Noé Atamari-Anahui, Héctor Nuñez-Paucar, Luz K Paredes-Rodríguez, Meylin Escalante-Oviedo, Johana L Córdova-Meza, Kerly M Cruz-Vallejos, Carlos Valera-Moreno, Alex Untiveros-Tello
{"title":"儿童感染后闭塞性细支气管炎:秘鲁一家儿科医院的病例系列。","authors":"Noé Atamari-Anahui, Héctor Nuñez-Paucar, Luz K Paredes-Rodríguez, Meylin Escalante-Oviedo, Johana L Córdova-Meza, Kerly M Cruz-Vallejos, Carlos Valera-Moreno, Alex Untiveros-Tello","doi":"10.24875/BMHIM.23000045","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Postinfectious bronchiolitis obliterans is a rare lung disease; there are limited reports in South America.</p><p><strong>Case report: </strong>We report 10 patients with this disease diagnosed at the Instituto Nacional de Salud del Niño-Breña (Lima-Peru). The median age at diagnosis was 19 months and all patients had a history of severe acute respiratory infection. The most frequent symptoms were cough, respiratory distress, wheezing, and hypoxemia. The mosaic attenuation pattern was the most frequent on the tomography. All the patients had positive serology for adenovirus. The treatment received was methylprednisolone pulses, azithromycin, hydroxychloroquine, and inhaled corticosteroids. No patient died during the follow-up.</p><p><strong>Conclusions: </strong>In previously healthy children with a history of severe acute respiratory infection and persistent bronchial obstructive symptoms, the diagnosis of postinfectious bronchiolitis obliterans should be considered. This is the first report in Peru with a therapeutic regimen adapted to our institution.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"80 5","pages":"312-319"},"PeriodicalIF":0.6000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Postinfectious bronchiolitis obliterans in children: case series at a pediatric hospital in Peru.\",\"authors\":\"Noé Atamari-Anahui, Héctor Nuñez-Paucar, Luz K Paredes-Rodríguez, Meylin Escalante-Oviedo, Johana L Córdova-Meza, Kerly M Cruz-Vallejos, Carlos Valera-Moreno, Alex Untiveros-Tello\",\"doi\":\"10.24875/BMHIM.23000045\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Postinfectious bronchiolitis obliterans is a rare lung disease; there are limited reports in South America.</p><p><strong>Case report: </strong>We report 10 patients with this disease diagnosed at the Instituto Nacional de Salud del Niño-Breña (Lima-Peru). The median age at diagnosis was 19 months and all patients had a history of severe acute respiratory infection. The most frequent symptoms were cough, respiratory distress, wheezing, and hypoxemia. The mosaic attenuation pattern was the most frequent on the tomography. All the patients had positive serology for adenovirus. The treatment received was methylprednisolone pulses, azithromycin, hydroxychloroquine, and inhaled corticosteroids. No patient died during the follow-up.</p><p><strong>Conclusions: </strong>In previously healthy children with a history of severe acute respiratory infection and persistent bronchial obstructive symptoms, the diagnosis of postinfectious bronchiolitis obliterans should be considered. This is the first report in Peru with a therapeutic regimen adapted to our institution.</p>\",\"PeriodicalId\":9103,\"journal\":{\"name\":\"Boletín médico del Hospital Infantil de México\",\"volume\":\"80 5\",\"pages\":\"312-319\"},\"PeriodicalIF\":0.6000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Boletín médico del Hospital Infantil de México\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.24875/BMHIM.23000045\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"PEDIATRICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Boletín médico del Hospital Infantil de México","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.24875/BMHIM.23000045","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PEDIATRICS","Score":null,"Total":0}
Postinfectious bronchiolitis obliterans in children: case series at a pediatric hospital in Peru.
Background: Postinfectious bronchiolitis obliterans is a rare lung disease; there are limited reports in South America.
Case report: We report 10 patients with this disease diagnosed at the Instituto Nacional de Salud del Niño-Breña (Lima-Peru). The median age at diagnosis was 19 months and all patients had a history of severe acute respiratory infection. The most frequent symptoms were cough, respiratory distress, wheezing, and hypoxemia. The mosaic attenuation pattern was the most frequent on the tomography. All the patients had positive serology for adenovirus. The treatment received was methylprednisolone pulses, azithromycin, hydroxychloroquine, and inhaled corticosteroids. No patient died during the follow-up.
Conclusions: In previously healthy children with a history of severe acute respiratory infection and persistent bronchial obstructive symptoms, the diagnosis of postinfectious bronchiolitis obliterans should be considered. This is the first report in Peru with a therapeutic regimen adapted to our institution.
期刊介绍:
The Boletín Médico del Hospital Infantil de México is a bimonthly publication edited by the Hospital Infantil de México Federico Gómez. It receives unpublished manuscripts, in English or Spanish, relating to paediatrics in the following areas: biomedicine, clinical, public health, clinical epidemology, health education and clinical ethics. Articles can be original research articles, in-depth or systematic reviews, clinical cases, clinical-pathological cases, articles about public health, letters to the editor or editorials (by invitation).