苹果醋对表皮葡萄球菌和痤疮丙酸杆菌生长的抑菌效果

I. Prabowo, Arifa Shaliha, Oktania Sandra Puspita
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摘要

痤疮是由痤疮丙酸杆菌、表皮葡萄球菌和金黄色葡萄球菌引起的炎症引起的一种皮肤病。苹果醋含有抗菌化合物,如醋酸、绿原酸、多酚、生物碱、类黄酮和糖苷。本研究旨在研究苹果醋中抗菌成分对表皮葡萄球菌和痤疮假单胞菌生长的体外抑制作用。本研究采用Mueller Hinton琼脂培养基的圆盘扩散法。25%、50%、75%和100%浓度的苹果醋对痤疮假丝酵母生长形成抑制带,50%、75%和100%浓度的苹果醋对表皮假丝酵母生长形成抑制带。当浓度为75%时,对痤疮假单胞菌和表皮假单胞菌的抑制面积分别为8825 mm和3725 mm。检验结果痤疮棘球蚴与表皮棘球蚴的单因素方差分析(p) < 0.005。结果表明,苹果醋对痤疮假丝酵母和表皮假丝酵母均有抑制作用,其中对痤疮假丝酵母的抑制作用强于对表皮假丝酵母的抑制作用。
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ANTIMICROBIAL EFFECTIVENESS OF APPLE CIDER VINEGAR IN THE GROWTH OF Staphylococcus epidermidis and Propionibacterium acnes
Acne is a skin disease caused by Propionibacterium acnes, Staphylococcus epidermidis-, and Staphylococcus aureus-induced inflammation. Apple cider vinegar contains antibacterial compounds such as acetic acid, chlorogenic acid, polyphenols, alkaloids, flavonoids, and glycosides. This study is conducted to determine the effectiveness of antibacterial compounds contained in apple cider vinegar against the growth of S.epidermidis and P.acnes, in vitro. The study used the disc diffusion method by utilizing the Mueller Hinton Agar medium. The apple cider vinegar inhibition zone was formed at the concentration of 25%, 50%, 75%, and 100% against the growth of P.acnes, whereas the inhibition zone against S.epidermidis was formed at the concentration of 50%, 75%, and 100%. The highest inhibition zone against P. acnes was 8,825 mm and against S.epidermidis was 3,725 mm at the concentration of 75%. Test results One-way ANOVA on P.acnes and Kruskal Wallis to S.epidermidis obtained (p) <0,005. This study concludes the effectiveness of apple cider vinegar in inhibiting the growth of P. acnes and S. epidermidis, where the effectiveness against P. acnes was stronger than against S. epidermidis.
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