{"title":"草药介导的纳米硒颗粒的制备、表征及其抗菌活性的评价。","authors":"Deepika Katyal, Ravindra Kumar Jain, Swapna Sreenivasagan","doi":"10.4103/japtr.japtr_182_22","DOIUrl":null,"url":null,"abstract":"<p><p>This study aimed to synthesize selenium nanoparticles (SeNPs) using stevia plant leaves and to evaluate the antimicrobial effect of nano-sized particles of selenium. A new organic synthesis of nano-sized selenium particles was done in this study. In this study, stevia leaves for the synthesis of nano-sized particles along with sodium selenite were done. This mixture was mixed homogeneously using an orbital shaker overnight. The color change indicated the formation of SeNPs. The SeNPs were evaluated for their size and shape and their antimicrobial property was assessed. SeNPs showed excellent antimicrobial activity against <i>Candida albicans</i> at 100 μL concentration. At 25 μL and 50 μL, <i>C. albicans</i> showed intermediate susceptibility to SeNPs which also indicated a good antimicrobial potential. Following <i>C. albicans</i>, SeNPs showed good antimicrobial potential against <i>Streptococcus mutans</i> at all concentrations. SeNPs possessed good antimicrobial activity against most common oral pathogens.</p>","PeriodicalId":14877,"journal":{"name":"Journal of Advanced Pharmaceutical Technology & Research","volume":null,"pages":null},"PeriodicalIF":1.4000,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3c/4c/JAPTR-13-525.PMC9926589.pdf","citationCount":"0","resultStr":"{\"title\":\"Herbal-mediated preparation of nano-sized particles of selenium, its characterization, and evaluation of its antimicrobial activity.\",\"authors\":\"Deepika Katyal, Ravindra Kumar Jain, Swapna Sreenivasagan\",\"doi\":\"10.4103/japtr.japtr_182_22\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>This study aimed to synthesize selenium nanoparticles (SeNPs) using stevia plant leaves and to evaluate the antimicrobial effect of nano-sized particles of selenium. A new organic synthesis of nano-sized selenium particles was done in this study. In this study, stevia leaves for the synthesis of nano-sized particles along with sodium selenite were done. This mixture was mixed homogeneously using an orbital shaker overnight. The color change indicated the formation of SeNPs. The SeNPs were evaluated for their size and shape and their antimicrobial property was assessed. SeNPs showed excellent antimicrobial activity against <i>Candida albicans</i> at 100 μL concentration. At 25 μL and 50 μL, <i>C. albicans</i> showed intermediate susceptibility to SeNPs which also indicated a good antimicrobial potential. Following <i>C. albicans</i>, SeNPs showed good antimicrobial potential against <i>Streptococcus mutans</i> at all concentrations. SeNPs possessed good antimicrobial activity against most common oral pathogens.</p>\",\"PeriodicalId\":14877,\"journal\":{\"name\":\"Journal of Advanced Pharmaceutical Technology & Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2022-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3c/4c/JAPTR-13-525.PMC9926589.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Advanced Pharmaceutical Technology & Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/japtr.japtr_182_22\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Pharmacology, Toxicology and Pharmaceutics\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Advanced Pharmaceutical Technology & Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/japtr.japtr_182_22","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Pharmacology, Toxicology and Pharmaceutics","Score":null,"Total":0}
Herbal-mediated preparation of nano-sized particles of selenium, its characterization, and evaluation of its antimicrobial activity.
This study aimed to synthesize selenium nanoparticles (SeNPs) using stevia plant leaves and to evaluate the antimicrobial effect of nano-sized particles of selenium. A new organic synthesis of nano-sized selenium particles was done in this study. In this study, stevia leaves for the synthesis of nano-sized particles along with sodium selenite were done. This mixture was mixed homogeneously using an orbital shaker overnight. The color change indicated the formation of SeNPs. The SeNPs were evaluated for their size and shape and their antimicrobial property was assessed. SeNPs showed excellent antimicrobial activity against Candida albicans at 100 μL concentration. At 25 μL and 50 μL, C. albicans showed intermediate susceptibility to SeNPs which also indicated a good antimicrobial potential. Following C. albicans, SeNPs showed good antimicrobial potential against Streptococcus mutans at all concentrations. SeNPs possessed good antimicrobial activity against most common oral pathogens.
期刊介绍:
Journal of Advanced Pharmaceutical Technology & Research (JAPTR) is an Official Publication of Society of Pharmaceutical Education & Research™. It is an international journal published Quarterly. Journal of Advanced Pharmaceutical Technology & Research (JAPTR) is available in online and print version. It is a peer reviewed journal aiming to communicate high quality original research work, reviews, short communications, case report, Ethics Forum, Education Forum and Letter to editor that contribute significantly to further the scientific knowledge related to the field of Pharmacy i.e. Pharmaceutics, Pharmacology, Pharmacognosy, Pharmaceutical Chemistry. Articles with timely interest and newer research concepts will be given more preference.