禽霍乱主动免疫的研究

K. Sakamoto
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引用次数: 1

摘要

1. 干燥的家禽霍乱减毒,或通过摇晃,干燥或加热被证明是没有价值的疫苗。用杀菌剂、禽霍乱侵袭剂和浓缩肉汤培养的病原菌单价和多价杀灭效果较好;然而,在接种部位产生脓肿是这些疫苗的一个共同缺陷。单价和多价核蛋白均产生了非常令人满意的结果,使接受治疗的动物具有坚实的免疫力,没有任何不良反应。最后,我要感谢N. NITTA教授在这项工作中提出的宝贵建议。
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A STUDY IN ACTIVE IMMUNIZATION AGAINST FOWL CHOLERA
1. The drying of fowl cholera attenuated, or killed by shaking, drying or heating proved to be of no value as vaccines.2. The organism killed with disinfectants, fowl cholera aggressine and condensed broth culture of the organism, both mono- and polyvalent, gave better results; the production of an abscess at the site of inoculation was, however, a common defect of these vaccines.3. Nucleoproteids, both mono- and polyvalent, gave very satisfactory results, conferring a solid immunity to animals treated with no ill effects.Finally I wish to express my best thanks to Prof. N. NITTA for his valuable suggestions in this work.
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