重建主动脉瓣幕后的手术效果

IF 2.6 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Seminars in Thoracic and Cardiovascular Surgery Pub Date : 2024-06-01 DOI:10.1053/j.semtcvs.2022.11.008
Markian Bojko MD, MPH , Korri S. Hershenhouse MD , Ramsey S. Elsayed MD , Brittany Abt MD , Robbin G. Cohen MD. MMM , Raymond Lee MD , Michael E. Bowdish MD, MS , Vaughn A. Starnes MD
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引用次数: 0

摘要

同时患有主动脉瓣和二尖瓣疾病并累及主动脉-二尖瓣瓣膜时,需要进行技术复杂的修复手术,俗称 "突击队手术"。关于这种手术的结果还没有很好的描述。本研究的目的是检查我们中心的突击队手术效果。我们确定了 2004-2021 年间所有同时接受主动脉瓣和二尖瓣置换术的患者。在363名患者中,有41人接受了主动脉瓣帘重建术。研究人员采用生存分析和多变量模型来检验结果和死亡风险因素。中位年龄为 52(IQR 44-71)岁。术前,41 位患者中有 4 位(9.8%)出现肾功能衰竭,41 位患者中有 10 位(24.4%)出现中风。41 位患者中有 25 位(61.0%)最常见的手术指征是心内膜炎。41名患者中有25名(61.0%)接受了再次胸骨切开术,41名患者中有23名(56.1%)曾接受过人工瓣膜手术。手术死亡率为41例中的14例(34.1%),41例患者中有8例(9.5%)接受了永久起搏器治疗。1年、3年和5年的存活率分别为55.4%(95%置信区间,40.6-75.5%)、50.3%(35.0-72.3%)和37.7%(19.3-73.9%)。Cox比例危险回归确定既往胸骨切开术(HR 4.76,95% CI 1.21-18.73)和女性性别(HR 1.39,95% CI 1.17-13.82)为死亡率的风险因素。接受主动脉瓣帘重建手术的患者属于高危人群,手术适应症复杂。由于围手术期的发病率和死亡率较高,只有在必要时才能进行该手术。尽管前期发病率较高,但对于在最初住院期间存活下来的患者来说,治疗效果仍然很好。
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Surgical Outcomes After Reconstruction of the Aortomitral Curtain

Repair of concomitant aortic and mitral valvular disease with involvement of the aortomitral curtain requires a technically complex operation colloquially termed the commando procedure. Surgical outcomes of this procedure are not well described. The objective of this study was to examine outcomes of the commando procedure at our center. We identified all patients undergoing concomitant aortic and mitral valve replacements from 2004–2021. Of 363 patients, 41 underwent reconstruction of the aortomitral curtain. Survival analysis and multivariable modeling were used to examine outcomes and risk factors for mortality. The median age was 52 (IQR 44-71) years. Preoperatively, 4 of 41 (9.8%) patients had renal failure, and 10 of 41 (24.4%) had a stroke. The most common surgical indication was endocarditis in 25 of 41 (61.0%) patients. 25 of 41 (61.0%) patients underwent redo sternotomy, and 23 of 41 (56.1%) had previous prosthetic valves. Operative mortality was 14 of 41 (34.1%), and 8 of 41 (9.5%) patients received a permanent pacemaker. Survival at 1, 3, and 5 years was 55.4% (95% confidence interval (CI), 40.6–75.5%), 50.3% (35.0–72.3%), and 37.7% (19.3–73.9%) respectively. Cox proportional hazards regression identified previous sternotomy (HR 4.76, 95% CI 1.21–18.73), and female gender (HR 1.39, 95% CI 1.17–13.82) as risk factors for mortality. Patients undergoing reconstruction of the aortomitral curtain represent a high-risk population with complex surgical indications. Due to high perioperative morbidity and mortality, this procedure should be performed only when necessary. Despite a high up front morbidity burden, outcomes remain favorable for patients who survive the initial hospitalization.

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来源期刊
Seminars in Thoracic and Cardiovascular Surgery
Seminars in Thoracic and Cardiovascular Surgery Medicine-Pulmonary and Respiratory Medicine
CiteScore
5.80
自引率
0.00%
发文量
324
审稿时长
12 days
期刊介绍: Seminars in Thoracic and Cardiovascular Surgery is devoted to providing a forum for cardiothoracic surgeons to disseminate and discuss important new information and to gain insight into unresolved areas of question in the specialty. Each issue presents readers with a selection of original peer-reviewed articles accompanied by editorial commentary from specialists in the field. In addition, readers are offered valuable invited articles: State of Views editorials and Current Readings highlighting the latest contributions on central or controversial issues. Another prized feature is expert roundtable discussions in which experts debate critical questions for cardiothoracic treatment and care. Seminars is an invitation-only publication that receives original submissions transferred ONLY from its sister publication, The Journal of Thoracic and Cardiovascular Surgery. As we continue to expand the reach of the Journal, we will explore the possibility of accepting unsolicited manuscripts in the future.
期刊最新文献
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