA-Ar.

Results: The study noted no differences in sociodemographic and alcohol-associated variables between the two groups, and there were no recorded complications in either group. The 2017 group had a lower percentage of patients that required benzodiazepines (33.8% vs. 51.4%, p = 0.04) and a lower median total amount of benzodiazepines used during alcohol withdrawal (0 mg vs. 5 mg, p = 0.01).

Conclusions: The CIWA-Ar rating scale was an effective alternative to prescribing benzodiazepines pro re nata and decreased the total dose of benzodiazepines used during alcohol withdrawal.

Contribution: The use of a symptom triggered regime, like the CIWA-Ar rating scale, during withdrawal can be implemented safely in a SA treatment setting for patients with low-risk AUD.

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来源期刊
CiteScore
1.60
自引率
10.00%
发文量
56
审稿时长
>12 weeks
期刊介绍: The journal is the leading psychiatric journal of Africa. It provides open-access scholarly reading for psychiatrists, clinical psychologists and all with an interest in mental health. It carries empirical and conceptual research articles, reviews, editorials, and scientific letters related to psychiatry. It publishes work from various places in the world, and makes special provision for the interests of Africa. It seeks to serve its readership and researchers with the most topical content in psychiatry for clinical practice and academic pursuits, including work in the subspecialty areas of psychiatry.
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