生物传感双墩平台的构建

M. Patterson, K. Hansen, D. Walker, M. Qumsiyeh, H. Yue, G. Subramanyam
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引用次数: 0

摘要

本文描述了用于生物传感应用的双墩平台的成功构建。两个桥墩是直线的,它们之间有一个可调的间隙,间隙距离在60-200纳米之间变化。桥墩的近端与允许测试的共面波导结构相连。通过使用JEOL激光系统烧蚀定制的MMA/PMMA堆叠,创建了基本的桥墩结构。然后使用标准电子束沉积技术在硅上沉积一层Ti-Au。结构的电磁测试与SEM图像相关联,以表征电性能和间隙完整性。整体设计是通过将分子拴在桥墩的远端从而完成电路来创建一个生物传感桥。生物桥的类型和组成提供了传感器的选择性和灵敏度。
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Construction of a twin-pier platform for biological sensing
This paper describes the successful construction of a twin-pier platform for use in biological sensing applications. The two piers are inline and have a tunable gap between them, with gap distance varying between 60-200 nm. The proximal ends of the piers are contiguous with a Co-Planar Waveguide structure that allows for testing. The basic pier structure was created by ablation of a customized MMA/PMMA stack using a JEOL laser system. A layer of Ti-Au was then deposited on silicon using standard electron beam deposition techniques. Electromagnetic testing of the structures was correlated with SEM imagery for characterization of electrical properties and gap integrity. The overall design is to create a biological sensing bridge by tethering molecules across the distal ends of the piers thereby completing the circuit. The type and composition of biological bridge provides sensor selectivity and sensitivity.
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