近红外传感器输出电压随溶液中葡萄糖浓度的函数模型

E. S. Julian, K. Prawiroredjo, G. Tjahjadi
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引用次数: 7

摘要

全世界糖尿病患者的数量每年都在增加,包括印度尼西亚。糖尿病是中风、心脏病、肾衰竭、下肢截肢的主要原因,也是导致死亡的主要原因之一。为了控制血糖水平,糖尿病患者必须根据一定的医疗指导、饮食、运动和规律用药,尽可能多地检测血糖水平。不幸的是,目前的血糖检测不方便、不舒服,甚至会给糖尿病患者或患者带来疼痛;因此,一个无创的血糖测量是非常需要的。虽然在这方面已经做了一些研究工作,但一种成功的非侵入性方法仍在寻找中。为了在这一研究领域有所贡献,我们研究了不同浓度溶液中葡萄糖浓度对近红外传感器输出电压的影响,作为获得成功的无创血糖仪的初步研究。本文报道了近红外传感器输出电压随葡萄糖浓度变化的模型。近红外传感器的主要部件是1450nm发光二极管(LED)作为光源,对该波长敏感的光电二极管作为传感器件。LED与光电二极管之间的距离为15mm。溶液中葡萄糖浓度分别为50mg /dl、100mg /dl、200mg /dl、300mg /dl和400mg /dl。在直径为40mm的丙烯酸圆柱体中,每个浓度分别填充5ml葡萄糖溶液。结果表明,葡萄糖浓度越高,传感器输出电压越低。线性趋势线与这些数据吻合得很好。相关系数为−0.99,表明传感器输出电压与葡萄糖浓度之间存在较强的相关性。
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The Model of near infrared sensor output voltage as a function of glucose concentration in solution
The number of people with diabetes increases every year in the whole world, including Indonesia. Diabetes is a major cause of stroke, heart attack, kidney failure, lower limb amputation and one of the leading causes of death. In order to manage their blood glucose level, diabetics have to test their blood glucose level as often as possible according to certain medical guidance, diet, exercise and consume medicine regularly. Unfortunately, the current blood glucose testing is inconvenient and uncomfortable, even cause pain for diabetic or patient; therefore, a noninvasive blood glucose measurement is highly desirable. Although several research works have already been done in this area, a successful noninvasive method is still in search. In order to contribute in this research area, we study the effect of glucose concentration in solutions with different concentration to the output voltage of a near infrared sensor as a preliminary research to obtain a successful noninvasive blood glucose meter. In this paper, we reported the model of near infrared sensor output voltage as a function of glucose concentration. The main components of the near infrared sensor are a 1450 nm light emitting diode (LED) as light source, and a photodiode that is sensitive to that wavelength as the sensing device. The distance between LED and photodiode is 15mm. The solutions have 50 mg/dl, 100 mg/dl, 200 mg/dl, 300 mg/dl, and 400 mg/dl glucose concentrations. An acrylic cylinder with 40 mm diameter was filled with 5 ml glucose solution for each concentration. The results show that higher glucose concentrations produce lower sensor output voltages. The linear trend line shows good fit with those data. The value of correlation coefficient is −0.99, which indicates strong relationship between the sensor output voltages and glucose concentrations.
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