2019 - 2021年全国儿童医院新生儿败血症病原菌检测

Nguyen Thi Ngoc Tu,, Truong Thi Mai Hong, Le Ngoc Duy, Hoang Thi Bich Ngoc, Le Thi Ha
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引用次数: 0

摘要

败血症是一种危及生命的疾病,是对感染因子的反应,导致组织和器官受损。脓毒症会对新生儿造成严重后果,因为它的死亡率、后遗症和致残率很高。目前,新生儿脓毒症的治疗仍面临诸多困难,如诊断较晚、病原体模型抗生素选择不当等。这种疾病的死亡率仍然很高。国家儿童医院新生儿败血症病原菌检测(2019 - 2021)对2019年12月至2021年4月期间越南国立儿童医院新生儿中心收治的85例足月婴儿血培养阳性样本进行描述性研究。革兰氏阴性菌占51%,革兰氏阳性菌占38.8%,念珠菌占9.4%。金黄色葡萄球菌是常见病因(28.2%),大肠杆菌和肺炎克雷伯菌占较高比例(16.5%)。敏感性较高的抗生素有万古霉素、氨曲南、莫西沙星、厄他培南、左氧氟沙星、美罗南。
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DETERMINING THE PATHOGENS OF NEONATAL SEPSIS AT THE NATIONAL CHILDREN'S HOSPITAL (2019 – 2021)
Sepsis is a life-threatening condition responding to an infectious agent causesdamage to tissues and organs. Sepsis causes serious consequences in neonates due tohighrates of mortality and sequelae and disability. Currently, the treatment ofneonatal sepsis is still facing many difficulties due to late diagnosis, inappropriateantibiotic selection for the pathogen model. The mortality rate of the disease is stillhigh. Determining the pathogens of neonatal sepsis at the National Children'sHospital (2019 – 2021). A descriptive study was conducted on 85 positive bloodculture samples of full-term infants admitted to the Neonatal Center of VietnamNational Children’s Hospital in the period from 12/2019 to 4/2021.Gram-negative bacteria accounted for the highest percentage 51%, Grampositive bacteria accounted for 38.8%, Candida accounted for 9.4%. S. aureus is thecommon cause of disease (28.2%), E. coli and K. pneumonia account for a highproportion (16.5%). Antibiotics with high sensitivity are vancomycin, aztreonam,moxiflocaxin, ertapenem, levofloxacin, meronem.
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