用牛尿绿色合成纳米银:抗菌和血液生物相容性研究

Q3 Materials Science JCIS open Pub Date : 2021-10-01 DOI:10.1016/j.jciso.2021.100023
A.S. Santhosh , S. Sandeep , H.M. Manukumar , B. Mahesh , N. Kumara Swamy
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引用次数: 9

摘要

本研究以牛尿为还原剂和封盖剂,制备了新型绿色合成牛尿银纳米颗粒(表弟颗粒)。用紫外可见光谱、x射线衍射、傅里叶变换红外光谱、扫描电子显微镜和透射电子显微镜对牛尿银纳米颗粒进行了标记。采用动态光散射法探测表弟粒子的大小,确定其为47.8 nm。此外,通过细胞壁破坏和膜穿孔,表妹颗粒证明了对大肠杆菌和耐甲氧西林金黄色葡萄球菌的生物杀灭作用。扫描电镜(SEM)确定了大肠杆菌的绝对杀生物膜不稳定性,而循环伏安法(CV)证实了耐甲氧西林金黄色葡萄球菌的膜穿孔机制。此外,堂兄颗粒的血液亲和性强化了它可能是治疗动物传染病的有希望的候选者。调查推断,表妹颗粒采用了一种简单、廉价、环保的方式,使用牛尿作为还原剂。
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Green synthesis of silver nanoparticles using cow urine: Antimicrobial and blood biocompatibility studies

In this research, new green synthesized cow urine silver nanoparticles (CoUSiN particles) were accomplished by using cow urine as a reducing and capping agent. The cow urine silver nanoparticles have been marked by UV–Visible spectroscopy, X-ray diffraction, Fourier Transformer Infrared spectroscopy, Scanning Electron Microscopy, and Transmission Electron Microscopy. The size of the CoUSiN particles had probed by using a dynamic light scattering method and was determined to be 47.8 ​nm. Further, CoUSiN particles evidenced biocidal venture against Escherichia coli and methicillin-resistant Staphylococcus aureus through cell wall destruction and membrane poring. The SEM established the absolute biocidal sheath destabilization of Escherichia coli and whereas the cyclic voltammetry (CV) bolstered the membrane poring mechanism on methicillin-resistant Staphylococcus aureus. Further, the blood congenial nature of CoUSiN particles fortified that it can be a promising candidate to heal epizootic diseases. The inquiry infers that the CoUSiN particles incorporated adopting a simple, inexpensive, eco-friendly modus using cow urine as a reducing agent.

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来源期刊
JCIS open
JCIS open Physical and Theoretical Chemistry, Colloid and Surface Chemistry, Surfaces, Coatings and Films
CiteScore
4.10
自引率
0.00%
发文量
0
审稿时长
36 days
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