胰腺癌患者的身体组成。

IF 0.6 Q4 SURGERY Polish Journal of Surgery Pub Date : 2022-05-23 DOI:10.5604/01.3001.0015.8570
Magdalena Kowalska, Zbigniew Kamocki
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引用次数: 0

摘要

尽管在诊断和治疗方面取得了重大进展,但胰腺癌的预后仍然很差。手术治疗仍然是唯一的治愈选择。遗憾的是,能够根治性切除肿瘤的患者比例不到 20%。切除手术难度大,并发症发生率高。导致围手术期发病率高的重要因素之一是营养不良,约 85% 的胰腺癌患者会出现营养不良,而且营养不良的进展速度很快。现有报告显示,胰腺癌患者的身体成分无疑会发生变化,而且取决于癌症的分期、部位和类型。此外,是否进行抗肿瘤治疗也起着重要作用。在胰腺癌患者中,体重减轻似乎很早就会出现,身体脂肪和骨骼肌质量等参数也会下降,并随着肿瘤的生长和疾病的进展而恶化。上述数据表明,了解患者的身体成分并观察其变化可能是生存期和并发症发生的预后因素。此外,有报道称,根据身体成分而非传统措施确定化疗剂量有助于减少治疗的毒性。因此,了解患者的身体成分似乎是一个重要方面。
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Body composition of patients suffering from pancreatic cancer.

Pancreatic cancer, despite significant progress in diagnosis and treatment still has poor prognosis. Surgical treatment remains the only cure option. Unfortunately, the percentage of patients in whom radical tumor removal is possible is less than 20%. Resection procedures are burdened with a high degree of difficulty, as well as a high complication rate. One of the important factors contributing to the high morbidity of the perioperative period is malnutrition, and rapidly progressing malnutrition which occurs in about 85% of pancreatic cancer patients. Abnormal nutritional status is closely related to a change in the composition in the body.The aim of the study was to determine the changes in the body composition of patients with pancreatic cancer and their consequences based on the results of the current research.The available reports have shown that the body composition of a patient with pancreatic cancer undoubtedly changes and is dependent on the stage, location and type of cancer. Furthermore, the fact if antitumor treatment is applied or not, also plays a significant role.It appears that in patients with pancreatic cancer, weight loss with a decline in parameters such as body fat and skeletal muscle mass appears early and worsens as the tumor grows and the disease progresses. The above data suggest that knowing the patient's body composition and observing its changes may be a prognostic factor for survival and the occurrence of complications. Additionally, there are reports that dosing chemotherapy based on body composition rather than conventional measures can help reduce the toxicity of the treatment. Therefore, knowing the patient's body composition seems to be an important aspect.

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CiteScore
1.10
自引率
0.00%
发文量
62
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