儿童感染后闭塞性细支气管炎:秘鲁一家儿科医院的病例系列。

Noé Atamari-Anahui, Héctor Nuñez-Paucar, Luz K Paredes-Rodríguez, Meylin Escalante-Oviedo, Johana L Córdova-Meza, Kerly M Cruz-Vallejos, Carlos Valera-Moreno, Alex Untiveros-Tello
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引用次数: 0

摘要

背景:传染性后闭塞性细支气管炎是一种罕见的肺部疾病;在南美洲有有限的报告。病例报告:我们报告了10例在国立卫生研究院Niño-Breña(利马-秘鲁)诊断出此病的患者。诊断时的中位年龄为19个月,所有患者均有严重急性呼吸道感染史。最常见的症状是咳嗽、呼吸窘迫、喘息和低氧血症。在断层扫描上以马赛克衰减模式最为常见。所有患者血清腺病毒检测结果均为阳性。所接受的治疗是甲泼尼龙脉冲、阿奇霉素、羟氯喹和吸入皮质类固醇。随访期间无患者死亡。结论:对于既往健康且有严重急性呼吸道感染史和持续支气管阻塞性症状的儿童,应考虑感染后闭塞性细支气管炎的诊断。这是秘鲁第一个采用适合我们机构的治疗方案的报告。
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Postinfectious bronchiolitis obliterans in children: case series at a pediatric hospital in Peru.

Background: Postinfectious bronchiolitis obliterans is a rare lung disease; there are limited reports in South America.

Case report: We report 10 patients with this disease diagnosed at the Instituto Nacional de Salud del Niño-Breña (Lima-Peru). The median age at diagnosis was 19 months and all patients had a history of severe acute respiratory infection. The most frequent symptoms were cough, respiratory distress, wheezing, and hypoxemia. The mosaic attenuation pattern was the most frequent on the tomography. All the patients had positive serology for adenovirus. The treatment received was methylprednisolone pulses, azithromycin, hydroxychloroquine, and inhaled corticosteroids. No patient died during the follow-up.

Conclusions: In previously healthy children with a history of severe acute respiratory infection and persistent bronchial obstructive symptoms, the diagnosis of postinfectious bronchiolitis obliterans should be considered. This is the first report in Peru with a therapeutic regimen adapted to our institution.

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来源期刊
CiteScore
1.60
自引率
0.00%
发文量
73
审稿时长
20 weeks
期刊介绍: The Boletín Médico del Hospital Infantil de México is a bimonthly publication edited by the Hospital Infantil de México Federico Gómez. It receives unpublished manuscripts, in English or Spanish, relating to paediatrics in the following areas: biomedicine, clinical, public health, clinical epidemology, health education and clinical ethics. Articles can be original research articles, in-depth or systematic reviews, clinical cases, clinical-pathological cases, articles about public health, letters to the editor or editorials (by invitation).
期刊最新文献
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