[苄基亚硝基脲(BzNH)对bd大鼠的致癌活性[作者译]。

S Ivankovic
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引用次数: 1

摘要

慢性每周口服和皮下注射n -苄基-n -亚硝基脲分别诱导bd大鼠前胃癌和局部s.c肉瘤。这证实了该化合物的局部致癌作用。在bd大鼠的产前实验中,未发现BzNH的致癌作用。
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[Carcinogenic activity of benzyl-nitrosourea (BzNH) in BD-rats (author's transl)].

Chronic weekly oral and subcutaneous administration of N-Benzyl-N-nitrosourea induced carcinomas of the forestomach and local s.c. sarcomas respectively in BD-rats. This confirms a local carcinogenic effect of the compound. In prenatal experiments in BD-rats no carcinogenic effect of BzNH could be found.

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