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The State of the Art in Acquired Tracheoesophageal Fistula Management. 获得性气管食管瘘治疗的最新进展。
IF 2.5 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2026-01-09 DOI: 10.1053/j.semtcvs.2025.11.004
Konstantina Spetsotaki, Sandra Guzzella, Rolf Schuepbach, Andre Mueller, Carolin Steinack, Christian Alexander Gutschow, Isabelle Opitz

Tracheoesophageal fistula (TEF) is a challenging, complex condition with a wide spectrum of underlying causes and clinical manifestations. TEF management requires a deep understanding of anatomical characteristics, underlying conditions, and a multidisciplinary approach to optimize the diagnostic pathways and treatment allocations. The management of benign and malignant TEF has shown progress in its effective treatment; however, surgical techniques remain a challenge and are often complemented by innovative stent deployment strategies. Concurrently, new techniques are being added to the treatment landscape, however, the evidence remains largely limited to case reports. Nevertheless, despite the substantial advancements in the management of TEF, there remains a lack of consensus or established guidelines for this condition in the adult population and treatment approach remains highly individualized. The aim of this article is to summarize the current treatment strategies for this complex disease.

气管食管瘘(TEF)是一种具有挑战性的复杂疾病,具有广泛的潜在病因和临床表现。TEF的管理需要深入了解解剖特征、潜在条件,并采用多学科方法优化诊断途径和治疗分配。良性和恶性TEF的治疗在有效治疗方面取得了进展;然而,手术技术仍然是一个挑战,并且经常辅以创新的支架部署策略。与此同时,新技术正在被加入到治疗领域,然而,证据仍然主要局限于病例报告。然而,尽管在TEF的管理方面取得了实质性进展,但在成人人群中仍然缺乏共识或既定的指导方针,治疗方法仍然高度个性化。本文的目的是总结目前的治疗策略,为这种复杂的疾病。
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引用次数: 0
Why Magnetic Resonance Imaging Is Invaluable for the Evaluation of Thymic Masses. 为什么磁共振成像对胸腺肿块的评估是无价的。
IF 2.5 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2026-01-07 DOI: 10.1053/j.semtcvs.2025.11.002
Maria Clara N Lorca, Michael Lanuti, Jeanne B Ackman

The widespread and ever-expanding use of computed tomography for disease, trauma, cardiac imaging, and lung cancer screening has led to increased incidental detection of indeterminate thymic nodules and masses on CT. Chest MRI provides increased diagnostic specificity and delineation of disease extent and should therefore both reduce unnecessary thymectomy and improve clinical management of thymic masses.

计算机断层扫描在疾病、创伤、心脏成像和肺癌筛查中的广泛和不断扩大的应用,导致CT上不确定胸腺结节和肿块的偶然发现增加。胸部MRI提供了更高的诊断特异性和疾病范围的描述,因此应该减少不必要的胸腺切除术和改善胸腺肿块的临床管理。
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引用次数: 0
Shall We Step Outside the Cage? Non-Intercostal Approaches to Pulmonary Lobectomy. 我们可以走出笼子吗?肺叶切除术的非肋间入路。
IF 2.5 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-12-31 DOI: 10.1053/j.semtcvs.2025.11.001
Luciano Bulgarelli Maqueda, Maxime Têtu, Omar Abdulaziz M Alkathiri, Ohud Fahad Alreshidi, Pedro Guimarães Rocha Lima, Joseph Seitlinger, Stéphane Renaud, Pasquale Ferraro, Moishe Liberman

Pulmonary lobectomy via a minimally invasive surgery (MIS) approach represents the current standard of care in early-stage non-small cell lung cancer. However, MIS has mostly relied on intercostal incisions, with the inherent risk of intercostal nerve injury. As a result, several non-intercostal approaches were developed. However, published data on the subject remain scarce. We aim to review existing non-intercostal MIS lobectomy techniques to specifically assess their feasibility and safety. Systematic review from 2010-2025. The outcomes for feasibility and safety were conversion rate and 30-day mortality, respectively. A total of 17 studies were included in the qualitative synthesis. From a combined total of 2376 patients included in the study, 66% (n = 1570) underwent a non-intercostal lobectomy. Among these, 83.5% (n = 1312) were performed via a subxiphoid approach, 15% (n = 236) via subcostal incisions. Among the studies that reported on outcomes, conversion rate and mortality were reported, respectively, as 4.3% (n = 53/1228) and 0.4% (n = 1/259) for subxiphoid approach, 1.4% (n = 2/140) and 0.7% (n = 1/140) for subcostal incisions. There has been growing interest in various non-intercostal approaches to pulmonary lobectomy over the past decade. Notably, recent studies suggest a shift toward higher-quality research and a transition from subxiphoid video-assisted to subcostal robotic-assisted thoracic surgery techniques. Among these, Outside the Cage (OTC) RATS robotic-assisted thoracic surgery emerges as the only fully non-intercostal reproducible robotic approach. Despite encouraging early data, further efforts are required to rigorously evaluate potential benefits. Nonetheless, the evidence to date suggests that it could be both feasible and safe to step "outside the cage."

背景:经微创手术(MIS)入路的肺叶切除术是目前治疗早期非小细胞肺癌的标准。然而,MIS大多依赖于肋间切口,存在肋间神经损伤的固有风险。因此,发展了几种非肋间入路。然而,关于这一主题的公开数据仍然很少。我们的目的是回顾现有的非肋间MIS肺叶切除术技术,具体评估其可行性和安全性。方法:2010 - 2025年进行系统评价。可行性和安全性指标分别为转换率和30天死亡率。结果:定性综合共纳入17项研究。研究共纳入2376例患者,其中66% (n=1570)接受了非肋间肺叶切除术。其中,83.5% (n=1312)通过剑突下入路(SX), 15% (n=236)通过肋下切口(SC)。在报道预后的研究中,SX的转换率和死亡率分别为4.3% (n=53/1228)和0.4% (n=1/259), sc的转换率和死亡率分别为1.4% (n=2/140)和0.7% (n=1/140)。结论:在过去十年中,人们对各种非肋间入路肺叶切除术的兴趣越来越大。值得注意的是,最近的研究表明,向更高质量的研究和从剑突下视频辅助到肋下机器人辅助(RATS)技术的转变。其中,笼外(OTC) RATS成为唯一完全非肋间可重复的机器人方法。尽管早期数据令人鼓舞,但需要进一步努力严格评估潜在效益。尽管如此,迄今为止的证据表明,走出“牢笼”可能既可行又安全。
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引用次数: 0
Thymic Surgery for Neoplasm: Perspectives on the Optimal Approach. 胸腺肿瘤手术:最佳入路的展望。
IF 2.5 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-12-26 DOI: 10.1053/j.semtcvs.2025.11.003
Matthew Skovgard, Bernard Park

Thymic epithelial tumors require tailored surgical strategies to optimize outcomes. This review synthesizes current evidence on surgical approaches, emphasizing the critical roles of tumor stage, anatomy, and multidisciplinary planning. For early-stage thymic epithelial tumors (Stage I/II), minimally invasive techniques (video-assisted thoracic surgery, robotic-assisted) demonstrate equivalent oncologic outcomes to open surgery, with reduced morbidity, shorter hospitalization, and faster recovery. Recent propensity-matched studies highlight robotic thymectomy's advantages, including lower blood loss and complication rates, though operative times may be longer. Locally advanced tumors (Stage IIIA-B) demand meticulous R0 resection, often necessitating open approaches for complex resections involving pericardium, phrenic nerves, or great vessels. Induction therapy shows promise in converting borderline resectable tumors and improving R0 rates. For Stage IVA disease, surgery within multimodal regimens may enhance survival, though benefits depend on pleural burden and histology, underscoring the need for individualized management. Emerging debates focus on refining resection extent. Lymphadenectomy gains traction for thymic carcinomas and advanced thymomas due to nodal metastasis risks, while partial thymectomy for early-stage tumors remains controversial, requiring randomized trials to balance oncologic efficacy against long-term immunologic consequences. Thymic surgery continues to evolve, prioritizing R0 resection while integrating minimally invasive advancements and multimodal therapies. Centralized, high-volume centers and international collaboration remain pivotal to addressing these rare malignancies. Future research must clarify lymphadenectomy's role, validate partial thymectomy, and optimize induction strategies through prospective trials.

胸腺上皮肿瘤(TETs)需要量身定制的手术策略来优化结果。这篇综述综合了目前关于手术入路的证据,强调肿瘤分期、解剖和多学科规划的关键作用。对于早期TETs (I/II期),微创技术(VATS,机器人辅助)显示出与开放手术相同的肿瘤结果,发病率降低,住院时间缩短,恢复速度更快。最近的倾向匹配研究强调了机器人胸腺切除术的优势,包括更低的出血量和并发症发生率,尽管手术时间可能更长。局部晚期肿瘤(IIIA-B期)需要细致的R0切除,通常需要开放入路进行涉及心包、膈神经或大血管的复杂切除。诱导治疗在转移边缘可切除肿瘤和提高R0率方面显示出希望。对于IVA期疾病,多模式手术方案可提高生存率,但益处取决于胸膜负荷和组织学,强调个性化管理的必要性。新兴的争论集中在细化切除程度上。由于淋巴结转移的风险,淋巴结切除术对胸腺癌和晚期胸腺瘤的治疗效果较好,而部分胸腺切除术对早期肿瘤的治疗仍然存在争议,需要随机试验来平衡肿瘤疗效和长期免疫后果。胸腺手术继续发展,优先考虑R0切除,同时整合微创进展和多模式治疗。集中的、大容量的中心和国际合作仍然是解决这些罕见恶性肿瘤的关键。未来的研究必须明确淋巴结切除术的作用,验证部分胸腺切除术,并通过前瞻性试验优化诱导策略。
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引用次数: 0
Novel Robotic Technology for Lung Cancer Surgery. 肺癌手术的新型机器人技术。
IF 2.5 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-11-18 DOI: 10.1053/j.semtcvs.2025.10.006
Dena G Shehata, Ammara A Watkins, Elliot L Servais
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引用次数: 0
Commentary: History Will Judge. 评论:历史将作出判断。
IF 2.5 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-11-14 DOI: 10.1053/j.semtcvs.2025.10.005
Jacob A Klapper
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引用次数: 0
Commentary: Synchronized Success: The Role of Teamwork in Modern Thoracic Surgery. 评论:同步成功:团队合作在现代胸外科中的作用。
IF 2.5 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-11-04 DOI: 10.1053/j.semtcvs.2025.10.003
Paula Ugalde Figueroa, Narjust Florez
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引用次数: 0
Commentary: Telescopic Sleeve - Don't Lose Focus on the Fundamentals. 评论:套筒-不要失去对基本面的关注。
IF 2.5 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-11-01 DOI: 10.1053/j.semtcvs.2025.10.004
Ryan A J Campagna, Paul L Feingold
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引用次数: 0
Management of Endograft Infection after Thoracic Endovascular Aortic Repair. 胸主动脉血管内修复术后移植物感染的处理。
IF 2.5 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-10-30 DOI: 10.1053/j.semtcvs.2025.10.002
Yuki Ikeno, Adrian Ramirez, Muhammad A Khan, Michael J Troncone, Harleen Sandhu, Charles C Miller, Hazim J Safi, Anthony L Estrera, Akiko Tanaka

Endograft infections following thoracic endovascular treatment are rare but associated with high morbidity and mortality. This study describes our experience with the surgical management of infections involving descending thoracic and thoracoabdominal aorta. The study retrospectively reviewed patients who underwent open descending thoracic and thoracoabdominal aortic aneurysm repair between January 1991 and March 2025, including cases of stent graft infections and secondary aortobronchial or aortoenteric fistula. Perioperative characteristics, operative outcomes and overall survival were evaluated. Of 2220 patients who underwent descending thoracic and thoracoabdominal aortic aneurysm repair, 20 patients (0.9%) received surgical treatment for endograft infections: 8 with endograft infection; 7 with aortoesophageal fistula; and 5 with aortobronchial fistula. The extent of repair involved the descending thoracic aneurysm in 18 patients (90%), and thoracoabdominal aortic aneurysm in 2 patients (10%). Endograft explantation and in-situ aortic reconstruction were performed in 19 patients (95%) while flap reconstruction was utilized in 16 patients (80%). Operative mortality was 6 patients (30%). Postoperative stroke occurred in 1 patient (5%) and temporary paraparesis also occurred in 1 patient (5%). Overall survival was 43.5% at 1 year and 36.3% at 5 years. Management of endograft infection involving the descending thoracic and thoracoabdominal aortic aneurysm remains challenging. Surgical repair, including endograft explantation, in-situ reconstruction, and flap installation, yielded acceptable mortality and morbidity rates in this high-risk patient population.

目的:胸腔血管内治疗后的内移植物感染是罕见的,但与高发病率和死亡率相关。本研究描述了我们手术治疗胸降主动脉和胸腹主动脉感染的经验。方法:回顾性分析1991年1月至2025年3月期间行开放性降支胸腹主动脉瘤修复术的患者,包括支架感染和继发性主动脉支气管或主动脉肠瘘的病例。评估围手术期特征、手术结果及总生存期。结果:2220例行降胸胸腹主动脉瘤修复术的患者中,有20例(0.9%)因内移植物感染接受手术治疗:8例为内移植物感染;主动脉食管瘘7例;主动脉支气管瘘5例。修复范围包括18例(90%)的胸降动脉瘤和2例(10%)的胸腹主动脉瘤。19例(95%)采用内移植物外植和主动脉原位重建,16例(80%)采用皮瓣重建。手术死亡率6例(30%)。术后卒中1例(5%),暂时性截瘫1例(5%)。1年和5年的总生存率分别为43.5%和36.3%。结论:处理累及降胸和胸腹主动脉瘤的内移植物感染仍然具有挑战性。手术修复,包括内移植物外植、原位重建和皮瓣安装,在这一高危患者群体中产生了可接受的死亡率和发病率。
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引用次数: 0
Daily Chest X-Rays for Cardiovascular Surgery Patients: Mandatory or Myth? 心血管手术患者每日胸部x光片:强制还是神话?
IF 2.5 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-10-30 DOI: 10.1053/j.semtcvs.2025.09.001
Jonathan Gale, Gurmeet Singh

Routine daily chest radiographs (CXR) in intensive care units (ICUs), including cardiovascular (CVICUs) and cardiothoracic (CTICUs), are widely used for early complication detection during the post-operative period. However, evidence suggests that this practice lacks clinical utility, with low diagnostic and therapeutic yields. The evidence consistently demonstrates that an on-demand CXR strategy, performed only for specific clinical indications, offers comparable patient safety, reduced radiation exposure, and substantial cost savings without increasing adverse outcomes, ICU length of stay, or mortality. For post-cardiothoracic surgery patients, complications such as pleural effusions and pneumothoraces are of important concern, yet routine CXRs rarely identify such abnormalities, with very few requiring intervention. Data support an on-demand approach, even after procedures such as chest tube removal, as clinical signs and symptoms are reliable indicators of complications. Transitioning from routine to on-demand CXR practices aligns with evidence-based guidelines, including Choosing Wisely® and the Critical Care Societies Collaborative recommendations. This approach promotes high-value care, minimizes unnecessary imaging, and supports the safe, cost-effective management of ICU patients. Routine CXRs should be reconsidered as standard practice in favor of tailored, patient-specific imaging strategies.

在重症监护病房(icu),包括心血管(CVICUs)和心胸(CTICUs),常规每日胸片(CXR)被广泛用于术后早期并发症的检测。然而,有证据表明,这种做法缺乏临床效用,诊断和治疗收益低。证据一致表明,仅针对特定临床指征的按需CXR策略可提供相当的患者安全性,减少辐射暴露,并节省大量成本,而不会增加不良后果、ICU住院时间或死亡率。对于心胸外科术后患者,胸腔积液和气胸等并发症是一个重要的问题,但常规的x光检查很少发现这些异常,很少需要干预。数据支持按需方法,即使在诸如胸管拔除等手术之后,因为临床体征和症状是并发症的可靠指标。从常规到按需CXR实践的过渡符合循证指南,包括明智选择®和重症监护协会协作建议。这种方法促进了高价值的护理,最大限度地减少了不必要的成像,并支持对ICU患者的安全、经济有效的管理。常规的cxr应该重新考虑作为标准的做法,有利于量身定制的,针对患者的成像策略。
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引用次数: 0
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Seminars in Thoracic and Cardiovascular Surgery
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